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| 1 | Efficacy and safety of botulinum toxin in treatment of anismus: A systematic review显示文摘AIM: To evaluate the efficacy and safety of botulinum toxin type A(BTX-A) in the management of patients with anismus. METHODS: An organized search of published literature was conducted using electronic databases including: Pub Med/MEDLINE, and Cochrane Central Register of Control ed Trials, also an internet-based search using 'Google Scholar' service was conducted. Both comparative and observational studies were included. We excluded irrelevant articles, editorials, case reports, reviews, and meta-analyses. The studies that followed the patients less than 6 mo were excluded. Variables collected were demographic data of the patients, technique of BTX-A injection and number of sessions, short-term and longterm clinical improvement, post-injection changes in electromyography(EMG), defecography, manometry, and balloon expulsion test, and complications recorded after BTX-A injection.RESULTS: Seven studies comprising 189 patients were included in the review. The median age of the patients was 41.2 years and female-to-male ratio was 1.3:1. The median dose of BTX-A injected per procedure was 100 IU(range, 20-100 IU). Lateral injection was done in five trails and combined lateral and posterior injections in two trials. Three studies used endorectal ultrasonographyguided technique, one study used EMG-guided technique,whereas the remaining three studies used manual palpation with the index finger. The median percentage of patients who reported initial improvement of symptoms was 77.4%(range 37.5%-86.7%), this percentage declined to a median of 46%(range 25%-100%) at 4 mo after injection of BTX-A. Rates of improvement evaluated by balloon expulsion test, EMG, and defecography ranged between(37.5%-80%),(54%-86.7%), and(25%-86.6%), respectively. Fourteen(7.4%) patients developed complications after injection of BTX-A. Complication rates across the studies ranged from 0% to 22.6%. CONCLUSION: Initial satisfactory improvement of symptoms after BTX-A injection remarkably deteriorated after 3 mo of the procedure. However, repeated injection may provide better sustained results with no additional morbidities. Further analysis of more patients is necessary to conclude the safety of BTX-A for the treatment of anismus. | Sameh Hany Emile Hossam Ayman Elfeki Hosam Ghazy Elbanna Mohamed Youssef Waleed Thabet Tito M Abd El-Hamed Basem Said Ahmed Lotfy | 2016 | World Journal of Gastrointestinal Pharmacology and Therapeutics2016，7，3： | 3 |
| 2 | Inter-ethnic marriages and severity of coronary artery disease:A multicenter study of Arabian Gulf States显示文摘AIM To assess the association of inter-ethnic vs intra-ethnic marriage with severity of coronary artery disease(CAD) in men undergoing angiography.METHODS We conducted a prospective multicenter,multi-ethnic,cross sectional observational study at five hospitals in Saudi Arabia and the United Arab Emirates,in which we used logistic regression analysis with and without adjustment for baseline differences. RESULTS Data were collected for 1068 enrolled patients undergoing coronary angiography for clinical indications during the period of April 1^(st),2013 to March 30^(th),2014. Ethnicities of spouses were available only for male patients. Of those enrolled,687 were married men and constituted the cohort for the present analysis. Intra-ethnic marriages were reported in 70% and inter-ethnic marriages in 30%. After adjusting for baseline differences,interethnic marriage was associated with lower odds of having significant CAD [adjusted odds ratio 0.52(95%CI:0.33,0.81)] or multi-vessel disease(MVD) [adjusted odds ratio 0.57(95%CI:0.37,0.86)]. The adjusted association with left main disease showed a similar trend,but was not statistically significant [adjusted odds ratio 0.74(95%CI:0.41,1.32)]. The association between interethnic marriage and the presence of significant CAD and MVD was not modified by number of concurrent wives(P interaction > 0.05 for both).CONCLUSION Among married men undergoing coronary angiography,inter-ethnic,as compared to intra-ethnic,marriage is associated with lower odds of significant CAD and MVD. | Amin Daoulah Salem Al-kaabi Amir Lotfi Mushabab Al-Murayeh S Ali Nasseri Waleed Ahmed Salah N Al-Otaibi Mohamed N Alama Osama E Elkhateeb Amy J Plotkin Majed M Malak Khalid Alshali Mohamed Hamzi Saleh Al Khunein Mohammed Abufayyah Alawi A Alsheikh-Ali | 2017 | World Journal of Cardiology2017，9，4： | 2 |
