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| 1 | Uptake of HIV Self-testing among Men Who have Sex with Men in Beijing, China: a Cross-sectional Study显示文摘Objective To examine HIV self-testing uptake and its determinates among men who have sex with men(MSM) in Beijing, China. Methods A cross-sectional online survey was conducted in Beijing, China in 2016. Participants were users of a popular Chinese gay networking application and had an unknown or negative HIV status. Univariate and multivariate logistic regression analyses were conducted to examine factors associated with HIV self-testing based on adjusted odds ratio(AOR) and 95% confidence interval(CI). Results Among the 5,996 MSM included in the study, 2,383(39.7%) reported to have used HIV self-testing kits. Willingness to use an HIV self-test kit in the future was expressed by 92% of the participants. High monthly income(AOR = 1.49; CI = 1.10-2.02; P = 0.010), large number of male sex partners(≥ 2: AOR = 1.24; CI = 1.09-1.43; P = 0.002), sexual activity with commercial male sex partners(≥ 2: AOR = 1.94; CI = 1.34-2.82; P = 0.001), long-term drug use(AOR = 1.42; CI = 1.23-1.62; P < 0.001), and long-term HIV voluntary counseling and testing(VCT) attendance(AOR = 3.62; CI = 3.11-4.22; P < 0.001) were all associated with increased odds of HIV self-testing uptake. Conclusion The nearly 40% rate of HIV self-testing uptake among MSM in our sample was high. In addition, an over 90% willingness to use kits in the future was encouraging. HIV self-testing could be an important solution to help China achieve the global target of having 90% of all people living with HIV diagnosed by 2020. | REN Xian Long WU Zun You MI Guo Dong MCGOOGAN Jennifer ROU Ke Ming ZHAO Yan | 2017 | Biomedical and Environmental Sciences2017，30，6： | 13 |
| 2 | A new flavone glycoside from Selaginella moellendorffii Hieron.显示文摘从 Selaginella moellendorffii 神庙的乙醇摘录,新黄酮 O-glycoside 和三已知的黄酮 C-glycosides 作为 5-carboxymethyl-4-hydroxyflavone-7-O--d-glucopyranoside 被孤立并且识别 1, 6,8-di-C--d-glucopyranosylapigenin 2, 6-C--d-glucopyranosyl-8-C--d-xylopyranosyl apigenin 3, 6-C--d-xylopyranosyl-8-C--d-glucopyranosylapigenin 4 分别地。他们的结构被分光镜的方法阐明。 | Tian Mi Zhu Ke Li Chen Wen Bing Zhou | 2008 | Chinese Chemical Letters2008，19，12： | 12 |
| 3 | Immobilization of functional nano-objects in living engineered bacterial biofilms for catalytic applications显示文摘Nanoscale objects feature very large surface-area-to-volume ratios and are now understood as powerful tools for catalysis,but their nature as nanomaterials brings challenges including toxicity and nanomaterial pollution.Immobilization is considered a feasible strategy for addressing these limitations.Here,as a proof-of-concept for the immobilization of nanoscale catalysts in the extracellular matrix of bacterial biofilms,we genetically engineered amyloid monomers of the Escherichia coli curli nanofiber system that are secreted and can self-assemble and anchor nano-objects in a spatially precise manner.We demonstrated three scalable,tunable and reusable catalysis systems:biofilm-anchored gold nanoparticles to reduce nitro aromatic compounds such as the pollutant p-nitrophenol,biofilm-anchored hybrid Cd0.9Zn0.1S quantum dots and gold nanoparticles to degrade organic dyes and biofilm-anchored CdSeS@ZnS quantum dots in a semi-artificial photosynthesis system for hydrogen production.Our work demonstrates how the ability of biofilms to grow in scalable and complex spatial arrangements can be exploited for catalytic applications and clearly illustrates the design utility of segregating high-energy nano-objects from injury-prone cellular components by engineering anchoring points in an extracellular matrix. | Xinyu Wang Jiahua Pu Yi Liu Fang Ba Mengkui Cui Ke Li Yu Xie Yan Nie Qixi Mi Tao Li Lingli Liu Manzhou Zhu Chao Zhong | 2019 | National Science Review2019，6，5： | 9 |
