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| 1 | Leptin levels in the differential diagnosis between benign and malignant ascites显示文摘AIM: To evaluate the role of leptin levels in the differential diagnosis of ascites. METHODS: Ascitic leptin, TNFα and serum leptin levels were measured in 77 patients with ascites (35 with malignancies, 30 cirrhosis and 12 tuberculosis). Control serum samples were obtained from 20 healthy subjects. Leptin and TNFα levels were measured by ELISA. Body mass index (BMI) and percentage of body fat (BFM) by skin fold measurement were calculated for all patients and control groups. Peritoneal biopsy, ascites cytology and cultures or biochemical values were used for the diagnosis of patients. RESULTS: In patients with malignancies, the mean serum and ascites leptin levels and their ratios were significantly decreased compared to the other patient groups and controls. In tuberculosis peritonitis, ascitic fluid TNFα levels were significantly higher than malignant ascites and cirrhotic sterile ascites. BMI and BFM values did not distinguish between patients and controls. CONCLUSION: In patients with malignant ascites, levels of leptin and TNFα were significantly lower than in patients with tuberculous ascites. | Mehmet Buyukberber Mehmet Koruk M Cemil Savas Murat T Gulsen Yavuz Pehlivan Rukiye Deveci Alper Sevinc Serdar Gergerlioglu | 2007 | World Journal of Gastroenterology2007，13，3： | 7 |
| 2 | Early detection of response to imatinib therapy for gastrointestinal stromal tumor by using 18F-FDG-positron emission tomography and computed tomography imaging显示文摘有变形胃肠的基质肿瘤的 41 年的老女性被指 18F-FDG-positron 排放断层摄影术和计算断层摄影术(PET/CT ) 与 imatinib 在一个月前后扫描治疗(Glivec 收款机, Gleevec 收款机, Novartis,巴塞尔,瑞士) ,一个酷氨酸激酶禁止者(400 mg/d ) 。新陈代谢的反应在一月治疗前后被评估。最大的 standardised 举起价值(SUV ) 的减少是 79%( 从 9.8 ~ 2.1 ) 。正电子排放断层摄影术在 imatinib 治疗的一个月以后表明了完全的新陈代谢的反应。另外,以前的损害与花冠相比是计算机化的 tomographic 图象。根据 CT 图象在在治疗前后的肿瘤的尺寸没有差别。然而,新陈代谢的活动被禁止。18F-FDG-PET 是为对在有胃肠的基质肿瘤的病人的一个月 imatinib 治疗的反应的察觉的一个珍贵方法。 | Sabri Zincirkeser Alper Sevinc M Emin Kalender Celalettin Camci | 2007 | World Journal of Gastroenterology2007，13，15： | 7 |
| 3 | Effect of sunitinib on metastatic gastrointestinal stromal tumor in patients with neurofibromatosis type 1: A case report显示文摘Gastrointestinal stromal tumor (GIST) represents the most common mesenchymal malignancy of the gastrointestinal (GI) tract. In neurofibromatosis (NF), the increased incidence of tumor needs to be considered even in non-symptomatic individuals. Patients with neurofibromatosis NF type 1 have an increased risk of developing GI tumors including rare types such as GIST. We report a case of GIST in a 53-year-old male patient with neurofibromatosis. The patient was diagnosed with NF four years ago and his medical history revealed that he was hospitalized 5 times with a provisional diagnosis of massive lower gastrointestinal bleeding. GIST was diagnosed at explorative laparotomy and the tumor was 21 cm × 13 cm × 7 cm in size. Immunohistochemical examination showed that vimentin, actin and CD117 were positive. Computerized tomography showed peritoneal implants three months later. Imatinib mesylate (600 mg/d) was initiated. However, control computerized tomography revealed liver and omental metastasis. The dosage was elevated to 800 mg/d. Despite high dosage, the progression of the metastatic lesions continued in the liver and omentum. The patient started oral sunitinib malate (Sutent? Pfizer Inc, New York, NY, USA) 50 mg per day for 4 consecutive weeks, followed by 2 wk off per treatment cycle. The metastatic lesions in the liver and omentum were decreased in size after four courses, suggesting that sunitinib is also an effective treatment modality for metastatic GIST in NF patients. | M Emin Kalender Alper Sevinc Ediz Tutar Akif Sirikci Celalettin Camci | 2007 | World Journal of Gastroenterology2007，13，18： | 5 |
