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| 1 | Transcranial direct current stimulation in psychiatric disorders显示文摘The interest in non-invasive brain stimulation techniques is increasing in recent years. Among these techniques, transcranial direct current stimulation(t DCS) has been the subject of great interest among researchers because of its easiness to use, low cost, benign profile of side effects and encouraging results of research in the field. This interest has generated several studies and randomized clinical trials, particularly in psychiatry. In this review, we provide a summary of the development of the technique and its mechanism of action as well as a review of the methodological aspects of randomized clinical trials in psychiatry, including studies in affective disorders, schizophrenia, obsessive compulsive disorder, child psychiatry and substance use disorder. Finally,we provide an overview of t DCS use in cognitive enhancement as well as a discussion regarding its clinical use and regulatory and ethical issues. Although many promising results regarding t DCS efficacy were described, the total number of studies is still low, highlighting the need of further studies aiming to replicate these findings in larger samples as to provide a definite picture regarding t DCS efficacy in psychiatry. | Gabriel Tortella Roberta Casati Luana V M Aparicio Antonio Mantovani Natasha Senco Giordano D’Urso Jerome Brunelin Fabiana Guarienti Priscila Mara Lorencini Selingardi Débora Muszkat Bernardo de Sampaio Pereira Junior Leandro Valiengo Adriano H Moffa Marcel Simis Lucas Borrione André R Brunoni | 2015 | World Journal of Psychiatry2015,5,1: | 6 |
| 2 | Model combining pre-transplant tumor biomarkers and tumor size shows more utility in predicting hepatocellular carcinoma recurrence and survival than the BALAD models显示文摘AIM To assess the performance of BALAD, BALAD-2 and their component biomarkers in predicting outcome of hepatocellular carcinoma(HCC) patients after liver transplant.METHODS BALAD score and BALAD-2 class are derived from bilirubin, albumin, alpha-fetoprotein(AFP), Lens culinaris agglutinin-reactive AFP(AFP-L3), and des-gammacarboxyprothrombin(DCP). Pre-transplant AFP, AFP-L3 and DCP were measured in 113 patients transplanted for HCC from 2000 to 2008. Hazard ratios(HR) for recurrence and death were calculated. Univariate and multivariate regression analyses were conducted. C-statistics were used to compare biomarker-based to predictive models. RESULTS During a median follow-up of 12.2 years, 38 patients recurred and 87 died. The HRs for recurrence in patients with elevated AFP, AFP-L3, and DCP defined by BALAD cut-off values were 2.42(1.18-5.00), 1.86(0.98-3.52), and 2.83(1.42-5.61), respectively. For BALAD, the HRs for recurrence and death per unit increased score were 1.48(1.15-1.91) and 1.59(1.28-1.97). For BALAD-2, the HRs for recurrence and death per unit increased class were 1.45(1.06-1.98) and 1.38(1.09-1.76). For recurrence prediction, the combination of three biomarkers had the highest c-statistic of 0.66 vs. 0.64, 0.61, 0.53, and 0.53 for BALAD, BALAD-2, Milan, and UCSF, respectively. Similarly, for death prediction, the combination of three biomarkers had the highest c-statistic of 0.66 vs 0.65,0.61, 0.52, and 0.50 for BALAD, BALAD-2, Milan, and UCSF. A new model combining biomarkers with tumor size at the time of transplant(S-LAD) demonstrated the highest predictive capability with c-statistics of 0.71 and 0.69 for recurrence and death. CONCLUSION BALAD and BALAD-2 are valid in transplant HCC patients, but less predictive than the three biomarkers in combination or the three biomarkers in combination with maximal tumor diameter(S-LAD). | Nicha Wongjarupong Gabriela M Negron-Ocasio Roongruedee Chaiteerakij Benyam D Addissie Essa A Mohamed Kristin C Mara William S Harmsen J Paul Theobald Brian E Peters Joseph G Balsanek Melissa M Ward Nasra H Giama Sudhakar K Venkatesh Denise M Harnois Michael R Charlton Hiroyuki Yamada Alicia Algeciras-Schimnich Melissa R Snyder Terry M Therneau Lewis R Roberts | 2018 | World Journal of Gastroenterology2018,24,12: | 5 |
