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| 1 | Interplay between nitric oxide and VIP in CCK-8-induced phasic contractile activity in the rabbit sphincter of Oddi显示文摘AIM: The sphincter of Oddi (SO) plays an important role in delivery of bile into the duodenum. To establish whether vasoactive intestinal polypeptide (VIP) and nitric oxide (NO) were involved in phasic contractile activity of the rabbit SO stimulated by cholecystokinin-octapeptide (CCK-8).METHODS: Isolated SO muscle rings were cleaned of fat and mounted horizontally on two small L-shaped hooksone of which was connected to a force transducer for the measurement of isometric tension. The experiments were carried out in a thermostatically controlled (37±0.2℃)organ bath (5 mL) containing Krebs solution. The organ fluid was gassed with 95% O2 and 50 mL/L CO2 to keep the pH at 7.40±0.05. Contractile responses to CCK-8 (1μmol/L) were evaluated in the presence and absence of N^G-nitro-L-arginine (LNNA), an inhibitor of NO synthase (100μmol/L), and (p-chloro-D-Phe^6-Leu^17)-VIP (VIPa,30μmol/L), a VIP receptor antagonist.RESULTS: CCK-8 stimulated the phasic activity of the SO.NO synthase inhibition increased the frequency and amplitude of contractions with a slight increase in developed tension.Pre-incubation with VIPa also attenuated this CCK-8 effect.The combined application of LNNA and VIPa abolished the phasic activity of the muscle rings with a marked increase in tension in response to CCK-8.CONCLUSION: VIP and NO together contribute to an increase in phasic activity of SO. | Attila Pálv(o|¨)lgyi Réka Sári József Németh Annamária Szabolcs István Nagy Péter Hegyi János Lonovics Zoltán Szilvássy | 2005 | World Journal of Gastroenterology2005，11，21： | 11 |
| 2 | 亚洲、欧洲及美洲人群中自身免疫性肝炎发病率和患病率的流行病学特点:系统综述与荟萃分析显示文摘【据《J Gastroenterol Hepatol 》2019 年10 月报道】题:亚洲、欧洲及美洲人群中自身免疫性肝炎发病率和患病率的流行病学特点:系统综述与荟萃分析(作者Lv T 等)自身免疫性肝炎(AIH)是一种自身免疫性肝病(多表现为慢性肝炎),好发于青少年及中老年女性,临床上以血清转氨酶和免疫球蛋白G 升高、自身抗体阳性和肝组织界面肝炎为主要特征。近年若干研究显示,AIH 的发病率和患病率有所增高,但是目前基于人群的AIH 流行病学研究结果存在很大差异性。 | 吕婷婷 李敏 孔媛媛 贾继东 LV T LI M ZENG N | 2020 | 临床肝胆病杂志2020，36，2： | 4 |
| 3 | Clinical study of changes of cerebral microcirculation in cerebral vasospasm after SAH显示文摘 | Chai W N Sun X C Lv F J | 2011 | Acta Neurochir Suppl2011，0，1： | 1 |
| 4 | The effect of chain extension method on the properties of polyurethane/SiO2 composites显示文摘 | LV Z P LI X N YU X | 2012 | Materials and Design2012，35，： | 1 |
| 5 | Experimental study and evaluation of latent heat storage in phase change materials wallboards 显示文摘 | Lv S L Feng G H Zhu N | 2007 | Energy and Buildings2007，39，10： | 1 |
| 6 | Compact High-power Red-green-blue Laser Light Source Generation From a Single Lithium Tantalite with Cascaded Domain Modulation显示文摘 | Xu P Zhao L N Lv X J | 2009 | Optics Express2009，17，： | 1 |
| 7 | The use of stable isotope techniques to assess zinc metabolism显示文摘 | Krebs N Miller LV Naake VL | 1995 | J Nutr Biochem1995，6，： | 1 |
| 8 | Long-term effect of convulsive behavior on the density of adenosine A1 and A 2A receptors in the rat cerebral cortex显示文摘 | Rebola N Porciuncula LO Lopes LV | 2005 | Epilepsia2005，46，： | 1 |
| 9 | Integrin β3 links therapy resistance and cancer stem cell properties显示文摘 | Kannan N Nguyen LV Eaves CJ | 2014 | Nat Cell Biol2014，16，5： | 1 |
| 10 | Diastolic stiffness of the failing diabetic heart importance of fibrosis, advanced glycation end products, and myocyte resting tension 显示文摘 | Heerebeek LV Hamdani N Handoko L | 2008 | Circulation2008，117，1： | 1 |
| 11 | Magnetic susceptibility of modern soil in China and climate conditions显示文摘 | HAN J M LV H Y WU N Q | 1996 | Studia Geophysical Geodetica1996，40，： | 1 |
| 12 | Association between lipoprotein- associated phospholipase A2 gene polymorphism and coronary artery disease in the Chinese Han population 显示文摘 | Li L Qi L Lv N | 2011 | Ann Hum Genet2011，75，5： | 1 |
| 13 | Antiobesity activity of aqueous extracts of Rhizoma Dioscoreae Tokoronis on high-fat diet-induced obesity in mice显示文摘 | Song M Y Lv N Kim E K | 2009 | Med Food2009，12，2： | 1 |
| 14 | Immunohistochemical identification of tissue factor in solid tumors显示文摘 | Callander NS Varki N Rao LV | 1992 | Cancer1992，70，5： | 1 |
| 15 | Cocaine- and amphetamine-regulated transcript (CART) acceler- ates the temination of FSH induced ERK1/2 and AKT aetivation by regulating the expression and deg- radation of specific MAP kinase phosphatases显示文摘 | ARITRO S LV L H BELLO N | 2008 | Mol Endocrinol2008，，22： | 1 |
| 16 | Soy protein adhesives improved by SiO2 nanoparticles for plywoods显示文摘 | Xu H N Ma S F Lv W P | 2011 | Pigment & Resin Technology2011，40，3： | 1 |
| 17 | Temperature and doping-dependent resistivity of Ti/Au/Pd/Au multiplayer ohmic contact to n-GaN显示文摘 | LU C Z CHEN H N LV X L | 2002 | Journal of Applied Hysics2002，91，11： | 1 |
| 18 | Eutectic mixtures of capric acid and lauric acid applied in building wallboards for heat energy storage显示文摘 | Lv S L Zhu N Feng G H | 2006 | Energy and Buildings2006，38，6： | 1 |
| 19 | Gemcitabine plus vinorelbine versus vinorelbine alone in elderly patients with advanced non-small-cell lung cancer 显示文摘 | Frasci G LV Panza N Comella P | 2000 | J Clin Oncol2000，18，： | 1 |
| 20 | Phase HI study of afa- tinib or cisplatin plus pemetrexed in patients with metastatic lung adenocarcinoma with EGFR mutations 显示文摘 | Sequist LV Yang JC Yamamoto N | 2013 | Journal of Clinical On- cology2013，31，27： | 1 |
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