| 4 | Lipid and lipo- protein levels in dairy cows with fatty liver 显示文摘 | M Sevinc A Basuglu H Guzelbektas | 2009 | Turkish Journal of Veterinary and Animal Sciences2009，27，2： | 1 |
| 5 | The clinical chemical parameters, serum lipoproteins and fatty infiltration of the liver in ketotic cows显示文摘 | SEVINC M BASOGLU A OZTOK I | 1998 | Turkish J Vet Anita Sci1998，，22： | 1 |
| 6 | The effect of calcination temperature on some of the adsorptive properties of fine alumina powders obtained by emulsion evaporation tech- nique 显示文摘 | Sarikaya Y Sevinc I Akinc M | 2001 | Powder Technology2001，116，： | 1 |
| 7 | Benign causes ofincreased serum CA125 concentration显示文摘 | Sevinc A Adli M Kalender ME | 2007 | Lancet Oncol2007，8，12： | 1 |
| 8 | Female adnexal tumor of probable Wolffian origin diagnosed during the staging evaluation of extranodal diffuse large B-cell lymphoma显示文摘 | Karaca M Sevinc A Aydin A | 2005 | Leuk Lymphoma2005，46，6： | 1 |
| 9 | Irinotecan as a second-line monotherapy for small cell lung cancer显示文摘 | Sevinc A Kalender ME Altinbas M | 2011 | Asian Pac J Cancer Prev2011，12，4： | 1 |
| 10 | Prevention of oral mu- cositis due to 5-fluorouracil treatment with oral cryotherapy 显示文摘 | Baydar M Dikilitas M Sevinc A | 2005 | J Natl Med Assoc2005，97，8： | 1 |
| 11 | LIGHTNETs: smart lighting and mobile optical wireless networks--a survey 显示文摘 | SEVINCER A BHATTARAI A BILGI M | 2013 | IEEE Communications Surveys and Tutorials2013，15，4： | 1 |
| 12 | Babesia ovis infections:detailed clinical and laboratory observations in the pre-and post-treatment periods of 97 field cases显示文摘 | Sevinc F Sevinc M Ekici OD | | 0，，1： | 1 |
| 13 | Fatty liver in periparturient diseases of dairy cows显示文摘 | Sevinc M Bzsoglu A Ok M | 2002 | Indian Veterinary Journal2002，79，12： | 1 |
| 14 | 2000, Erythrocyte Measure- ments in Lacerta rudis (Reptilia, Lacertidae) 显示文摘 | Sevinc M Ugurtas IH Yi|dirimhan HS | 2000 | Turkish Journal of Zoology2000，24，2： | 1 |
| 15 | Benign causes of increased serum CA 125 concentration显示文摘 | Sevinc A Adili M Kalender ME Camci C | 2007 | Lancet Oncol2007，8，12： | 1 |
| 16 | The thickness of the ligamentum flavum in relation to age and gender 显示文摘 | Safak AA Is M Sevinc O | 2010 | Clin Anat2010，23，1： | 1 |
| 17 | How to interpret serum CA125 levels in patients with serosal involvement? A clinical dilemma显示文摘 | SEVINC A CAMCI C TURK H M | 2003 | Oncology2003，65，1： | 1 |
| 18 | Scar endometriosis in the abdominal wall:a predictable condition for experienced surgeons显示文摘 | AKBULUT S SEVINC M M BAKIR S | 2010 | Acta Chir Belg2010，110，3： | 1 |
| 19 | The thickness of the ligamentum flavum in relation to age and gender显示文摘 | Safak A Is M Sevinc O | 2010 | Clin Anat2010，23，1： | 1 |
| 20 | Increased oxidative stress in children exposed to passive smoking显示文摘 | KOSECIK M EREL O SEVINC E | 2005 | Int J Cardiol2005，100，1： | 1 |
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