| 3 | The Ultimate Ownership of Western European Corporation显示文摘 | Faccio Mara Larry H P Lang | 2002 | Journal of Financial Economics2002,65,: | 1 |
| 4 | Topological error eoection of GIS vector data显示文摘 | Maras S S Maras H H Aktug B | 2010 | International Journal of the Physical Sciences2010,5,5: | 1 |
| 5 | Effect of wind direction on the response and capacity surface of a transmission tower 显示文摘 | T G Mara H P Hong | 2013 | Engineering Struc- tures2013,,: | 1 |
| 6 | Application of athree-dimensional network model to the coke formation in FAU,MFI and BEA zeolites 显示文摘 | Ca^mara L D T Cerqueira H S Aranda DAG | 2004 | Catalysis Today2004,,98: | 1 |
| 7 | A prospective, randomized evaluation of intra-abdominal pressures with crystalloid and colloid resuscitation in burn patients显示文摘 | O'Mara MS Slater H Goldfarb IW | 2005 | J Trauma2005,58,5: | 1 |
| 8 | Double versus single renal allografts from agel donors 显示文摘 | Amado A jose mara M Juan Carlos H | 2000 | Transplantation2000,69,10: | 1 |
| 9 | Empirical evaluation of spatial and non-spatial European-scale multimedia fate models:results and implications for chemical risk assessment显示文摘 | ARMITAGE J M COUSINS I T MARA H | 2007 | Journal of Environmental Monitoring2007,9,6: | 1 |
| 10 | Application of PLS and back-propagation neural networks for the estimation of soil properties显示文摘 | ZIAD R PHILIP K H MARA J J | 2005 | Chemometrics and Intelligent Laboratory Systems2005,75,1: | 1 |
| 11 | A prospective, randomized evaluation of intraabdominal pressures with crystalloid and colloid resuscitation in burn patients显示文摘 | O′Mara MS Slater H Goldfarb IW | 2005 | J Trauma2005,58,5: | 1 |
| 12 | Integrin signalling: The tug-of-war in heart hypertrophy显示文摘 | Mara B Emilio H Antonella N | 2006 | Cardiovascular Research2006,70,: | 1 |
| 13 | Methionine concentration in the diet has a tissue-specific effect on chromosomal stability in female mice显示文摘 | Aissa A F Uraula H G T D Mara R | 2013 | Food and Chemical Toxicology2013,62,: | 1 |
| 14 | Aerodynamic measurements of patients with Parkinson's disease显示文摘 | Jiang J O'Mara T Chen H | 1999 | Journal of Voice1999,13,4: | 1 |
| 15 | Defective Rac-mediated proliferation and survival after targeted mutation of the β1 integrin cytodomain显示文摘 | Emilio H Laura B Mara B | 2002 | J Cell Biol2002,157,3: | 1 |
| 16 | Five en-dometrial cancer risk loci identified through genome-wide as-sociation analysis显示文摘 | CHENG T H THOMPSON D J O'MARA T A | 2016 | Nature Genetics2016,48,6: | 1 |
| 17 | Characterization of an amorphous iridium water-oxidation catalyst electrodeposited from organometallic precursors显示文摘 | Blakemore J D Mara M W Kushner-Lenho M N Schley N D Konezny S J Rivalta I Negre C F A Snoeberger R C Kokhan O Huang J Stickrath A Tran L A Parr M L Chen L X Tiede D M Batista V S Crabtree R H Brudvig G W | 2013 | Inorganic Chemistry2013,52,: | 1 |
| 18 | Degradation of Parathion by soil kept moist with and without repeated applications显示文摘 | Mara M De Andrea Kenneth A Lord Richard H | 1982 | Environmental Pollution1982,27,: | 1 |
| 19 | Greenhouse gas mitigation in agriculture显示文摘 | Smith P Martino D Cai Z C Gwary D Janzen H Kumar P McCarl B Ogle S O'Mara F Rice C Scholes B Sirotenko O Howden M McAllister T Pan GX Romanenkov V Schneider U Towprayoon S Wattenbach M Smith J | 2008 | Philosophical Transactions of the Royal SocietyB:Biological Sciences2008,363,: | 1 |
| 20 | Intake of lutein and zeaxanthin differ with age, sex, and ethnicity显示文摘 | Johnson E J Maras J E Rasmussen H M | 2010 | Journal of the American Dietetic Association2010,110,9: | 1 |