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| 1 | Validation of a new scoring system: Rapid assessment faecal incontinence score显示文摘AIM: To implement a quick and simple test- rapid assessment faecal incontinence score(RAFIS) and show its reliability and validity.METHODS: From March 2008 through March 2010, we evaluated a total of 261 consecutive patients, including 53 patients with faecal incontinence. Demographic and comorbidity information was collected. In a single visit, patients were administered the RAFIS. The results obtained with the new score were compared with those of both Wexner score and faecal incontinence quality of life scale(FIQL) questionnaire. The patient withoutinfluence of the surgeon completed the test. The role of surgeon was explaining the meaning of each section and how he had to fill. Reliability of the RAFIS score was measured using intra-observer agreement and Cronbach's alpha(internal consistency) coefficient. Multivariate analysis of the main components within the different scores was performed in order to determine whether all the scores measured the same factor and to conclude whether the information could be encompassed in a single factor. A sample size of 50 patients with faecal incontinence was estimated to be enough to detect a correlation of 0.55 or better at 5% level of significance with 80% power.RESULTS: We analysed the results obtained by 53 consecutive patients with faecal incontinence(median age 61.55 ± 12.49 years) in the three scoring systems. A total of 208 healthy volunteers(median age 58.41 ± 18.41 years) without faecal incontinence were included in the study as negative controls. Pearson's correlation coefficient between 'state' and 'leaks' was excellent(r = 0.92, P < 0.005). Internal consistency in the comparison of 'state' and 'leaks' yielded also excellent correlation(Cronbach's α = 0.93). Results in each score were compared using regression analysis and a correlation value of r = 0.98 was obtained with Wexner score. As regards FIQL questionnaire, the values of 'r ' for the different subscales of the questionnaire were: 'lifestyle' r =-0.87, 'coping/behaviour' r =-0.91, 'depression' r =-0.36 and 'embarrassment' r =-0.90,(P < 0.01). A multivariate analysis showed that all the scoring systems measured the same factor. A single factor may explain 80.84% of the variability of FI, so all the scoring systems measure the same factor. Patient's continence improves when RAFIS and Jorge-Wexner scores show low values and when the values obtained in the FIQL questionnaire are high.CONCLUSION: RAFIS is a valid and reliable tool to assess Faecal Incontinence. | Fernando de la Portilla Arantxa Calero-Lillo Rosa M Jiménez-Rodríguez Maria L Reyes Manuela Segovia-González María Victoria Maestre Ana M García-Cabrera | 2015 | World Journal of Gastrointestinal Surgery2015，7，9： | 5 |
| 2 | Analysis of FOXP3 protein expression in human CD4+ CD25+ regulatory T cells at the single-cell level显示文摘 | Brown PJ Maestre L | 2005 | Eur J Immunol2005，35，6： | 1 |
| 3 | Analysis of FOXP3 protein expression in human CD4 + CD25 + regulatory T ceils at the single-cell level 显示文摘 | Roncador G Brown PJ Maestre L | 2005 | EurJImmunol2005，35，6： | 1 |
| 4 | Analysis of FOXP3 pro- tein expression in human CD4+ CD25 + regulatory T ceils at the single-cell level 显示文摘 | Roneador G Brown PJ Maestre L | 2005 | Eur J Immunol2005，35，6： | 1 |
| 5 | Tilted implants for the restoration of posterior mandibles with horizontal atrophy:an alternative treatment显示文摘 | Pe arrocha Diago M Maestre Fen'in L | 2013 | J Oral Maxillofac Surg2013，71，5： | 1 |
| 6 | Expression pattern of XBP1 (S) in human B-cell lymphomas 显示文摘 | Maestre L Tooze R Cafiamero M | 2009 | Haematologica2009，94，3： | 1 |
| 7 | Analysis of FOXP3 protein expression in human CD4( + )CD2S( +) regulatory T cells at the single-cell level显示文摘 | Roncador G Brown PJ Maestre L | 2005 | EurJ Imrnunol2005，35，： | 1 |
| 8 | Microsite differences in fungal hyphal length, glomalin, and soil aggregate stability in semiarid Mediterranean steppes显示文摘 | RILLIG M C MAESTRE F T LAMIT L J | 2003 | Soil Biology and Biochemistry2003，35，： | 1 |
| 9 | Analysis of FOXP3 protein expression in human CD4+CD25+regulatory T cells at the singlecell level显示文摘 | Roncador G Brown P J Maestre L | 2005 | Eur J Immunol2005，35，6： | 1 |
| 10 | Analysis of FOXP3 protein expression in human CD4^+ CD25^+ regulatory T cells at the single cell level显示文摘 | Roncador G Brown PJ Maestre L | 2005 | Eur J Immunol2005，35，6： | 1 |
| 11 | Use of butanol-watermixtures for making wheat straw pulp 显示文摘 | JIMNEZ L MAESTRE F PREZ I | 1999 | Wood Sci-ence and Technology1999，33，2： | 1 |
| 12 | Simultaneous detection of the immunophenotypic markers and genetic aberrations on routinely processed paraffin sections of lymphoma samples by means of the FICTION technique显示文摘 | Cigudosa JC Maestre L | 2004 | Leukemia2004，18，2： | 1 |
| 13 | FOXP3,a selective marker for a subset of adult T-cell leukaemia/lymphoma显示文摘 | Roncador G Garcia JF Maestre L Lucas E Menarquez J | | 0，，： | 1 |
| 14 | Microsite differences in fungal hyphal length, glomalin, and soil aggregate stability in semiarid Mediterranean steppes 显示文摘 | Rillig M C Maestre F T Lamit L J | 2003 | Soil Biology Biochemistry2003，35，： | 1 |
| 15 | A new continuous calibration method for inductively coupled plasma spectrometry 显示文摘 | zE Paredes S E Maestre J L Todol | 2006 | Anal Bioanal Chem2006，384，： | 1 |
| 16 | Strong slime production is a marker of clinical significance in Staphylococcus epidermidis isolated from intravascular catheters显示文摘 | Mateo M Maestre J R Aguilar L | 2008 | Eur J Clin Microbiol Infect Dis2008，27，4： | 1 |
| 17 | Analysis of FOXP3 protein expression in human CD^4+ CD25^+ regulatory T cells at the single cell level显示文摘 | Roncador C Brown P J Maestre L | 2005 | Eur J Immunol2005，35，6： | 1 |
| 18 | Microsite differences in fungal hyphal length, glomalin, and soil aggregate stability in semiarid Mediterranean steppes显示文摘 | Rillig M C Maestre F T Lamit L J | 2003 | Soil Biology and Biochemistry2003，35，： | 1 |
| 19 | Analysis of FOXP3 protein expression in human CD4^+ CD25^+ regulatory T cells at the single-cell level显示文摘 | Roncador G Brown PJ Maestre L | 2005 | Eur J Immunol2005，35，6： | 1 |
| 20 | Expression pattern of XBP1(S)in human B-cell lymphomas显示文摘 | MAESTRE L TOOZE R CANAMERO M | 2009 | Haematologica2009，94，3： | 1 |
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