| 4 | A review of high-temperature selective absorbing coatings for solar thermal applications显示文摘Solar selective absorbing coatings directly harvest solar energy in the form of heat.The higher temperatures are required to drive higher power-cycle efficiencies in favor of lower costs of energy.According to different dielectrics,high temperature coatings can mainly be divided to double cermet solar selective coatings,transition metal nitride multilayer coatings and transition metal oxide multilayer coatings.This paper assesses the photothermal conversion efficiency and thermal stability,and discusses the challenges and strategies of improving both thermal and optical properties.Double cermet layers can stabilize nanocrystalline structures by alloying,while transition metal nitride/oxide layers generally choose the reliable materials with superior mechanical properties and thermal stability.The purpose of this review is to get the optimized systems,and propose further research directions at higher temperature,such as all-ceramic absorbing coatings. | Ke Xu Miao Du Lei Hao Jing Mi Qinghe Yu Shijie Li | 2020 | Journal of Materiomics2020，6，1： | 8 |
| 5 | Abundant Production of Reactive Water Radical Cations under Ambient Conditions显示文摘Water radical cations,the crucial intermediates in many aqueous reactions and biochemical processes,are difficult to investigate experimentally due to their short lifetime andlowabundance.Herein,ahomemade device based on energy-tunable discharge was employed to deposit suitable amounts of energy to atmospheric pressure pure water vapor for abundant production of water radical cations,stabilized as(H_(2)O)n^(+·)(n=2-5)with a maximal abundance of≥8.3×10^(6) cps for(H_(2)O)_(2)^(+·),characterized by mass spectrometry(MS).The abundance of water radical cations was optimized by adjusting the experimental parameters such as the discharge voltage(2.5 kV),temperature of the MS inlet(140℃),carrier gas flow(20mL/min),and the distance between the discharge tip and MS inlet(12 mm).The ambient formation of water radical cationswas further confirmedby thehigh reactivity of as-prepared water radical cations,which reacted with benzene,ethyl acetate,and dimethyl disulfide instantly,showing rich chemistry with ionic and radical characteristics.Moreover,the computations usingCCSD(T)//MP2 method and density functional theory confirmed that the O-O single-electron bound dimer(B),as well as the hydronium hydroxyl radical complex(A),accounted for the unusual chemistry of the water radical cations,providing a facile approach to access the high reactivity ofwater radical cations under the ambient conditions. | Meng Wang Xiao-Fei Gao Rui Su Peng He Yuan-Yuan Cheng Ke Li Dongbo Mi Xiaoping Zhang Xinglei Zhang Huanwen Chen R.Graham Cooks | 2022 | CCS Chemistry2022，4，4： | 3 |
