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| 1 | Non-transgenic Plant Genome Editing Using Purified Sequence-Specific Nucleases显示文摘Dear Editor, Sequence-specific nucleases,including zinc-finger nucleases,meganucleases,TAL effector nucleases (TALENs),and CRISPR/ Cas systems,have been used to introduce targeted mutations in a wide range of plant species (Voytas,2013;Baltes and Voytas,2015).However,delivery of these nucleases using traditional transformation methods (e.g.,particle bombardment,Agrobacterium or protoplast transformation) may result in undesired genetic alterations due to random insertion of nucleaseencoding DNA intothe host genome. | Song Luo Jin Li Thomas J. Stoddard Nicholas J. Baltes Zachary L. Demorest Benjamin M. Clasen Andrew Coffman Adam Retterath Luc Mathis Daniel F. Voytas Feng Zhang | 2015 | Molecular Plant2015，8，9： | 7 |
| 2 | Resection of Nonresectable Liver Metastases from Colorectal Cancer After Neoadjuvant Chemotherapy显示文摘 | Henry Bismuth René Adam Fran?is Lévi Christian Farabos Fabio Waechter Denis Castaing Pietro Majno Luc Engerran | 1996 | Annals of Surgery1996，，4： | 2 |
| 3 | Genetic engineering of glycinebetaine production toward enhaneing stress tolerance in plants : metabolic limitations显示文摘 | Jun Huang Rozina Hirji Luc Adam | 2000 | Plant Physio12000，122，： | 1 |
| 4 | The impact of lymph node status and features on oncological outcomes in urothelial carcinoma of the upper urinary tract (UTUC) treated by nephroureterectomy显示文摘 | Adil Ouzzane Pierre Colin Tarek P. Ghoneim Marc Zerbib Alexandre De La Taille Fran?ois Audenet Fabien Saint Nicolas Hoarau Emilie Adam Marie Dominique Azemar Henri Bensadoun Luc Cormier Olivier Cussenot Alain Houlgatte Gilles Karsenty Charlotte Maurin Fra | 2013 | World Journal of Urology2013，，1： | 1 |
| 5 | Repeat Hepatectomy for Colorectal Liver Metastases显示文摘 | Reńe Adam Henri Bismuth Denis Castaing Fabio Waechter Francisco Navarro Alvaro Abascal Pietro Majno Luc Engerran | 1997 | Annals of Surgery1997，，1： | 1 |
| 6 | 让人心生敬畏:Ken Block显示文摘Ken Block,漂移之王,邀请Matt Prior在银石赛道上享受一下漂移的乐趣,他所驾驶车辆的功率达到630kW。这款四驱野马车型被称作Hoonicorn。真棒??你确定是这样吗? | 吴玉凤 LUC LACEY ADAM WARNER | 2016 | 车主之友2016，0，3： | 0 |
| 7 | Effect of airplane transport of donor livers on post-liver transplantation survival显示文摘AIM To evaluate the effect of long haul airplane transport of donor livers on post-transplant outcomes. METHODS A retrospective cohort study of patients who received a liver transplantation was performed in Perth, Australia from 1992 to 2012. Donor and recipient characteristics information were extracted from Western Australian liver transplantation service database. Patients were followed up for a mean of six years. Patient and graft survival were evaluated and compared between patients who received a local donor liver and those who received an airplane transported donor liver. Predictors of survival were determined by univariate and multivariate analysis using cox regression.RESULTS One hundred and ninety-three patients received alocal donor liver and 93 patients received an airplane transported donor liver. Airplane transported livers had a significantly lower alanine transaminase(mean: 45 U/L vs 84 U/L, P = 0.035), higher donor risk index(mean: 1.88 vs 1.42, P < 0.001) and longer cold ischemic time(CIT)(mean: 10.1 h vs 6.4 h, P < 0.001). There was a weak correlation between CIT and transport distance(r2 = 0.29, P < 0.001). Mean follow up was six years and 93 patients had graft failure. Multivariate analysis found only airplane transport retained significance for graft loss(HR = 1.92, 95%CI: 1.16-3.17). One year graft survival was 0.88 for those with a local liver and was 0.71 for those with an airplane transported liver. One year graft loss was due to primary graft non-function or associated with preservation injury in 20.8% of recipients of an airplane transported liver compared with 4.6% in those with a local liver(P = 0.027). CONCLUSION Airplane transport of donor livers was independently associated with reduced graft survival following liver transplantation. | Yi Huang Gerry MacQuillan Leon A Adams George Garas Megan Collins Albert Nwaba Linjun Mou Max K Bulsara Luc Delriviere Gary P Jeffrey | 2016 | World Journal of Gastroenterology2016，22，41： | 0 |
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