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| 1 | Practice of breast self-examination among high risk Chinese women in Hong Kong显示文摘The incidence of breast cancer in Hong Kong is increasing and breast self examination (BSE) as a screening tool is becoming more popular, especially among first degree relatives (FDR) of breast cancer victims BSE may be more applicable to Chinese women as their breast size is smaller This study explores the BSE practice in this group of women Methods A cross sectional study was conducted by sending questionnaires to 330 FDR of breast cancer patients treated in the Department of Surgery, University of Hong Kong BSE behavior was studied with respect to its frequency, awareness, completeness and confidence of practice Results 110 subjects returned the questionnaires with a response rate of 33% The mean age of the respondent was 37 years Only 57 women (52%) were practicers The practicers have a stronger BSE awareness ( P <0 01) and a lower mean score on thought barriers ( P =0 002) than the non practicers 40% of the practicers gain their BSE knowledge through clinicians and their mean period of practice was 3 2 years 68% of the practicers performed BSE completely The overall confidence rate was 35%, but the rate was 43% among those who performed complete BSE Thirteen factors possibly related to the completeness and rate of confidence of BSE examination were studied The only factor that significantly determined completeness was the time spent for each examination ( P =0 002) The complete practicers required a longer time than the incomplete practicers (6 60 and 2 96?min, respectively) Women with a stronger BSE intention ( P =0 001) and a lower mean score on thought barriers ( P =0 001) performed the examination confidently Conclusions Slightly over half of the FDR practice BSE The majority perform a complete BSE but they are not confident in finding abnormalities Women spending more time on BSE are associated with a higher rate of completeness However, only those with a stronger BSE intention and lesser thought barriers are more confident in their | Kelvin K C Ng, Fung S Y and Louis W C Chow DepartmentofSurgery (NgKKCandChowLWC)&NursingStudies (FungSY ) ,TheUniversityofHongKong ,QueenMaryHospital ,HongKong ,China | 2000 | Chinese Medical Journal2000，，12： | 4 |
| 2 | Assessment of the diagnostic performance and interobserver variability of endocytoscopy in Barrett's esophagus:A pilot ex-vivo study显示文摘AIM:To investigate a classification of endocytoscopy(ECS)images in Barrett’s esophagus(BE)and evaluate its diagnostic performance and interobserver variability.METHODS:ECS was applied to surveillance endoscopic mucosal resection(EMR)specimens of BE ex-vivo.The mucosal surface of specimen was stained with 1%methylene blue and surveyed with a catheter-type endocytoscope.We selected still images that were most representative of the endoscopically suspect lesion and matched with the final histopathological diagnosis to accomplish accurate correlation.The diagnostic performance and inter-observer variability of the new classification scheme were assessed in a blinded fashion by physicians with expertise in both BE and ECS and inexperienced physicians with no prior exposure to ECS.RESULTS:Three staff physicians and 22 gastroenterology fellows classified eight randomly assigned unknown still ECS pictures(two images per each classification)into one of four histopathologic categories as follows:(1)BEC1-squamous epithelium;(2)BEC2-BE without dysplasia;(3)BEC3-BE with dysplasia;and(4)BEC4-esophageal adenocarcinoma(EAC)in BE.Accuracy of diagnosis in staff physicians and clinical fellows were,respectively,100%and 99.4%for BEC1,95.8%and83.0%for BEC2,91.7%and 83.0%for BEC3,and95.8%and 98.3%for BEC4.Interobserver agreement of the faculty physicians and fellows in classifying each category were 0.932 and 0.897,respectively.CONCLUSION:This is the first study to investigate classification system of ECS in BE.This ex-vivo pilot study demonstrated acceptable diagnostic accuracy and excellent interobserver agreement. | Yutaka Tomizawa Prasad G Iyer Louis M Wongkeesong Navtej S Buttar Lori S Lutzke Tsung-Teh Wu Kenneth K Wang | 2013 | World Journal of Gastroenterology2013，19，46： | 2 |
