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| 1 | Primary colorectal lymphoma:An overview显示文摘Lymphomas represent common hematological malignancies with increasing incidence in recent years.The major site of extranodal non-Hodgkin lymphoma is the gastrointestinal tract.Involvement of the large intestine is rare in comparison to the stomach or small bowel.The disease appears later in life,predominantly in the male population.Complaints are nonspecific,requiring a high index of suspicion in order to establish the diagnosis.The treatment varies from chemotherapy alone to multimodal therapies combining surgery,chemotherapy and radiotherapy.The small number of patients with various histological subtypes and different stage at presentation results in unclear protocol for the treatment of primary colorectal lymphoma.The purpose of this paper is to review current data on primary lymphoma of the colon and rectum while analyzing reported case series and published material on the subject. | Goran Z Stanojevic Milica D Nestorovic Branko R Brankovic Miroslav P Stojanovic Milan M Jovanovic Milan D Radojkovic | 2011 | World Journal of Gastrointestinal Oncology2011,3,1: | 15 |
| 2 | Galectin-3 possible involvement in antipsychotic-induced metabolic changes of schizophrenia:A minireview显示文摘Recently,specific immunometabolic profiles have been postulated in patients with schizophrenia,even before full-blown disease and independent of antipsychotic treatment.Proteomic profiling studies offer a promising potential for elucidating the cellular and molecular pathways that may be involved in the onset and progression of schizophrenia symptoms,and co-occurrent metabolic changes.In view of all this,we were intrigued to explore galectin-3(Gal-3)as a glycan,and in our previous study,we measured its elevated levels in remission of schizophrenia.The finding may be a consequence of antipsychotic treatment and may have an impact on the onset of inflammation,the development of obesity,and the presumed cognitive changes in schizophrenia.In the animal study,it was shown that downregulation of Gal-3 was beneficial in insulin regulation of obesity and cognitive preservation.Strategies involving plasma exchange are discussed in this review,particularly in the context of Gal-3 elimination. | Milica M Borovcanin Katarina Vesic Milena Jovanovic Natasa R Mijailovic | 2021 | World Journal of Diabetes2021,12,10: | 4 |
| 3 | Oxidative β-fragmentation of 19-nor-5α-androstane-3β,5,17β-triol- 3, 17-diacetate显示文摘 | LJUBINKA L LIDIJA B MILICA R | 1983 | Tetrahedron1983,39,21: | 1 |
| 4 | Vascular endothelial growth factor immobilized in collagen scaffold promotes penetration and proliferation of endothelial cells 显示文摘 | Yi HS Molly SS Milica R | 2008 | Acta Biomater2008,4,: | 1 |
| 5 | Neuroimmune,clinical and treatment challenges in multiple sclerosis-related psychoses显示文摘In recent years,epidemiological and genetic studies have shown an association between autoimmune diseases and psychosis.The question arises whether patients with schizophrenia are more likely to develop multiple sclerosis(MS)later in life.It is well known that the immune system plays an important role in the etiopathogenesis of both disorders.Immune disturbances may be similar or very different in terms of different types of immune responses,disturbed myelination,and/or immunogenetic predispositions.A psychotic symptom may be a consequence of the MS diagnosis itself or a separate entity.In this review article,we discussed the timing of onset of psychotic symptoms and MS and whether the use of corticosteroids as therapy for acute relapses in MS is unfairly neglected in patients with psychiatric comorbidities.In addition,we discussed that the anti-inflammatory potential of antipsychotics could be useful and should be considered,especially in the treatment of psychosis that coexists with MS.Autoimmune disorders could precipitate psychotic symptoms,and in this context,autoimmune psychosis must be considered as a persistent symptomatology that requires continuous and specific treatment. | Katarina Vesic Aleksandar Gavrilovic Nataša R Mijailović Milica M Borovcanin | 2023 | World Journal of Psychiatry2023,13,4: | 0 |
| 6 | Diabetes mellitus type 2 as an underlying,comorbid or consequent state of mental disorders显示文摘Somatic disturbances that occur in parallel with psychiatric diseases are a major challenge in clinical practice.Various factors contribute to the development of mental and somatic disorders.Type 2 diabetes mellitus(T2DM)is a significant health burden worldwide,and the prevalence of diabetes in adults is increasing.The comorbidity of diabetes and mental disorders is very common.By sharing a bidirectional link,both T2DM and mental disorders influence each other in various manners,but the exact mechanisms underlying this link are not yet elucidated.The potential mechanisms of both mental disorders and T2DM are related to immune and inflammatory system dysfunction,oxidative stress,endothelial dysfunction,and metabolic disturbances.Moreover,diabetes is also a risk factor for cognitive dysfunction that can range from subtle diabetesassociated cognitive decline to pre-dementia and dementia.A complex relationship between the gut and the brain also represents a new therapeutic approach since gut-brain signalling pathways regulate food intake and hepatic glucose production.The aim of this minireview is to summarize and present the latest data on mutual pathogenic pathways in these disorders,emphasizing their complexity and interweaving.We also focused on the cognitive performances and changes in neurodegenerative disorders.The importance of implementing integrated approaches in treating both of these states is highlighted,along with the need for individual therapeutic strategies. | Milica M Borovcanin Katarina Vesic Ivica Petrovic Ivan P Jovanovic Natasa R Mijailovic | 2023 | World Journal of Diabetes2023,14,5: | 0 |