|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Adhesive wear mechanisms uncovered by atomistic simulations显示文摘In this review, we discuss our recent advances in modeling adhesive wear mechanisms using coarse-grained atomistic simulations. In particular, we present how a model pair potential reveals the transition from ductile shearing of an asperity to the formation of a debris particle. This transition occurs at a critical junction size, which determines the particle size at its birth. Atomistic simulations also reveal that for nearby asperities, crack shielding mechanisms result in a wear volume proportional to an effective area larger than the real contact area. As the density of microcontacts increases with load, we propose this crack shielding mechanism as a key to understand the transition from mild to severe wear. We conclude with open questions and a road map to incorporate these findings in mesoscale continuum models. Because these mesoscale models allow an accurate statistical representation of rough surfaces, they provide a simple means to interpret classical phenomenological wear models and wear coefficients from physics-based principles. | Jean-Fran?ois MOLINARI Ramin AGHABABAEI Tobias BRINK Lucas FRéROT Enrico MILANESE | 2018 | Friction2018，6，3： | 6 |
| 2 | Interaction of the major inflammatory bowel disease susceptibility alleles in Crohn’s disease patients显示文摘AIM:To investigate the interaction of interleukin-23 receptor(IL23R)(rs1004819 and rs2201841),autophagy-related 16-like 1(ATG16L1)(rs2241880), caspase recruitment domain-containing protein 15 (CARD15)genes,and IBD5 locus in Crohn's disease(CD) patients. METHODS:A total of 315 unrelated subjects with CD and 314 healthy controls were genotyped.Interactions and specific genotype combinations of a total of eight variants were tested.The variants of IBD5locus(IGR2198a_1 rs11739135 and IGR2096a_1 rs12521868),CARD15(R702W rs2066845 and L1007fs rs2066847),ATG16L1(rs2241880)and IL23R (rs1004819,rs2201841)genes were genotyped by PCR-RFLP,the G908R(rs2066844)in CARD15 was determined by direct sequencing. RESULTS:The association of ATG16L1 T300A with CD was confirmed[P=0.004,odds ratio(OR)=1.69, 95%CI:1.19-2.41],and both IL23R variants were found to represent significant risk for the disease(P= 0.008,OR=2.05,95%CI:1.20-3.50 for rs1004819 AA;P<0.001,OR=2.97,95%CI:1.65-5.33 for rs2201841 CC).Logistic regression analysis of pairwise interaction of the inflammatory bowel disease (IBD)loci indicated that IL23R,ATG16L1,CARD15 and IBD5(IGR2198a_1)contribute independently to disease risk.We also analysed the specific combina- tions by pair of individual ATG16L1,IL23R rs1004819, rs2201841,IGR2198a_1,IGR2096a_1 and CARD15 genotypes for disease risk influence.In almost all cases,the combined risk of susceptibility pairs was higher in patients carrying two different risk-associated gene variants together than individuals with just one polymorphism.The highest OR was found for IL23R rs2201841 homozygous genotype with combination of positive CARD15 status(P<0.001,OR=9.15,95% CI:2.05-40.74). CONCLUSION:The present study suggests a cumulative effect of individual IBD susceptibility loci. | Veronika Csngei Luca Járomi EnikSáfrány Csilla Sipeky Lili Magyari Bernadett Faragó Judit Bene Noémi Polgár Lilla Lakner Patrícia Sarlós Márta Varga Béla Melegh | 2010 | World Journal of Gastroenterology2010，16，2： | 2 |
| 3 | Development of the Italian version of the National Institutes of Health Stroke Scale: It - NIHSS 显示文摘 | Pezzella FR Picconi O De Luca A | 2009 | Stroke2009，40，7： | 1 |
| 4 | The Development of the Italian version of the national institutes of health stroke scale : It-NIHSS 显示文摘 | Pezzella FR Picconi 0 De Luca A | 2009 | Stroke2009，40，7： | 1 |
