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| 1 | Cost-utility of molecular adsorbent recirculating system treatment in acute liver failure显示文摘AIM:To determine the short-term cost-utility of mo-lecular adsorbent recirculating system(MARS) treatment in acute liver failure(ALF).METHODS:A controlled retrospective study was conducted with 90 ALF patients treated with MARS from 2001 to 2005.Comparisons were made with a historical control group of 17 ALF patients treated from 2000 to 2001 in the same intensive care unit(ICU) specializing in liver diseases.The 3-year outcomes and number of liver transplantations were recorded.All direct liver disease-related medical expenses from 6 mo before to 3 years after ICU treatment were determined for 31 MARS patients and 16 control patients.The health-related quality of life(HRQoL) before MARS treatment was estimated by a panel of ICU doctors and after MARS using a mailed 15D(15-dimensional generic healthrelated quality of life instrument) questionnaire.The HRQoL,cost,and survival data were combined and the incremental cost/quality-adjusted life years(QALYs) was calculated.RESULTS:In surviving ALF patients,the health-related quality of life after treatmeant was generally high and comparable to the age-and gender-matched general Finnish population.Compared to the controls,the average cost per QALY was considerably lower in the MARS group(64 732€ vs 133 858€) within a timeframe of 3.5 years.The incremental cost of standard medical treatment alone compared to MARS was 10 928€,and the incremental number of QALYs gained by MARS was 0.66.CONCLUSION:MARS treatment combined with standard medical treatment for ALF in an ICU setting is more cost-effective than standard medical treatment alone. | Taru Kantola Suvi Mklin Anna-Maria Koivusalo Pirjo Rsnen Anne Rissanen Risto Roine Harri Sintonen Krister Hckerstedt Helena Isoniemi | 2010 | World Journal of Gastroenterology2010，16，18： | 3 |
| 2 | Randomised comparison of combined step-down prednisolone, methotrexate and sulphasalazine with sulphasalazine alone in early rheumatoid arthritis显示文摘 | Maarten Boers Arco C Verhoeven Harry M Markusse Mart AFJ van de Laar Rene Westhovens J Christiaan van Denderen Derkjen van Zeben Ben AC Dijkmans Andre J Peeters Piet Jacobs Hans R van den Brink Hubert JA Schouten Désirée MFM van der Heijde Annelies Boonen | 1997 | The Lancet1997，，9074： | 1 |
| 3 | The impact of transportation infrastructure on bicycling injuries and crashes: a review of the literature 显示文摘 | Conor CO Reynolds M Anne Harris Kay Teschke Peter A Cripton Meghan Winters | 2009 | Environmental Health2009，8，： | 1 |
| 4 | Revaccination of healthy nonresponders with hepatitis B vaccine and prediction of seroprotection response显示文摘 | Myong-Jin Kim Anne N Nafziger Clayton D Harro Harry L Keyserling Keith M Ramsey George L Drusano Joseph S Bertino | 2002 | Vaccine2002，，11： | 1 |
| 5 | Effects of teacher clarity and student anxiety on student outcomes显示文摘 | Susan R Harry G M Anne L C | | 0，，01： | 1 |
| 6 | Inflammatory markers and cardiovascular disease (The Health, Aging and Body Composition [Health ABC] Study)显示文摘 | Matteo Cesari Brenda W.J.H Penninx Anne B Newman Stephen B Kritchevsky Barbara J Nicklas Kim Sutton-Tyrrell Russell P Tracy Susan M Rubin Tamara B Harris Marco Pahor | 2003 | The American Journal of Cardiology2003，，5： | 1 |
| 7 | Patient perceptions of stool DNA testing for pan-digestive cancer screening:A survey questionnaire显示文摘AIM:To explore patient interest in a potential multiorgan stool-DNA test(MUST)for pan-digestive cancer screening.METHODS:A questionnaire was designed and mailed to 1200 randomly-selected patients from the Mayo Clinic registry.The 29-item survey questionnaire included items related to demographics,knowledge of digestive cancers,personal and family history of cancer,personal concern of cancer,colorectal cancer(CRC)screening behavior,interest in MUST,importance of test features in a cancer screening tool,and comparison of MUST with available CRC screening tests.All responses were summarized descriptively.χ2 and Rank Sum Test were used for categorical and continuous variables,respectively.RESULTS:Completed surveys were returned by 434(29%aged 50-59,37%60-69,34%70-79,52%women).Most participants(98%)responded they would use MUST.In order of importance,respondents rated multicancer detection,absence of bowel preparation,safety and noninvasiveness as most attractive characteristics.For CRC screening,MUST was preferred over colorectal-only stool-DNA testing(53%),occult blood testing(75%),colonoscopy(84%),sigmoidoscopy(91%),and barium enema(95%),P<0.0001 for each.Among those not previously screened,most(96%)indicated they would use MUST if available.Respondents were confident in their ability to follow instructions to perform MUST(98%).Only 9%of respondents indicated that fear of finding cancer was a concern with MUST,and only 3%indicated unpleasantness of stool sampling as a potential barrier.CONCLUSION:Patients are receptive to the concept of MUST,preferred MUST over conventional CRC screening modalities and valued its potential feature of multi-cancer detection. | Dennis Yang Shauna L Hillman Ann M Harris Pamela S Sinicrope Mary E Devens David A Ahlquist | 2014 | World Journal of Gastroenterology2014，20，17： | 1 |
| 8 | Social physique anxiety and eating attitudes in female athletic and non-athletic groups显示文摘 | ANNE M HASE HARRY PRAPAVESSLS | 2002 | Soc Physique Anxiety Eating Attitudes2002，18，9： | 1 |
| 9 | Silicone oil in the repair of complex retinal detachments显示文摘 | Stanley P Azen Ingrid U Scott Harry W Flynn Mei-Ying Lai Trexler M Topping Lisa Benati Douglas K Trask Lee Ann Rogus | 1998 | Ophthalmology1998，，9： | 1 |
| 10 | DNA Deamination Mediates Innate Immunity to Retroviral Infection显示文摘 | Reuben S Harris Kate N Bishop Ann M Sheehy Heather M Craig Svend K Petersen-Mahrt Ian N Watt Michael S Neuberger Michael H Malim | 2003 | Cell2003，，6： | 1 |
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