| 6 | Indoor massive multiple-input multiple-output channel characterization and performance evaluation显示文摘We present a measurement campaign to characterize an indoor massive multiple-input multiple-output (MIMO) channel system, using a 64-element virtual linear array, a 64-element virtual planar array, and a 128-element virtual planar array. The array topologies are generated using a 3D mechanical turntable. The measurements are conducted at 2, 4, 6, 11, 15, and 22 GHz, with a large bandwidth of 200 MHz. Both line-of-sight (LOS) and non-LOS (NLOS) propagation scenarios are considered. The typical channel parameters are extracted, including path loss,shadow fading, power delay profile, and root mean square (RMS) delay spread. The frequency dependence of these channel parameters is analyzed. The correlation between shadow fading and RMS delay spread is discussed. In addition, the performance of the standard linear precoder—the matched filter, which can be used for intersymbol interference (ISI) mitigation by shortening the RMS delay spread, is investigated. Other performance measures,such as entropy capacity, Demmel condition number, and channel ellipticity, are analyzed. The measured channels,which are in a rich-scattering indoor environment, are found to achieve a performance close to that in independent and identically distributed Rayleigh channels even in an LOS scenario. | Jian-zhi LI Bo AI Rui-si HE Qi WANG Mi YANG Bei ZHANG Ke GUAN Dan-ping HE Zhang-dui ZHONG Ting ZHOU Nan LI | 2017 | Frontiers of Information Technology & Electronic Engineering2017，18，6： | 3 |
| 7 | Amination of electron deficient aryl chlorides promoted by nano sized Mg(OH)_2 under transition metals free condition显示文摘这份报纸论述缺乏的芳基氯化物由 Mg 支持了的电子的胺化作用反应(哦) 2 没有转变金属。仅仅用 stoichiometric, nano 的数量缩放 Mg (哦) 2,对中等孤立的收益好能在 150 在 24 h 以后在 N-methylpyrrolidone (NMP ) | Zhi Hao Cui Zi Hui Meng Yan Qing Mi Peng Wang Qi Wang Lin Man Zhao Ke Jian Cui Fang Yu Zhi Bin Xu | 2012 | Chinese Chemical Letters2012，23，2： | 2 |
| 8 | Next-generation Sequencing Study of Pathogens in Serum from Patients with Febrile Jaundice in Sierra Leone显示文摘Objective People in Western Africa suffer greatly from febrile jaundice, which is caused by a variety of pathogens. However, yellow fever virus(YFV) is the only pathogen under surveillance in Sierra Leone owing to the undeveloped medical and public health system there. Most of the results of YFV identification are negative. Elucidation of the pathogen spectrum is required to reduce the prevalence of febrile jaundice. Methods In the present study, we used Ion Torrent semiconductor sequencing to profile the pathogen spectrum in archived YFV‐negative sera from 96 patients in Sierra Leone who presented with unexplained febrile jaundice. Results The most frequently identified sequencing reads belonged to the following pathogens: cytomegalovirus(89.58%), Epstein‐Barr virus(55.21%), hepatitis C virus(34.38%), rhinovirus(28.13%), hepatitis A virus(20.83%), coxsackievirus(10.42%), Ebola virus(8.33%), hepatitis E virus(8.33%), lyssavirus(4.17%), leptospirosis(4.17%), chikungunya virus(2.08%), Crimean‐Congo hemorrhagic fever virus(1.04%), and hepatitis B virus(1.04%). Conclusion The distribution of sequencing reads suggests a broader spectrum of pathogens for consideration in clinical diagnostics and epidemiological surveillance in Sierra Leone. | ZHANG Yi YE Fei XIA Lian Xu ZHU Ling Wei IDRISSA Laybohr Kamara HUANG Ke Qiang ZHANG Yong LIU Jun BRIMA Kargbo WANG Ji LIANG Mi Fang SONG Jing Dong MA Xue Jun WU Gui Zhen | 2019 | Biomedical and Environmental Sciences2019，32，5： | 2 |
| 9 | Cordyceps militaris polysaccharides can enhance the immunity and antioxidation activity in immunosuppressed mice显示文摘 | Mi Wang Xin Yu Meng Rui Le Yang Tao Qin Xiao Yang Wang Ke Yu Zhang Chen Zhong Fei Ying Li Yuan liang Hu Fei Qun Xue | 2012 | Carbohydrate Polymers2012，，2： | 1 |
