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1Predictive factors for anastomotic leakage after laparoscopic colorectal surgery显示文摘Every colorectal surgeon during his or her career is faced with anastomotic leakage(AL); one of the most dreaded complications following any type of gastrointestinal anastomosis due to increased risk of morbidity, mortality, overall impact on functional and oncologic outcome and drainage on hospital resources. In order to understand and give an overview of the AL risk factors in laparoscopic colorectal surgery, we carried out a careful review of the existing literature on this topic and found several different definitions of AL which leads us to believe that the lack of a consensual, standard definition can partly explain the considerable variations in reported rates of AL in clinical studies. Colorectal leak rates have been found to vary depending on the anatomic location of the anastomosis with reported incidence rates ranging from 0 to 20%, while the laparoscopic approach to colorectal resections has not yet been associated with a significant reduction in AL incidence. As well, numerous risk factors, though identified, lack unanimous recognition amongst researchers. For example, the majority of papers describe the risk factors for left-sided anastomosis, the principal risk being male sex and lower anastomosis, while little data exists defining AL risk factors in a right colectomy. Also, gut microbioma is gaining an emerging role as potential risk factor for leakage.Antonio Sciuto Giovanni Merola Giovanni D De Palma Maurizio Sodo Felice Pirozzi Umberto M Bracale Umberto Bracale 2018World Journal of Gastroenterology2018,24,21:48
2Decreased expression of Klotho in cardiac atria biopsy samples from patients at higher risk of atherosclerotic cardiovascular disease显示文摘BackgroundKlotho 蛋白质(α - 并且 β) 是基于膜的传播调整细胞新陈代谢的蛋白质,以及成纤维细胞生长因素(FGF ) 的 lifespan modulating 活动。最近的数据证明了更高的血浆传播 Klotho 层次减少心血管的风险,建议 Klotho 有在心血管的疾病的一个保护的角色。然而,尽管到目前为止它在各种各样的机关被识别了,它是未知的是否,并且高心血管的风险是否能影响 Klotho 的心脏的表示 cardiomyocytes 快车 Klotho 和 FGF , FGF 和另外的 molecules.MethodsWe 与心血管的疾病和 10 匹配年龄的控制使遭到,估计的10年的低风险经历的一名估计的10年的高动脉粥样硬化患者选择了 20 个病人为除冠的动脉以外的原因的心脏的外科绕过。在心肌的活体检视,我们由免疫组织化学评估了 Klotho 和 FGF 是否在 cardiomyocytes 被表示,并且更高心血管的风险是否影响涉及 endoplasmic 蜂窝胃应力的另外的分子的表示,氧化应力,发炎并且 fibrosis.ResultsOnly ,有更高心血管的风险的病人的 cardiomyocytes 显示出 Klotho 的更低的表示,但是 FGF 的更高的表情。而且,更高心血管的风险与增加的表示被联系氧化并且网状的应力,发炎和 fibrosis.ConclusionsThis 学习的 endoplasmic 第一次证明 Klotho 蛋白质在人的 cardiomyocytes 被表示, Klotho 的那心脏的表情在更高心血管的风险病人是下面调整的,当压力相关的分子的表示显著地被增加时。Giovanni Corsetti Evasio Pasini Tiziano M Scarabelli Claudia Romano Pratik R Agrawal Carol Chen-Scarabelli Richard Knight Louis Saravolatz Jagat Narula Mario Ferrari-Vivaldi Vincenzo Flati Deodato Assanelli Francesco S Dioguardi 2016Journal of Geriatric Cardiology2016,13,8:7