| 5 | Silicon photonics phase and intensity modulators for flat frequency comb generation显示文摘Flat electro-optical frequency combs play an important role in a wide range of applications,such as metrology,spectroscopy,or microwave photonics.As a key technology for the integration of optical circuits,silicon photonics could benefit from on-chip,tunable,flat frequency comb generators.In this article,two different architectures based on silicon modulators are studied for this purpose.They rely on a time to frequency conversion principle to shape the comb envelope.Using a numerical model of the silicon traveling-wave phase modulators,their driving schemes are optimized before their performances are simulated and compared.A total of nine lines could be obtained within a 2 dB flatness,with a line-spacing ranging from 0.1 to 7 GHz.Since this tunability is a major asset of electro-optical frequency combs,the effect of segmenting the phase modulators is finally investigated,showing that the flat lines spacing could be extended up to 39 GHz by this method. | LUCAS DENIEL ERWAN WECKENMANN DIEGO PÉREZ GALACHO CHRISTIAN LAFFORGUE STÉPHANE MONFRAY CARLOS ALONSO-RAMOS LAURENT BRAMERIE FRÉDÉRIC BOEUF LAURENT VIVEN DELPHINE MARRIS-MORINI | 2021 | Photonics Research2021，9，10： | 1 |
| 6 | Development of the Italian version of the National Institutes of Health Stroke Scale:It-NIHSS显示文摘 | Pezzella FR Picconi O De Luca A | | 0，，7： | 1 |
| 7 | Development of the I- talian version of the National Institutes of Health Stroke Scale:It-NIHSS显示文摘 | Pezzella FR Picconi O De Luca A | 2009 | Stroke2009，40，7： | 1 |
| 8 | Axonal remodeling and synaptic differentiation in the cerebellum is regulated byWNT-7a signaling 显示文摘 | Hall AC Lucas FR Salinas PC | 2000 | Cell2000，100，5： | 1 |
| 9 | Development of the Italian version of the National Institutes of Health Stroke Scale : It - NIHSS 显示文摘 | Pezzella FR Picconi O De Luca A | 2009 | Stroke2009，40，7： | 1 |
| 10 | Axonal remodeling and synaptic differentiation in the cerebellum is regulated by WNT-7a signaling显示文摘 | Hall AC Lucas FR Salinas PC | 2000 | Cell2000，100，5： | 1 |
| 11 | Cross- institutional data exchange using the clinical document architecUlre (CDA) 显示文摘 | Marcel Lucas M'ullera Fr mk'Uckertb Thon~ts B '' urklec | 2004 | International Journal of Medical Informati cs2004，74，24： | 1 |
| 12 | Cross- institutional data exchange using the clinical document architecUlre (CDA) 显示文摘 | Marcel Lucas M'ullera Fr mk'Uckertb Thon~s B '' urklec | 2004 | International Journal of Medical Informati cs2004，74，24： | 1 |
| 13 | Development of the Italian version of the National Institutes of Health Stroke Scale: It- NIHSS显示文摘 | Pezzella FR Picconi 0 De Luca A | 2009 | Stroke2009，40，7： | 1 |
| 14 | Axonal remodeling and synaptic differentiation in the cerebellum is regulated by WNT-7a signaling显示文摘 | Hall AC Lucas FR Salinas PC | 2000 | Cell2000，100，5： | 1 |
| 15 | Association between the serotnin transporter promoter polymorphism and personality traits in a primarily female population sample显示文摘 | Greemberg BO Li Q Lucas FR | 2000 | Am J Med Genet2000，96，： | 1 |
| 16 | Axonal remodeling and synaptic differentiation in the cerebellum is regulated by WNT-7a signaling显示文摘 | Hall AC Lucas FR Salinas PC | 2000 | Cell2000，100，5： | 1 |
| 17 | Gastrointestinal sensitivity and gastroesophageal reflux disease显示文摘 | Annamaria Altomare Michele Pier Luca Guarino (Sara Emerenziani) Michele Cicala Asbj?rn Mohr Drewes Anne Lund Krarup Christina Brock Christian Lottrup Jens Br?ndum Fr?kj?r Rhonda F. Souza Gerardo Nardone Debora Compare | 2013 | Ann NY Acad Sci2013，，1： | 1 |
| 18 | Axonal remodeling and synaptic differentiation in the cerebellum is regulated by WNT-Ta signaling 显示文摘 | Hall AC Lucas FR Salinas PC | 2000 | Cell2000，100，5： | 1 |
| 19 | Inhibition of GSK3beta leading to the loss of phosphorylated MAP-1B is an early event in axonal remodelling induced by WNT-Ta or lithium 显示文摘 | Lucas FR Goold RG Gordon-Weeks PR | 1998 | J Cell Sci1998，111，10： | 1 |
| 20 | Development of the I- talian version of the National Institutes of Health Stroke Scale: It-NIHSS显示文摘 | Pezzella FR Picconi O De Luca A | 2009 | Stroke2009，40，7： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员