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		题名	作者	年代	出处	被引量
	1	Effects of food processing on the nutrient composition of Pyropia yezoensis products revealed by NMR-based metabolomic analysis 显示文摘	YeYF YangR LouYJ ChenJJ YanXJ TangHR	2014	Journal of Food and Nutrition Research2014，2，10：	1
	2	Mechanism of activation of mouse liver microsomal glutations S—transferase by paracetamol treatment显示文摘Microsomal glutathion S-transferase(mGST) is one of the important detoxifcation enzymes in vivo,its modifying activation by drugs has been paid more attention to in pertinent field recently.This study was to explore the influence of paracetamol(Par) on mGST and its possible mechanism in vivo,and to further reveal the biological significance.Par is metabolized to N-acetyl-p-benzoquinone imine(NAPQI) by CYP2E1 and mGST is activated by sulfhydryl modification.	ZhenY LouYJ	2002	中国药理学与毒理学杂志2002，16，6：	0
	3	Mechanism on activation of mouse liver microsomal glutathione S—transferase—I by cyclophosphamide treatment in vivo显示文摘Membrane-associated microsomal glutathione S-transferase-I (mGST-I) is activated easily by alkyl agent or electrophilic metabolite.It was expected that toxic drugs and their metabolites derived from biotransformation by cytochrome P-450 maybe bind to and activate the mGST-I that can accelerate the metabolism of drugs to form inactive metabolites and simultaneously protect cell from damages.The aim of the present study was to investigate whether mGST-I is activated by cyclophosphamide(CP) treatment and to explore the possible mechanism in vivo.The results suggested that the main mechanism of mGST-I activation caused by overdose CP treatment is the unique sulfhydryl modification on its Cys-49.	ZhenY LouYJ	2002	中国药理学与毒理学杂志2002，16，6：	0

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