3Impact of laparoscopic surgery training laboratory on surgeon's performance显示文摘Minimally invasive surgery has been replacing the open standard technique in several procedures. Similar or even better postoperative outcomes have been described in laparoscopic or robot-assisted procedures when compared to open surgery. Moreover, minimally invasive surgery has been providing less postoperative pain, shorter hospitalization, and thus a faster return to daily activities. However, the learning curve required to obtain laparoscopic expertise has been a barrier in laparoscopic spreading. Laparoscopic surgery training laboratory has been developed to aid surgeons to overcome the challenging learning curve. It may include tutorials, inanimate model skills training(box models and virtual reality simulators), animal laboratory, and operating room observation. Several different laparoscopic courses are available with specific characteristics and goals. Herein, we aim to describe the activities performed in a dry and animal-model training laboratory and to evaluate the impact of different kinds of laparoscopic surgery training courses on surgeon's performance. Several tasks are performed in dry and animal laboratory to reproduce a real surgery. A short period of training can improve laparoscopic surgical skills, although most of times it is not enough to confer laparoscopic expertise for participants. Nevertheless, this short period of training is able to increase the laparoscopic practice of surgeons in their communities. Full laparoscopic training in medical residence or fellowship programs is the best way of stimulating laparoscopic dissemination.Fabio C M Torricelli Joao Arthur B A Barbosa Giovanni S Marchini 2016World Journal of Gastrointestinal Surgery2016,8,11:6
4Enteric neuropathology of congenital intestinal obstruction:A case report显示文摘试验性的证据显示肠的长期的机械亚吸藏可以损坏伤寒神经系统(ENS ) ,尽管在人的数据正在缺乏。我们这里描述伤寒的第一诉讼与内脏的先天的阻塞有关的退化神经病。3 年的 A 和老女孩开始抱怨了呕吐的 9 瞬间,腹的扩张,有空气液体的便秘在飞机铺平腹的辐射学。她的随后的病历被 3 操作描绘:首先显示出的扩大 duodeno-jejunal 当闭塞的损害不在时循环;第二(2 年以后) 被执行获得扩大的肠的环的完整厚度的活体检视并且在组织病理学说揭示了 hyperganglionosis;第三(在 hyperganglionosis 以后的 9 年被识别) 揭示了 Ladd 被移开的乐队,联系内脏旋转不良被改正。完整厚度的活体检视显示出的重复 intraoperative 与 Cajal 的减少的空隙的房间一起的退化神经病在 Ladd 的乐队下面在阻塞和正常的神经与肌的层上面在扩大的环联网的伤寒。病人容忍了的在最近的外科以后的一年口头的喂并且很好,建议那先天(部分) 在人的小肠的机械阻塞能唤起类似于在肠的机械吸藏的动物模型发现的那些的 ENS 的进步适应变化。如此的 ENS 变化模仿在肠的伪阻塞观察的神经元畸形。Giovanni Di Nardo Vincenzo Stanghellini Salvatore Cucchiara Giovanni Barbara Gianandrea Pasquinelli Donatella Santini Cristina Felicani Gianluca Grazi Antonio D Pinna Rosanna Cogliandro Cesare Cremon Alessandra Gori Roberto Corinaldesi Kenton M Sanders Roberto De Giorgio 2006World Journal of Gastroenterology2006,12,32:4
5Leader behaviors and the work environment for creativity: Perceived leader support显示文摘Teresa M Amabile Elizabeth A Schatzel Giovanni B Moneta Steven J Kramer 2004The Leadership Quarterly2004,,1:2
6l -Carnitine: An adequate supplement for a multi-targeted anti-wasting therapy in cancer显示文摘Sílvia Busquets Roberto Serpe Míriam Toledo Angélica Betancourt Enrica Marmonti Marcel Orpí Fabrizio Pin Eva Capdevila Clelia Madeddu Francisco J. López-Soriano Giovanni Mantovani Antonio Macciò Josep M. Argilés 2012Clinical Nutrition2012,,6:2
7Water-immersion Technique During Standard Upper Endoscopy May Be Useful to Drive the Biopsy Sampling of Duodenal Mucosa in Children With Celiac Disease显示文摘Giovanni Cammarota Alessia Cazzato Orazio Genovese Adriano Pantanella Gianluca Ianiro Valentina Giorgio Massimo Montalto Fabio M Vecchio Luigi M Larocca Giovanni Gasbarrini Carlo Fundarò 2009Journal of Pediatric Gastroenterology and Nutrition2009,,4:2