| 10 | 202 W dual-end-pumped Tm:YLF laser with a VBG as an output coupler显示文摘We demonstrated a 202 W Tm:YLF slab laser using a reflecting volume Bragg grating(VBG)as an output coupler at room temperature.Two kinds of active heat dissipation methods were used for the VBG to suppress the shift of wavelength caused by its increasing temperature.The maximum continuous wave(CW)output power of 202 W using the microchannel cooling was obtained under the total incident pump power of 553 W,the corresponding slope efficiency and optical-to-optical conversion efficiency were 39.7%and 36.5%,respectively.The central wavelength was 1908.5 nm with the linewidth(full width at half maximum)of 0.57 nm.Meanwhile,with the laser output increasing from 30 to 202 W,the total shift was about 1.0 nm,and the wavelength was limited to two water absorption lines near 1908 nm.The beam quality factors M;were measured to be 2.3 and 4.0 in x and y directions at 202 W. | Disheng Wei Shuyi Mi Ke Yang Junhui Li Jinwen Tang Baoquan Yao Tongyu Dai Xiaoming Duan | 2021 | High Power Laser Science and Engineering2021，9，4： | 1 |
| 11 | Polymerization of Norbornene via an Iron-Based Complex/MAO Catalytic System显示文摘Polynorbornenes were synthesized in the presence of an iron based catalyst, 2,6-bis[1-(2,6-diisopropyl-phenylimino)ethyl]pyridine iron(Ⅱ) dichloride. The FTIR, 1H NMR and 13C NMR analysis results revealed that the structure of the obtained polynorbornenes consisted of vinyl addition polymer substructures without any ring-opening structures. The polymers were amorphous with a short-range order, displayed in the WAXD(wide angle X-ray diffraction) diagrams. The glass transition temperatures ranged from 200 to 400 ℃. The effects of the polymerization reaction conditions, such as Al/Fe molar ratio and toluene/CH2Cl2 volume ratio, on the activity, intrinsic viscosity and Tg were also studied. | MI Xia 1,2, MA Zhi 1,2, YAN Wei-dong 3, LIU Yuan-xia 1,2, WANG Hang 1,2, KE Yu-cai 1 and HU You-liang 1**1. State Key Lab of Engineering Plastics, Center for Molecular Science, Beijing Laboratory of Catalysis, CNPC Key Laboratory of Catalysis,Institute of Chemistry, Chinese Academy of Sciences,Beijing 100080, P. R. China 2. Graduate School of Chinese Academy of Sciences, Beijing 1000803. Institute of Polymer Science and Engineering, Hebei University of Technology,Tianjin 300130, P. R. China | 2002 | Chemical Research in Chinese Universities2002，18，4： | 1 |
| 12 | Using a microdialysis shunt probe to monitor phenolphthalein glucuronide in rats with intact and diverted bile flow显示文摘 | Heppert KE Davies MI | 1999 | Anal Chem Acta1999，379，3： | 1 |
| 13 | Matrix cells from Wharton's jelly From neurons and glia显示文摘 | Mitehell KE Weiss MI Mitehell BM | 2003 | Stem Cells2003，21，1： | 1 |
| 14 | Xylyl derived oxacalixcrowns:Synthesis and crystal structure显示文摘Oxacalixcrowns 1, 2 和 3 经由 dihydroxyoxacalix 的反应被综合[2 ] arene [2 ] pyrazine 5 与 ortho- , meta-bis(bromomethyl)benzenes 和帕拉二度(bromomethyl ) ,在 1:1 的苯塑造。1, 2 和 3 的结构和符合构造被 NMR,集体光谱学和单个水晶 X 光检查衍射分析的联合建立。 | Xiao-Yan Li Chun Hu Ming-Liang Ma Yahu A.Liu Xian-Qiang Mi Biao Jiang Ke Wen | 2013 | Chinese Chemical Letters2013，24，4： | 1 |
| 15 | Diabetic heart muscle disease显示文摘 | Uusitupa MI Mustonen JN Airaksinen KE | 1990 | Ann Meal1990，22，6： | 1 |
