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| 1 | Management of single pulmonary metastases from colorectal cancer:State of the art显示文摘Colorectal cancer(CRC)is one of the most common causes of death from cancer.Lung seeding occurs in approximately 10%of patients surgically treated for primary CRC with radical intent:the lung is the most common site of metastases after the liver.While surgical treatment of liver metastases is widely accepted to affect long-term outcomes,more controversial and not standardized is the therapy for CRC patients developing lung metastases.Experience suggests the potential curative role of pulmonary metastasectomy,especially in oligometastatic disease.However,the optimal strategy of care and the definition of prognostic factors after treatment still need to be defined.This review focused on the uncommon scenario of single pulmonary metastases from CRC.We explored pertinent literature and provide an overview of the epidemiology,clinical characteristics and imaging of single pulmonary metastases from CRC.Additionally,we identified the best available evidence for overall management.In particular,we analyzed the role and results of locoregional approaches(surgery,radiotherapy or ablative procedures)and their integration with systemic therapy. | Marco Chiappetta Lisa Salvatore Maria Teresa Congedo Maria Bensi Viola De Luca Leonardo PetraccaCiavarella Floriana Camarda Jessica Evangelista Vincenzo Valentini Giampaolo Tortora StefanoMargaritora Filippo Lococo | 2022 | World Journal of Gastrointestinal Oncology2022，14，4： | 2 |
| 2 | The ' small- world' topology of rock fracture networks显示文摘 | Luca Valentini Diego Perugini Giampiero Poli | 2007 | Physica A:Statistical Mechanics and its Apptications2007，377，： | 1 |
| 3 | Prognostic Value of Pathologic Complete Response After Neoadjuvant Therapy in Locally Advanced Rectal Cancer: Long-Term Analysis of 566 ypCR Patients显示文摘 | Carlo Capirci Vincenzo Valentini Luca Cionini Antonino De Paoli Claus Rodel Robert Glynne-Jones Claudio Coco Mario Romano Giovanna Mantello Silvia Palazzi Falchetti Osti Mattia Maria Luisa Friso Domenico Genovesi Cristiana Vidali Maria Antonietta Gambacor | 2008 | International Journal of Radiation Oncology Biology Physics2008，，1： | 1 |
| 4 | Evidence for a role of a dopamine/5 - HT6 receptor interaction in cocaine reinforcement 显示文摘 | Valentini V Piras G De Luca MA | 2013 | Neuropharmacology2013，65，： | 1 |
| 5 | Novel approaches to developing carbon nanotube based polymercomposites: Fundamental studies and nanoteeh applications 显示文摘 | Luca Valentini Kenny Jose M | 2005 | Polymer2005，46，： | 1 |
| 6 | Use of plasma fluorinated single-walled carbon nanotubes for the preparation of nanocomposites with epoxy matrix 显示文摘 | Luca Valentini Debora Puglia Fabio Carniato | 2008 | Composites Science and Technology2008，68，： | 1 |
| 7 | Measles-induced respiratory distress, air-leak and ARDS显示文摘 | M. Piastra R. Onesimo D. Luca L. Lancella L. Marzano G. Rosa D. Pietrini P. Valentini G. Conti | 2010 | European Journal of Clinical Microbiology & Infectious Diseases2010，，2： | 1 |
| 8 | Preparation and characterization of poly (butylene terephthalate)/graphene composites by in-situ polymerization of cyclic butylene terephthalate显示文摘 | Paola Fabbri Elena Bassoli Silvia Bittolo Bon Luca Valentini | 2012 | Polymer2012，，4： | 1 |
| 9 | Mechanical characterization and induced crystallization in nanocomposites of thermoplastics and carbon nanotubes显示文摘Nanocomposites built from polymers and carbon nanotubes(CNTs)are a promising class of materials.Computer modeling can provide nanoscale views of the polymer–CNT interface,which are much needed to foster the manufacturing and development of such materials.However,setting up periodic nanocomposite models is a challenging task.Here we propose a computational workflow based on Molecular Dynamics simulations. | Eduardo R.Cruz-Chú Gonzalo J.Villegas-Rodríguez Tobias Jäger Luca Valentini Nicola M.Pugno Konstantinos Gkagkas Frauke Gräter | 2020 | npj Computational Materials2020，，1： | 0 |
| 10 | Immunosuppressive treatment and radiotherapy in kidney transplant patients:A systematic review显示文摘BACKGROUND Immunosuppression(IS)therapy may contribute to cancer development.Some authors have proposed to reduce immunosuppression drugs dose in case of viral infections,in immunosuppression-related diseases,and in patients undergoing radiotherapy.The present analysis reports the results of a systematic review on kidney transplant recipients undergoing immunosuppression and radiotherapy.AIM To define if it is necessary reduce immunosuppression drugs during radiotherapy.METHODS The literature search was based on three electronic databases(Pubmed,Scopus,and Web of Science)using selected keywords linked through the'AND'and'OR'Boolean operators to build specific strings for each electronic search engine.Two researchers independently screened the citations,and disagreement was resolved by discussion or through the intervention of a third author.The review was conducted and reported according to the PRISMA statement.Extracted data were narratively synthesized,and,where possible,frequencies,percentages,and ranges were calculated.RESULTS The literature search resulted in 147 citations.After abstracts screening,21 records were selected for full-text evaluation.Fifteen of these were excluded,leaving six papers considered suitable for analysis.There is still no clear evidence that withdrawing antimetabolites and/or calcineurin inhibitors and/or mammalian target of rapamycin-inhibitors,as opposed to continuing maintenance IS,improves patient survival in kidney transplant recipients with cancer undergoing radiotherapy.Only few retrospective studies on small cancer patient cohorts are available in this setting,but without comparison of different immunosuppression treatments.Even where immunosuppression therapy was described,patient survival seemed to be correlated only with cancer stage and type.CONCLUSION The results of this systematic review do not support the reduction of immunosuppression dose in patients undergoing radiotherapy. | Valentina Lancellotta Andrea D'Aviero Bruno Fionda Calogero Casà Ilaria Esposito Francesco Preziosi Anna Acampora Fabio Marazzi György Kovács Barbara Alicja Jereczek-Fossa Alessio Giuseppe Morganti Vincenzo Valentini Maria Antonietta Gambacorta Jacopo Romagnoli Luca Tagliaferri | 2022 | World Journal of Radiology2022，14，3： | 0 |
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