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| 1 | Crystal Structure of Loliolide (5, 6,7a-Tetrahydro-6-hydroxy-4, 4, 7a-trimethyl-2 (4H)-benzofuranones)显示文摘The structure of the title compound, which was isolated fromClinopodium polycephalum (Vant.) by C. Y. Wu et Hsuan, has been determined byX-ray diffraction analysis. C11H16O3, Mr= 196. The crystal belongs to the monoclinicspace group P21 with a= 6. 072 (3), b=11. 682 (5), c= 7. 865 (4) A, β= 109. 61(4)°, V=525. 5(4) , Z= 2, F(000) =212, Dc= 1.234 g/cm3, μ=0.08 mm-1.The structure was solved by direct methods and refined to R=0. 048 for 616 observedreflections. The molecule is composed of a six-membered ring and a five-membered lactone ring with a methyl and a hydroxy group at the two asymmetrical carbons locatedon the same side of the nucleus. | CHEN Jing-Yu CHEN Jian-Min XIAO Pei-Gen(Institute of Medicinal Plant Development, the Chinese Academy of Medical Sciences,Peking Union Medical College, Beijing 100094)WU Nan LU Yang(Institute of Materia Medica, the Chinese Academy of Medical Sciences,P | 1997 | Chinese Journal of Structural Chemistry1997，16，5： | 2 |
| 2 | Effect of long-distance mad transport on thyroid and adrenal function and haematocrit values in Limousin cattle : influence of body weight decrease 显示文摘 | FAZIO E MEDICA P ALBERGHINA D | 2005 | Veterinary Research Communications2005，29，8： | 1 |
| 3 | Effect of long-dis- tance road transport on thyroid and adrenal function and haematocrlt values in Limousin cattle: influence of body weight decrease 显示文摘 | FAZIO E MEDICA P ALBERGHINA D | 2005 | Veterinary Research Communications2005，29，8： | 1 |
| 4 | Circulating beta-endorphin, adrenocorticotrophic hormone and cortisol levels of stallions before and after short road transport: stress effect of different distances显示文摘 | Fazio E Medica P Aronica V | 2008 | Acta Veterinaria Seandinavica2008，50，1： | 1 |
| 5 | Circulating β-endorphin,adrenocorticotrophic hormone and cortisol levels of stallions before and after short road transport:stress effect of different distances显示文摘 | FAZIO E MEDICA P ARONICA V | | 0，，06： | 1 |
| 6 | Effect of long-distance road transport on thyroid and adrenal function and haematocrit values in Limous in cattle:influence of body weight decrease显示文摘 | Fazio E Medica P Alberghina D et d | 2005 | Vet Res Commun2005，29，： | 1 |
| 7 | Effect of Long-distance Road Transport on Thyroid and Adrenal Function and Haema- tocrit Values in Limousin Cattle: Influence of Body Weight De- crease 显示文摘 | Fazio E Medica P Alberghina D | 2005 | Veterinary Research Communications2005，29，： | 1 |
| 8 | Effect ofLong-distance Road Transport on Thyroid and Adre- nal Function and Haematocrit Values in Limousin Cattle: Influence of Body Weight Decrease显示文摘 | Fazio E Medica P Alberghina D | 2005 | Vet Res Commun2005，29，： | 1 |
| 9 | Effect of Long-distance Road Transport on Thyroid and Adrenal Function and Haematocrit Values in Limousin Cattle:Influence of Body Weight Decrease显示文摘 | Fazio E Medica P Alberghina D | 2005 | Veterinary Research Communications2005，29，： | 1 |
| 10 | The im-pact of off-road vehicle on a desert ecosystem显示文摘 | Vollmer A T Maza B G Medica P A | 1976 | Envi-ronmental Management1976，1，2： | 1 |
| 11 | Two-point Dixon and six-point Dixon magnetic resonance techniques in the detection,quantification and grading of hepatic steatosis显示文摘BACKGROUND Hepatic steatosis is a very common problem worldwide.AIM To assess the performance of two-and six-point Dixon magnetic resonance(MR)techniques in the detection,quantification and grading of hepatic steatosis.METHODS A single-center retrospective study was performed in 62 patients with suspected parenchymal liver disease.MR sequences included two-point Dixon,six-point Dixon,MR spectroscopy(MRS)and MR elastography.Fat fraction(FF)estimates on the Dixon techniques were compared to the MRS-proton density FF(PDFF).Statistical tests used included Pearson’s correlation and receiver operating characteristic.RESULTS FF estimates on the Dixon techniques showed excellent correlation(≥0.95)with MRS-PDFF,and excellent accuracy[area under the receiver operating