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13篇 您的检索式:作者名="Losinno"
    题名 作者 年代 出处 被引量
1Trypanosoma rangeli:growth in mammalian cells in vitro and action of a repositioned drug(17-AAG)and a natural extract(Artemisia sp.essential oil)显示文摘Trypanosoma rangeli and T.cruzi are both parasitic unicellular species that infect humans.Unlike T.cruzi,the causative agent of Chagas disease,T.rangeli is an infective and non-pathogenic parasite for humans,but pathogenic for vectors from the Rhodnius genus.Because both species can coexist in different hosts and overlap their infective cycles but very little is known about the infection of T.rangeli in mammalian cells,we decided to characterize both the development of this parasite in cell culture and the effect of therapeutic agents with potential trypanocidal action on it.We found that T.rangeli exhibits a cycle of infection in Vero cells similar to that for T.cruzi and that the repurposed drug,17-AAG,and the natural extract Artemisia sp.essential oil produce a toxic effect on epimastigotes showing a trypanocidal action from the fifth day of culture.Both treatments also affected the infection of trypomastigotes and reduced the capacity of replication of amastigotes of T.rangeli.Since T.cruzi/T.rangeli coinfection cases have been reported,the finding of drugs with potential activity against both species could be significant in the future.Furthermore,studies of susceptibility of both species to drugs could also help to know the different mechanisms of pathogenicity in humans displayed by T.cruzi that are absent in T.rangeli.Ana Laura CIMADOR Emeli Luciana GALANTE Lucila Ibel MUNOZ Patricia Silvia ROMANO Antonella Denisse LOSINNO Maria Cristina VANRELL 2019BIOCELL2019,43,1:1
2Usefulness of contrast-enhanced perfusional sonography in the assessment of hepatocellular carcinoma hypervascular at spiral computed tomography显示文摘Stefano Gaiani Natascia Celli Fabio Piscaglia Laura Cecilioni Franco Losinno Francesco Giangregorio Mikaela Mancini Patrizia Pini Fabio Fornari Luigi Bolondi 2004Journal of Hepatology2004,,3:1
3Renovascular disease in diabetes mellitus:Treatment by percutaneous transluminal renal angioplasty显示文摘Zuccala A Losinno F Zucchelli A 1998Nephrol Dial Transplant1998,13,:1
4Natural killer cell activity against cultural melanoma cells : a dye-reduction technique with subtypes 显示文摘LOSINNO C WINES B D JOHN T G 1992Nat Immun1992,11,4:1
5Usefulness of contrast-enhanced perfusional sonography in the assessment of hepatocellular carcinoma hypervascular at spiral computed tomography显示文摘Stefano Gaiani Natascia Celli Fabio Piscaglia Laura Cecilioni Franco Losinno Francesco Giangregorio Mikaela Mancini Patrizia Pini Fabio Fornari Luigi Bolondi 2004Journal of Hepatology2004,,3:1
6Renal scintigraphy versus renal vein activity for identifyiilg and treating renovascular hypertension显示文摘Cbiarini C Esposti ED Losinno F 1982Nephron1982,32,:1
7Assessment ofcontamination by intensive cattle activity through electricalresistivity tomography显示文摘Sainato C M Losinno B N Malleville H J 2012Journal of Applied Geophysics2012,76,:1
8Renovascular disease in diabetes mellitus: treatment by percutaneous transluminal renal angioplasty显示文摘Zuccala A Losinno F Zucchelli A 1998Nephrol Dial Transplant1998,13,8:1
9Embolism predictors of infective endocarditis显示文摘Cremona AR Borga S J Losinno JF 2007Medicina2007,67,1:1
10Transjugular intrahepatic splenosystemic shunt in patient with portal vein thrombosis 显示文摘Trevisani F Rossi C Losinno F 2001J Hepatal2001,35,:1
11Assessment of contamination by intensive cattle activity through electricalresistivity tomography 显示文摘SAINATO C M LOSINNO B N MALLEVILLE H J 2012Journal of Applied Geophysics2012,76,:1
12Renovascular disease in diabetes mellitus:treatment by percutaneous transluminal renal angioplasty显示文摘Zuccala A Losinno F Zucchelli A 1998Nephrol Dial Transplant1998,13,:1
13Endometrial tissue concentrations of enrofloxacin after intrauterine administration to mares 显示文摘FUMUSO E CHECURA C LOSINNO L 2002Veterinary Research Communication2002,26,:1
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