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4篇 您的检索式:作者名="M.Kaufman"
    题名 作者 年代 出处 被引量
1The mannose‐binding lectin gene polymorphisms and systemic lupus erythematosus: Two case–control studies and a meta‐analysis显示文摘YoungHo Lee TorstenWitte TanjaMomot Reinhold E.Schmidt Kenneth M.Kaufman John B.Harley Andrea L.Sestak 2005Arthritis & Rheumatism2005,,:1
2Late‐onset celecoxib‐induced combined hepato‐nephrotoxicity显示文摘James H.Tabibian NeshanTabibian David M.Kaufman 2008British Journal of Clinical Pharmacology2008,,1:1
3预防性输入血小板的剂量和出血的预防显示文摘背景我们对再生障碍性贫血患者预防性输入血小板进行试验,用以评价血小板剂量对出血的影响。方法我们将患血癌或实体瘤做过造血干细胞移植或化疗的住院患者随机分组,当患者晨间血小板计数≤10000/mm3时,分别输入小剂量、中剂量或大剂量血小板(1.1×1011,2.2×1011,或4.4×1011血小板/m2体表面积)。每天做临床出血征评估。主要终点为≥2级(基于WHO标准)出血。结果其中有1272例患者至少接受了1次血小板输入,小剂量、中剂量和大剂量组所观察到的主要终点分别为71%、69%和70%(无显著差异)。较高级别出血和其他负性事件发生率3组相似。输入血小板中位数,小剂量组(9.25×1011)明显低于中剂量组(11.25×1011)或大剂量组(19.63×1011)(小剂量组与中剂量组相比,P=0.002;大剂量组与小剂量组相比,大剂量组和中剂量组相比,P<0.001),但低剂量组血小板输入中位次数明显要多(5次对中剂量组3次和大剂量组3次;小剂量组与中剂量组相比和小剂量与大剂量组相比,P<0.001)。研究期间,晨间血小板计数为≤5000/mm3出血发生率为25%,若血小板计数在6000~80000/mm3,出血发生率17%(P<0.001)。结论预防性输入小剂量血小板可减少每例患者血小板的输入数目,但增加了输入次数。当剂量在1.1×1011~4.4×1011血小板/m2时,预防性输入并不影响出血率。Sherrill J.Slichter Richard M.Kaufman Susan F.Assmann 周淑新(译) 2010中国全科医学2010,13,31:0
4Angling of hybrid sunfish from a hatchery pond with potential implications for community fisheries显示文摘Hatcheries are frequently called upon to produce catchable-sized fish for stocking community fishing ponds.Desirable attributes of fish selected for stocking into community ponds are that they are easy to produce in a hatchery system to sizes anglers are interested in catching and they provide anglers with high catch rates once stocked.Hybrid sunfish[male Bluegill(Lepomis macrochirus)×female Green Sunfish(L.cyanellus)]have attributes that potentially make them attractive for use in community fishing ponds.We assessed initial angler catch rates of 100 stocked hybrid sunfish in a 0.12-ha hatchery pond and after being subjected to angling(four,1-hr catch-and-release fishing events with five anglers).We also investigated whether catch rates would change following a supplemental stocking of an additional 100 hybrid sunfish(four,1-hr catch-and-release fishing events with five anglers).The anal fin of each fish in the second stocking was hole punched to differentiate them from those of the first stocking and fish caught by anglers were hole punched in the caudal fin each time they were caught before being released back into the pond.Angler catch rates were highest during initial fishing events that followed stocking(9.2 fish/angler hr and 18.0 fish/angler hr)and substantially declined in subsequent events(≤3.4 fish/angler hr).Catches of the newly stocked fish and previously stocked fish contributed to the high catch following the supplemental stocking.Most(80%)of the fish were caught in the first 30 min of each event and 45%were caught during the first 10 min.Anglers were able to catch 88%of the fish from the first stocking and 67%from the second stocking at least once.No mortality occurred during the study as all fish were recovered when the pond was drained.Our results suggest that hybrid sunfish will potentially provide high initial catch rates following stocking into community ponds,but managers should expect reduced catch rates following initial fishing even without harvest.Additional stocking will be needed to provide periodic increases in angler catch rates even without harvest.Brian G.Blackwell Matthew J.Ward Todd M.Kaufman 2023Aquaculture and Fisheries2023,8,1:0
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