| 16 | Intra-host Ebola viral adaption during human infection显示文摘The onsite next generation sequencing(NGS)of Ebola virus(EBOV)genomes during the 2013–2016 Ebola epidemic in Western Africa provides an opportunity to trace the origin,transmission,and evolution of this virus.Herein,we have diagnosed a cohort of EBOV patients in Sierra Leone in 2015,during the late phase of the outbreak.The surviving EBOV patients had a recovery process characterized by decreasing viremia,fever,and biochemical parameters.EBOV genomes sequenced through the longitudinal blood samples of these patients showed dynamic intra-host substitutions of the virus during acute infection,including the previously described short stretches of 13 serial TNC mutations.Remarkably,within individual patients,samples collected during the early phase of infection possessed Ts at these nucleotide sites,whereas they were replaced by Cs in samples collected in the later phase,suggesting that these short stretches of TNC mutations could emerge independently.In addition,up to a total of 35 nucleotide sites spanning the EBOV genome were mutated coincidently.Our study showed the dynamic intra-host adaptation of EBOV during patient recovery and gave more insight into the complex EBOV-host interactions. | William JLiu Weifeng Shi Wuyang Zhu Cong Jin Shumei Zou Ji Wang Yuehua Ke Xiaofeng Li Mi Liu Tao Hu Hang Fan Yigang Tong Xiang Zhao Wenbin Chen Yuhui Zhao Di Liu Gary Wong Chengchao Chen Chunyu Geng Weiwei Xie Hui Jiang Idrissa Laybor Kamara Abdul Kamara Matt Lebby Brima Kargbo Xiangguo Qiu Yu Wang Xiaofeng Liang Mifang Liang Xiaoping Dong Guizhen Wu George F.Gao Yuelong Shu | 2019 | Biosafety and Health2019，1，1： | 1 |
| 17 | A controlled trial of two nucleoside analogues plus indinavir in persons with human immunodeficierlcy virus infection and CD4 cell counts of 200 per cubic millimeter or less显示文摘 | HAMMER SM SQUIRES KE HUGHES MI) | 1997 | N Engl J Med1997，337，11： | 1 |
| 18 | Diabetic heart muscle disease显示文摘 | Uusitupa MI Mustonen JN Airaksinen KE | 1990 | Annals of Medicine1990，22，6： | 1 |
| 19 | XPS and ionic conductivity studies on Li1.3Al0.15Y0.15Ti1.7(PO4)3 ceramics显示文摘 | T. ?alkus E. Kazakevi?ius A. Ke?ionis V. Kazlauskien? J. Mi?kinis A. Dindune Z. Kanepe J. Ronis M. Dudek M. Bu?ko J. R. Dygas W. Bogusz A. F. Orliukas | 2010 | Ionics2010，，7： | 1 |
| 20 | SB216763, a selective small molecule inhibitor of glycogen synthase kinase-3, improves bleomycin-induced pulmonary fibrosis via activating autophagy显示文摘An excessive accumulation of extracellular matrix composed by insoluble collagen is the core pathogenic change of fibroproliferative diseases including pulmonary fibrosis.We recently found that autophagy,a self-catabolic process that maintains intracellular homeostasis,participates critically in the regulation of collagen degradation in the fibrotic tissues.Here we report that treatment of mice with SB216763,a potent and selective inhibitor of glycogen synthase kinase-3(GSK3),significantly decreased the bleomycin(BLM)-induced acute inflammation,attenuated pulmonary fibrosis,improved the lung function and increased animal survival through activating autophagy.Indeed,we found that treatment of mice or cultured cells with SB216763 restored the autophagy in vivo and in vitro through increasing the expression of autophagy related proteins and decreasing the physical interaction of Bcl-2 and Beclin-1.Additionally,SB216763 stimulated the binding of Bcl-2 and GSK3,which reduces the interaction of Bcl2 and Beclin-1.We conclude that the GSK3 inhibitor SB216763 improves the BLM-induced pulmonary fibrosis through stimulating autophagy core complex to restore the activity of autophagy in fibrotic lung tissue.Our work suggests that using a moderate autophagic agonist,such as SB216763,is a promising therapeutic strategy for the treatment of devastating fibroproliferative diseases such as idiopathic pulmonary fibrosis. | Hong Liu Su Mi Zhe Li Xiaoxi Lv Ke Li Fang Hua Zhuowei Hu | 2013 | Acta Pharmaceutica Sinica B2013，3，4： | 1 |
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