8Role of rumination in the relationship between metacognition and shyness显示文摘AIM To explore the association between metacognitive beliefs, rumination and shyness in a non-clinical sample of adults. METHODS One hundred and three healthy subjects from the general population were enrolled in the study. Shyness was evaluated using the Revised Cheek and Buss Shyness Scale, rumination was assessed using the Ruminative Response Scale, metacognition was evaluated using the MetaCognitions Questionnaire 30, and anxiety levels were measured using the State Trait Anxiety Inventory form Y. Correlation analyses, mediation models and 95% bias-corrected and accelerated(BCaCI) bootstrapped analyses were performed. Mediation analyses were adjusted for sex and anxiety. RESULTS Shyness, rumination and metacognition were significantly correlated(P < 0.05). The relationship between metacognition and shyness was fully mediated by rumination(Indirect effect: 0.20; 95% BCaCI: 0.08-0.33).CONCLUSION These findings suggest an association between metacognition and shyness. Rumination mediated the relationship between metacognition and shyness, suggesting that rumination could be a cognitive strategy for shy people. Future research should explore the relationship between these constructs in more depth.Sara Palmieri Giovanni Mansueto Simona Scaini Francesca Fiore Sandra Sassaroli Giovanni M Ruggiero Rosita Borlimi Bernardo J Carducci 2018World Journal of Psychiatry2018,8,4:2
9Nocturnal Hypoxemia Predicts Incident Cardiovascular Complications in Dialysis Patients显示文摘Carmine Z Francesca M Giovanni T 2002J Am Soc Nephrol2002,13,:1
10First experiencewith gemtuzumab ozogamicin plus cytarabine as continuousinfusion for elderly acute myeloid leukaemia patients显示文摘Pier P P Giovanni M Michela R 2004Leuk Res2004,28,:1
11Spent filter backwash water contaminants and treatment strategies显示文摘Arora tt Di Giovanni G LeChevallier M 2001American Water Works Association2001,,10:1
12Cozart Rapiscan system:our experience with saliva tests显示文摘De Giovanni N Fucci N Chiarotti M 2002J Chromatogr B A nalyt Technol Biomed Life Sci2002,773,1:1
13Timestamps in key distribution protocols 显示文摘DOROTHY E D GIOVANNI M S 1981Communication of the ACM1981,24,8:1
14Phylogenetic analysis of partial S1 and N gene sequences of infectious bronchitis virus isolates from Italy revealed genetic diversity and recombination显示文摘YURY A B GIOVANNI T PAOLA M 2007Virus Genes2007,35,:1
15New Design Approach for Steel Fiber-reinforced Concrete Slabs-on-ground Based on Fracture Mechanics显示文摘Alberto M Giovanni A P 2004ACI Structural Journal2004,101,3:1
16Comparative study of aro-ma profile and content of Montepulciano monovarietal red wines fromthe Marches and Abruzzo regions of Italy using HS-SPME-GC-MS andHPLC-MS显示文摘GIANNI S FILIPPO M GIOVANNI C 2012Food Chem2012,132,3:1
17Identification ofmicrosatellite markers for fragrance in rice by analysis of the rice genome sequence 显示文摘Giovanni M Cordeiro Mandy J Christopher Robert J Henry 2002Molecular Breeding2002,9,4:1
18Proliferating cell nuclear antigen(PCNA):a d-ancerwithmanypartners显示文摘Giovanni M Ulrich H 2003JournalofCellScience2003,116,15:1
19Diagnostic accuracy of the Anti-citrulline Antibody assay for rheumatoid arthritis 显示文摘Nicola B Giovanni M Elio T 2001Clin chem2001,47,:1
20New targets for Ph+ leukaemia therapy显示文摘Giovanni M Ilaria I Cristina P 2009Best Pract Res Clin Haematol2009,22,3:1
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