characteristic(AUROC)≥0.95]in:(1)Detecting steatosis;and(2)Grading severe steatosis,(P<0.001).In iron overload,two-point Dixon was not evaluable due to confounding T2*effects.FF estimates on six-point Dixon vs MRS-PDFF showed a moderate correlation(0.82)in iron overload vs an excellent correlation(0.97)without iron overload,(P<0.03).The accuracy of six-point Dixon in grading mild steatosis improved(AUROC:0.59 to 0.99)when iron overload cases were excluded.The excellent correlation(>0.9)between the Dixon techniques vs MRSPDFF did not change in the presence of liver fibrosis(P<0.01).CONCLUSION Dixon techniques performed satisfactorily for the evaluation of hepatic steatosis but with exceptions. | Mohamed Elfaal Alanna Supersad Craig Ferguson Stephanie Locas Florin Manolea Mitchell P Wilson Medica Sam Wendy Tu Gavin Low | 2023 | World Journal of Radiology2023，15，10： | 0 |
| 12 | Effect of training on resident inter-reader agreement with American College of Radiology Thyroid Imaging Reporting and Data System显示文摘BACKGROUND The American College of Radiology Thyroid Imaging Reporting and Data System(ACR TI-RADS)was introduced to standardize the ultrasound characterization of thyroid nodules.Studies have shown that ACR-TIRADS reduces unnecessary biopsies and improves consistency of imaging recommendations.Despite its widespread adoption,there are few studies to date assessing the inter-reader agreement amongst radiology trainees with limited ultrasound experience.We hypothesize that in PGY-4 radiology residents with no prior exposure to ACR TIRADS,a statistically significant improvement in inter-reader reliability can be achieved with a one hour training session.AIM To evaluate the inter-reader agreement of radiology residents in using ACR TIRADS before and after training.METHODS A single center retrospective cohort study evaluating 50 thyroid nodules in 40 patients of varying TI-RADS levels was performed.Reference standard TI-RADS scores were established through a consensus panel of three fellowship-trained staff radiologists with between 1 and 14 years of clinical experience each.Three PGY-4 radiology residents(trainees)were selected as blinded readers for this study.Each trainee had between 4 to 5 mo of designated ultrasound training.No trainee had received specialized TI-RADS training prior to this study.Each of the readers independently reviewed the 50 testing cases and assigned a TI-RADS score to each case before and after TI-RADS training performed 6 wk apart.Fleiss kappa was used to measure the pooled inter-reader agreement.The relative diagnostic performance of readers,pre-and post-training,when compared against the reference standard.RESULTS There were 33 females and 7 males with a mean age of 56.6±13.6 years.The mean nodule size was 19±14 mm(range from 5 to 63 mm).A statistically significant superior inter-reader agreement was found on the post-training assessment compared to the pre-training assessment for the following variables:1.“Shape”(k of 0.09[slight]pre-training vs 0.67[substantial]post-training,P<0.001),2.“Echogenic foci”(k of 0.28[fair]pre-training vs 0.45[moderate]post-training,P=0.004),3.‘TI-RADS level’(k of 0.14[slight]pre-training vs 0.36[fair]post-training,P<0.001)and 4.‘Recommendations’(k of 0.36[fair]pre-training vs 0.50[moderate]post-training,P=0.02).No significant differences between the preand post-training assessments were found for the variables'composition','echogenicity'and'margins'.There was a general trend towards improved pooled sensitivity with TI-RADS levels 1 to 4 for the post-training assessment while the pooled specificity was relatively high(76.6%-96.8%)for all TI-RADS level.CONCLUSION Statistically significant improvement in inter-reader agreement in the assigning TI-RADS level and recommendations after training is observed.Our study supports the use of dedicated ACR TI-RADS training in radiology residents. | Yang Du Meredith Bara Prayash Katlariwala Roger Croutze Katrin Resch Jonathan Porter Medica Sam Mitchell P Wilson Gavin Low | 2022 | World Journal of Radiology2022，14，1： | 0 |
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