| 3 | The World Health Organization's WHOQOL-BREF quality of life assessment:psychometric properties and results of the international field trial-A report from the WHOQOL group显示文摘 | Skevington SM Lotfy M O'Connell KA | 2004 | Qual Life Res2004，13，2： | 1 |
| 4 | Production of haploid and doubled haploid plants of melon ( Cucumis melo L) for use in breeding for multiple virus resistance 显示文摘 | Lotfi M Alan AR Henning MJ | 2003 | Plant Cell Rep2003，21，： | 1 |
| 5 | Inelastic initial local buckling of skew thin thickness-tapered plates with and without intermediate supports using the isoparametric spline finite strip method 显示文摘 | Lotfi S Azhari M Heidarpour A | 2011 | Thin-Walled Structures2011，49，： | 1 |
| 6 | Evaluation of fibroblast at- tachment in root conditioning with Er, Cr:YSGG laser versus ED- TA:A SEM study 显示文摘 | Fekrazad R Lotfi G Harandi M | 2015 | Microsc Res Tech2015，78，4： | 1 |
| 7 | Evolutionary origins,diversification,and biogeography of liver flukes(Digenea,Fasciolidae)显示文摘 | LOTFY W M BRANT S V DEJONG R J | 2008 | Am J Trop Med Hyg2008，79，2： | 1 |
| 8 | Mesen- chymal stein cells: new aspect in cell -based regenerative therapy 显示文摘 | Mohammadian M Shamsasenjan K Lotfi Nezhad P | 2013 | Adv Pharm Bull2013，3，2： | 1 |
| 9 | An algorithmic method to extend TOPSIS for decision-making problems with interval data显示文摘 | G R JAHANSHAHLOO F H LOTFI M IZADIKHAH | | 0，，02： | 1 |
| 10 | Extension of the TOPSIS method for decision making problems with fuzzy data显示文摘 | Jahanshahloo G R Lotfi F H Izadikhah M | 2006 | Journal of Applied Mathematics2006，181，2： | 1 |
| 11 | An algorithmic method to extend TOPSIS for decision-mak- ing problems with interval data显示文摘 | JAHANSHAHLOO G R LOTFI F H IZADIKHAH M | 2006 | Applied Mathematics and Computation2006，175，2： | 1 |
| 12 | The effect of glucagon-like peptide-1 in the management of diabetes mellitus:cellular and molecular mechanisms显示文摘 | Lotfy M Singh J Rashed H | 2014 | Cell Tissue Res2014，358，2： | 1 |
| 13 | Stability indicating electrochemical methods for the determination of meclophenoxate hydrechloride and pyritinol dihydrochloride using ion-selective membrane electrodes显示文摘 | EI-BARDICY M G LOTFY H M EI-TARRAS M F | 2007 | Yakugaku Zasshi2007，127，1： | 1 |
| 14 | Nonpharmacologic strate- gies for managing common chemotherapy adverse effects:a system- atic review显示文摘 | Lotfi - Jam K Carey M Jefford M | 2008 | J Clin Oncol2008，26，34： | 1 |
| 15 | An algorithmic method to extend TOPSIS for decision-making problems with interval data显示文摘 | JAHANSHAHLOO G R LOTFI F H IZADIKHAH M | 2006 | Applied Mathematics and Computation2006，175，2： | 1 |
| 16 | Elevated serum level of interleukin(IL)-18,interferon(IFN)-gamma and 9 soluble Fas in patients with pulmonary complications in tuberculosis显示文摘 | El-Masry S Lotfy M Nasif WA | 2007 | Acta Microbiol Immunol Hung2007，54，： | 1 |
| 17 | Extension of theTOPSIS method for decision-making problems with fuzzy data显示文摘 | Jahanshahloo G R Hosseinzadeh Lotfi F Izadikhah M | 2006 | App liedMathematics and Computation2006，181，： | 1 |
| 18 | Significance of matrix metalloproteinase 9 and CD34 expressions in esophage- al carcinoma: correlation with DNA content 显示文摘 | El-kenawy AeI-M Lotfy M El-kotta A | 2005 | J Clin Gastroenterol2005，39，9： | 1 |
| 19 | A particle swarm- based genetic algorithm for scheduling in an agile environment 显示文摘 | LOTFI K G SHERIFA M ASHRAF O N | 2008 | Computers & Industrial Engineering2008，55，3： | 1 |
| 20 | Analysis of Power Consumption and Linearity in Capacitor Digital-to-analog Converters Used in Successive Approximation ADCs 显示文摘 | Saberi M Lotfi R Mafinezhad K | 2011 | IEEE Transactions on Circuits and Systems:Regular Papers2011，58，8： | 1 |
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