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4篇 您的检索式:作者名="M.Arce"
    题名 作者 年代 出处 被引量
1The Dilemma of the Prisoners’ Dilemmas显示文摘G.Daniel M.Arce ToddSandler 2005Kyklos2005,,1:1
2New insights into the relevance of mobile DNA to cancer resistance in blind mole rats:new lessons for cancer therapy显示文摘Although mammals differ substantially in their cancer incidence rates and in the importance of age as a cancer risk factor,there is a scaling of cancer incidence to the lifespan in most species.Animal evolution has selected strategies that maximize reproductive success,which include the development of efficient mechanisms to defer the initiation of cancer until postreproductive age[1].Owing to this,cancers are very rare among wild animals(which do not typically live beyond their reproductive ages).Victor M.Arce Jose A.Costoya 2022Cellular & Molecular Immunology2022,19,4:0
3SARS-CoV-2 infection in K18-ACE2 transgenic mice replicates human pulmonary disease in COVID-19显示文摘Over the last several months,a global pandemic has developed due to the emergence of the novel severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),which is capable of infecting humans.The lack of preexisting immunity to SARSCoV-2 in humans has prompted the scientific community to strive to understand the mechanisms underlying SARS-CoV-2 pathogenesis and to test new therapeutic agents and vaccines for the clinical management of coronavirus disease 2019(COVID-19).In these efforts,the development of appropriate animal models of the disease is one of the most valuable strategies.Victor M.Arce Jose A.Costoya 2021Cellular & Molecular Immunology2021,18,3:0
4Cancer cells escape the immune system by increasing stemness through epigenetic reprogramming显示文摘Cancer stem cells(CSCs),also known as tumor initiating cells,are a minority subpopulation of undifferentiated cancerous cells within the entire tumor that hold self-renewal capacity and differentiation potential.CSCs are critical for tumor progression,heterogeneity and metastasis and play a major role in chemo-and radiation-resistance and tumor recurrence[1].Although the molecular mechanisms underlying the ability of CSCs to give rise to new tumors and promote resistance to many cancer therapies are not completely understood,increasing knowledge suggests potential roles for these cells in the evasion of immune surveillance[2,3].Jose A.Costoya Victor M.Arce 2023Cellular & Molecular Immunology2023,20,1:0
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