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| 1 | Perspectives on new biomarkers in gastric cancer: Diagnostic and prognostic applications显示文摘Gastric cancer is considered one of the most deadly tumors worldwide. Even with the decline in its incidence, the mortality rate of this disease has remained high, mainly due to its late diagnosis and to the lack of precise prognostic markers. The main purpose of this review is to present genetic, epigenetic and proteomic molecular markers that may be used in a diagnostic and prognostic manner and to discuss the pros and cons of each type of marker for improving clinical practice. In this sense, we observed that the use of genetic markers, especially mutations and polymorphisms, should be carefully considered, as they are strongly affected by ethnicity. Proteomic-based markers show promise, but the higher costs of the associated techniques con-tinue to make this approach expensive for routine use. Alternatively, epigenetic markers appear to be very promising, as they can be detected in bodily fluids as well as tissues. However, such markers must be used carefully because epigenetic changes may occur due to environmental factors and aging. Despite the advances in technology and its access, to date, there are few defined biomarkers of prognostic and diagnostic use for gastric tumors. Therefore, the use of a panel of several approaches(genetic, epigenetic and proteomic) should be considered the best alternative for clinical practice. | Danilo do Rosário Pinheiro Wallax Augusto Silva Ferreira Mariceli Baia Leo Barros Mariana Diniz Araújo Symara Rodrigues-Antunes Bárbara do Nascimento Borges | 2014 | World Journal of Gastroenterology2014，20，33： | 4 |
| 2 | Effects of specific inhibition of cyclooxygenase-1 and cyclooxygenase-2 in the rat stomach with normal mucosa and after acid challenge显示文摘 | Gretzer B Maricic N Respondek M | 2001 | British JPharm2001，132，7： | 1 |
| 3 | Register of hazardous materials in printing industry as a tool for sustainable development management 显示文摘 | KIURSKI J MARIC B ADAMOVIC D | 2012 | Renewable Sustainable Energy Rev2012，16，： | 1 |
| 4 | Transgenic sugar beet tolerant to glyphosate 显示文摘 | Maric B K | 1997 | Euphytica1997，，94： | 1 |
| 5 | Effect of SC-560 a selective cyclooxygenase-l inhibitor and its modification by cyclooxygenase-2 inhibition in the rat stomach显示文摘 | Gretzer B Maricic N Schuligoi R | | 0，，： | 1 |
| 6 | Effects of specific inhibition of cyclooxygenase-1 and cyclooxygenase-2 in the rat stomach with mucosa and afier acid ohallenge显示文摘 | Gretzer B Maricic N Respondek M | | 0，，： | 1 |
| 7 | Effects of specific inhibition of cy- clo-oxygenase-1 and cyclo-oxygenase-2 in the rat stomach with nor aM mucosa and after acid challenge 显示文摘 | Gretzer B Maricic N Respondek M | 2001 | Br J Pharmacol2001，132，7： | 1 |
| 8 | Activation of natural killer T cells potentiates or prevents experimental autoimmune encephalomyelitis 显示文摘 | Jahng AW Maricic I Pedersen B | 2001 | J Exp Med2001，194，12： | 1 |
| 9 | 显示文摘 | Gretzer B Ehrlich K Maricic N | 1998 | Br J Pharmacol1998，123，5： | 1 |
| 10 | Styrene/Acrylic Acid Random Copolymers Synthesized by Nitroxide-Mediated Polymerization: Effect of Free Nitroxide on Kinetics and Copolymer Composition显示文摘 | Lessard B Schmidt S C Maric M | 2008 | Macromolecules2008，41，10： | 1 |
| 11 | Activation of Natural Killer T Cells Potentiates or Prevents Experimental Autoimmune Encephalomyelitis 显示文摘 | Maricic L Pedersen B | 2001 | J Expe Med2001，194，： | 1 |
| 12 | Role ofcyclooxygenase-2 in gastric mucosal defense 显示文摘 | Maricic N Gretzera B | 2001 | Life Sci2001，69，2526： | 1 |
| 13 | Solving paraffin deposition problem in tubing by heating cable application显示文摘 | DANILOVIC D S MARICIC V D K COKORILO V B | 2010 | Thermal Science2010，14，1： | 1 |
| 14 | Selective cyelo-oxygenase-2 inhibition and their influence on the protective effect of a mild irrtant in the rat stomach显示文摘 | GRETZER B EHRLICH K MARICIC N | 1998 | Br J Pharmaeol1998，123，： | 1 |
| 15 | Prevalence and etiology of false normal aEEG recordings in neonatal hypoxic-ischaemic encephalopathy显示文摘 | Marics G Cseki A Vá sárhelyi B | | 0，，01： | 1 |
| 16 | Effects of specific inhibition of cyclo-oxygenase-1 and cyclo-oxygenase-2 in the rat stomach with normal mucosa and after acid challenge 显示文摘 | Gretzer B Maricic N Respondek M | 2001 | Br J Pharmacol2001，132，： | 1 |
| 17 | The effects of dietary saturated fat on basal hypothalamic neuroinflammation in rats显示文摘 | Maric T Woodside B Luheshi GN | 2014 | Brain Behav Immun2014，36，： | 1 |
| 18 | Laparescopic mamngement of consecutive ovation pregnancy in a patient with infertility显示文摘 | Terzic M Stimec B Maricic S | 2002 | Zentralbl Gynakol2002，123，3： | 1 |
| 19 | Phosphorylation of p27Kip1 at Thr187 by cyclin-de- pendent kinase 5 modulates neural stem ceil differentiation显示文摘 | Zheng Y L Li B S Rudrabhatla P Shukla V Amin N D Maric D | 2010 | Mol Biol Cell2010，21，： | 1 |
| 20 | A computerized method for the evaluation of root canal morphology显示文摘 | Blaskovic-Subat V Smojver B Maricic B | 1995 | Int Endod J1995，28，6： | 1 |
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