| 3 | Reversible sleep - related stridor during vagus nerve stimulation显示文摘 | St Louis EK Faber K | 2010 | Epileptic Disord2010，12，1： | 1 |
| 4 | Intense muhiplication of prokaryotes associated with greening disease of citrus in phloem cells of dodder显示文摘 | GHOSH S K GIANNOTTI J LOUIS C | 1978 | Ann Phytopathol1978，9，4： | 1 |
| 5 | Virulence and molecular genotyping studies of Sporisorium reilianum isolates in sorghum显示文摘 | Louis K Prom Ramasamy Perumal Saradha R Erattaimuthu | 2011 | Plant Disease2011，95，5： | 1 |
| 6 | Restoring a sense of control during implementation 显示文摘 | Baronas A K Louis M R | 1988 | MIS Quarterly1988，12，1： | 1 |
| 7 | Long-term changes in marsh veg-etation in Sanjiang Plain, northeast China显示文摘 | LouY Zhao K Wang G | 2015 | Journal of Vegeta-tion Science2015，26，4： | 1 |
| 8 | Heightened responses to stressors in patients with inflame matory bowel disease显示文摘 | ASHKAN F ALl K LOUIS D | 2005 | Am J Gastroenterol2005，100，8： | 1 |
| 9 | The Stock Market Valuation of Research and Development Expenditures 显示文摘 | Chan Louis K C J Lakonishok T Sougiannis | | The Journal of Finance0，56，6： | 1 |
| 10 | Preclinical and clinical evaluations of ABX-EGF, a fully human anti-epidermal growth factor receptor antibody显示文摘 | Kenneth A Foon Xiao-Dong Yang Louis M Weiner Arie S Belldegrun Robert A Figlin Jeffrey Crawford Eric K Rowinsky Janice P Dutcher Nicholas J Vogelzang Jared Gollub John A Thompson Garry Schwartz Ronald M Bukowski Lorin K Roskos Gisela M Schwab | 2004 | International Journal of Radiation Oncology Biology Physics2004，，3： | 1 |
| 11 | Diabetes interferes with the bone formation by affecting the expression of transcription factors that regulate osteoblast differen-tiation 显示文摘 | Huafei LU Douglas K Louis C | 2003 | Endocrinology2003，144，1： | 1 |
| 12 | The promoter of the hu- man cystic fibrosis transmembrane conductance regulator gene directing SV40 T antigen expression induces malignant prolifera tion of ependymal cells in transgenic mice显示文摘 | Perraud F Yoshimura K Louis B | 1992 | Oncogene1992，7，5： | 1 |
| 13 | Reversion of the differentiated phenotype and maturation block in Sertoli cells in pathological human testis显示文摘 | Steger K Rey R Louis F | 1999 | Hum Reprod1999，14，1： | 1 |
| 14 | Expression of c-Myc protein in skin and synovium in psoriasis and psoriatic arthritis显示文摘 | Osterland C K Wilkinson R D St Louis E A | 1990 | Clin Exp Rheumatol1990，8，2： | 1 |
| 15 | Ground subsidence observation and a modified influence function method for complete subsidence prediction显示文摘 | SHEORY P R LOUI J P SIGNH K B | 2000 | International Journal of Rock Mechanics and Mining Sciences andGeomechanicsAbstracts2000，37，5： | 1 |
| 16 | Ground subsidence observations and a modified influence function method for complete subsidence prediction显示文摘 | Sheorey P R Loui J P Singh K B | 2000 | International Journal of Rock Mechanics and Mining Sciences2000，37，5： | 1 |
| 17 | Active strome- lysin-3(MMP-11) increases MCF-7 survival in three- dimensional Matrigel culture via activation of p42/p44 MAP-kinase显示文摘 | Fromigu6 O Louis K Wu E | 2003 | Int J Cancer2003，106，3： | 1 |
| 18 | Adoptive transfer of EBV-specific T cells results in sustained clinical responses in patients with locoregional nasopharyngeal carcinoma显示文摘 | Louis CU Straathof K Bollard CM | 2010 | J Immunother2010，33，9： | 1 |
| 19 | Enhancing the in vivo expansion of adoptively transferred EBV-specific CTL with lymphodepleting CD45 monoclonal antibodies in NPC patients显示文摘 | Louis CU Straathof K Bollard CM | | 0，，18： | 1 |
| 20 | Putting teachers at the center of reform: Learning schools and professional communities 显示文摘 | Louis K S Krnse S & Raywid M | 1996 | NASSP Bulletin1996，80，580： | 1 |
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