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| 1 | Measurement of the intestinal permeability in chronic kidney disease显示文摘AIM: To evaluate methods measuring the intestinal permeability in chronic kidney disease(CKD) and clarify whether there is an increased intestinal permeability in CKD.METHODS: We reviewed the literature in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-analysis(PRISMA) protocol and performed a systematic literature search through MEDline and EMBASE. All controlled trials and cohort studies using non-invasive methods to assess intestinal permeability in CKD patients were included. Excluded were: Conference abstracts and studies including patients younger than 18 years or animals. From the included studies we summarized the used methods and their advantages and disadvantages. For the comparison of their results we divided the included studies in two categories based on their included patient population, either assessing the intestinal permeability in mild to moderate CKD patients or in end stage renal disease(ESRD) patients. Results were graphically displayed in two plots, one comparing the intestinal permeability in mild to moderate CKD patients to healthy controls and one comparing the intestinal permeability in ESRD patients to healthy controls. RESULTS: From the 480 identified reports, 15 met our inclusion criteria. Methods that were used to assess the intestinal permeability varied from markers measured in plasma to methods based on calculating the urinary excretion of an orally administered test substance. None of the applied methods has been validated in CKD patients and the influence of decreased renal function on the different methods remains unclear to a certain extent. Methods that seem the least likely to be influenced by decreased renal function are the quantitative PCR(qPCR) for bacterial DNA in blood and D-lactate. Considering the results published by the included studies; the studies including patients with mild to moderate CKD conducted conflicting results. Some studies did report an increase in intestinal permeability whilst other did not find a significant increased permeability. However, despite the variety in used methods among the different studies, all studies measuring the intestinal permeability in ESRD point out a significant increased intestinal permeability. Results should nevertheless be interpreted with caution due to the possible influence of a decreased glomerular filtration rate on test results.CONCLUSION: The intestinal permeability in CKD:(1) could be measured by qPCR for bacterial DNA in blood and D-lactate; and(2) seems to be increased in ESRD. | Matty L Terpstra Ramandeep Singh Suzanne E Geerlings Frederike J Bemelman | 2016 | World Journal of Nephrology2016，5，4： | 2 |
| 2 | Is canine fossa access necessary for successful maxillary fungus ball treatment?显示文摘 | Pagella F Matti E Giourgos G | 2009 | Rhinology2009，47，4： | 1 |
| 3 | Paranasal sinus fungus ball: diagnosis and management显示文摘 | Pagella F Matti E De Bernardi F | 2007 | Mycoses2007，50，6： | 1 |
| 4 | Paranasal sinus fungus ball: diagnosis and management 显示文摘 | Pagella F Matti E De Bernardi F | 2007 | Mycoses2007，50，6： | 1 |
| 5 | Rapid alteration of microRNA levels by histone deacetylase inhibition 显示文摘 | Scott G K Mattie M D Berger C E | 2006 | Cancer Res2006，66，3： | 1 |
| 6 | Rapid alteration of microRNA levels by histone deacetylase inhibition显示文摘 | MATTIE M D BERGER C E | 2006 | Cancer Res2006，66，3： | 1 |
| 7 | Cognitive effects after epidural vs general anesthesia in older adults: a randomized trial显示文摘 | Williams Russo P Sharrock N E Mattis S | 1995 | JAMA1995，274，1： | 1 |
| 8 | The impact of inadequate sleep on children's daytime cognitive function 显示文摘 | DAHL R E RYAN N D MATTY M K | 1996 | Semin Pediatr Neurol1996，3，1： | 1 |
| 9 | Determination of the degree of substitution of acetylated starch by hydrolysis, ^1H NMR and TGA/IR 显示文摘 | Matti E Tomas A | 2004 | Carbohydrate Polymers2004，57，： | 1 |
| 10 | EASAT detection of waves, currents and inlet discharge显示文摘 | Mattie M G Lichy D E | 1980 | Int J Remote Sensing1980，1，4： | 1 |
| 11 | Transoral power-assisted marsupialization of vallecular cysts under local anesthesia显示文摘 | PAGELLA F PUSATERI A MATTI E | 2013 | Laryngoscope2013，123，： | 1 |
| 12 | Transoral power-assisted mar- supialization of vaUecular cysts under local anesthesia 显示文摘 | PageUa F Pusateri A Matti E | 2013 | Laryn- goscope2013，123，3： | 1 |
| 13 | How we do it:a combined method of traditional curette and power-assisted endoscopic adenoidectomy显示文摘 | Pagella F Matti E Colombo A | 2009 | Acta Otolaryngol2009，129，5： | 1 |
| 14 | How we do it : a co-mbined method of traditional curette and power-assisted end-oscopic adenoidectomy 显示文摘 | Pagella F Matti E Colombo A | 2009 | Acta Otolaryngol2009，129，5： | 1 |
| 15 | Ordering energy levels of interacting spin systems显示文摘 | LIEB E MATTIS D | 1962 | J Math Phys1962，3，4： | 1 |
| 16 | Development of analytical methods for the determination of sub-ppm concentrations of palladium and iron in methotrexate显示文摘 | Matti N Harri K Keijo E | 2004 | Journal of Pharmaceutical and Biomedical Analysis2004，35，： | 1 |
| 17 | Determination of plasma genistein fatty acid esters following administration of genistein or genistein 4'7-O-dioleate in monkeys显示文摘 | Maija Badeau Matti J Susan E Appt | 2005 | Biochim Biophys Acta2005，1738，： | 1 |
| 18 | How we do it: a combined method of traditional curette and power-assisted endoscopicadenoidectomy 显示文摘 | Pagella F Matti E Colombo A | 2009 | Acta Otolaryngol2009，129，5： | 1 |
| 19 | A putative chemokinereceptor,BLRl,directs B cell migration to defined lymphoid or- gans and specific anatomic compartments of the spleen显示文摘 | Forster R Mattis AE Kremmer E | 1996 | Cell1996，87，： | 1 |
| 20 | A putative chemokine receptor, BLR1, directs B cell migration to defined lymphoid or- gans and specific anatomic compartments of the spleen显示文摘 | F~rster R Mattis AE Kremmer E | 1996 | Cell1996，87，6： | 1 |
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