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| 1 | Predictors of mortality after transjugular portosystemic shunt显示文摘AIM:To investigate if echocardiographic and hemodynamic determinations obtained at the time of transjugular intrahepatic portosystemic shunt(TIPS)can provide prognostic information that will enhance risk stratification of patients.METHODS:We reviewed medical records of 467 patients who underwent TIPS between July 2003 and December 2011 at our institution.We recorded information regarding patient demographics,underlying liver disease,indication for TIPS,baseline laboratory values,hemodynamic determinations at the time of TIPS,and echocardiographic measurements both before and after TIPS.We recorded patient comorbidities that may affect hemodynamic and echocardiographic determinations.We also calculated Model for Endstage Liver Disease(MELD)score and Child Turcotte Pugh(CTP)class.The following pre-and post-TIPS echocardiographic determinations were recorded:Left ventricular ejection fraction,right ventricular(RV)systolic pressure,subjective RV dilation,and subjective RV function.We recorded the following hemodynamic measurements:Right atrial(RA)pressure before and after TIPS,inferior vena cava pressure before and after TIPS,free hepatic vein pressure,portal vein pressure before and after TIPS,and hepatic venous pressure gradient(HVPG).RESULTS:We reviewed 418 patients with portal hypertension undergoing TIPS.RA pressure increased by a mean ± SD of 4.8 ± 3.9 mmH g(P < 0.001),HVPG decreased by 6.8 ± 3.5 mmH g(P < 0.001).In multivariate linear regression analysis,a higher MELD score,lower platelet count,splenectomy and a higher portal vein pressure were independent predictors of higher RA pressure(R = 0.55).Three variables predicted 3-mo mortality after TIPS in a multivariate analysis:Age,MELD score,and CTP grade C.Change in the RA pressure after TIPS predicted long-term mortality(per 1 mm Hg change,HR = 1.03,95%CI:1.01-1.06,P < 0.012).CONCLUSION:RA pressure increased immediately after TIPS particularly in patients with worse liver function,portal hypertension,emergent TIPS placement and history of splenectomy.The increase in RA pressure after TIPS was associated with increased mortality.Age,splenectomy,MELD score and CTP grade were independent predictors of long-term mortality after TIPS. | Mona Ascha Sami Abuqayyas Ibrahim Hanouneh Laith Alkukhun Mark Sands Raed A Dweik Adriano R Tonelli | 2016 | World Journal of Hepatology2016,8,11: | 13 |
| 2 | 表皮通透屏障功能与表皮CD44表达关系的研究显示文摘目的:研究表皮通透屏障功能破坏后表皮CD44的表达。方法:外用胶带破坏裸鼠躯干部表皮通透屏障功能,分别于30min、1h、3h、6h、24h和48h后取皮肤标本,用免疫组化的方法观察CD44在表皮的表达。结果:在表皮通透屏障功能破坏后30min,表皮CD44的表达明显上调;1h和3h后,恢复至正常水平;6h后,表皮CD44的表达又明显增强,并持续到48h;人为地纠正屏障功能(封包)对表皮CD44的表达没有明显影响。结论:表皮通透屏障功能破坏后,表皮CD44的表达增强,其表达的改变与屏障功能本身无显著相关性。 | Mona Man 吕成志 辛淑君 Kenneth R Feingold Peter M Elias 蔄茂强 | 2008 | 临床皮肤科杂志2008,37,7: | 5 |
| 3 | TLR2和TLR4在不同皮炎模型皮肤的表达显示文摘目的研究Toll样受体2(TLR2)和TLR4在不同皮肤炎症的表达是否有区别。方法分别外涂弗博酯、oxazolone或胶带法于裸鼠躯干部制作皮炎模型。用免疫组化的方法观察TLR2和TLR4在真皮和表皮的表达。结果皮炎上调TLR2在表皮的表达及TLR4在真皮的表达;分别外涂弗博酯及oxazolone所诱发的皮炎中炎症细胞浸润较为明显,其TLR2和TLR4的表达增强也较明显;胶带法所诱导的皮炎中其炎症细胞浸润较轻,TLR2和TLR4的表达也较轻。结论皮炎分别上调皮肤TLR2和TLR4在真皮和表皮的表达;TLR2表达增强的程度与炎症程度有关。 | 吕成志 Mona Man 张信江 Kenneth R Feingold Peter M Elias 蔺茂强 | 2009 | 中国皮肤性病学杂志2009,23,7: | 4 |
| 4 | Evaluation of the antifibrotic effectof fenofibrate and rosiglitazone on bleomycin-induced pulmonary fibrosisin rats显示文摘 | Samah M Abd E R Mona K T | 2012 | European Journal of Pharmacology2012,689,13: | 1 |
| 5 | Polyphenols from Cocoa and vascular health-a critical review显示文摘 | Gerald R Mona M Jennifer M | 2009 | International Journal of Molecular Sciences2009,,10: | 1 |
| 6 | Hydrophobins from Aspergillus species cannot be clearly divided into two classes显示文摘 | Britt G Jensen Mikael R Andersen Mona H Pedersen | 2010 | BMC Research Notes2010,3,: | 1 |
| 7 | Early autism detection: are we ready for routine screening? 显示文摘 | MONA A Q JAN W G PETER R | 2011 | Pediatrics2011,128,1: | 1 |
| 8 | A Review of RFO Induction Mo- tor Parameter Estimation Techniques 显示文摘 | Toliyat H A Emil L Mona R | 2003 | IEEE Transactions on Energy Conversion2003,18,2: | 1 |
| 9 | Multiresidue confirmation of β-agonists in bovine retina and liver using LC-ES/ MS/MS 显示文摘 | Lee D Williams Mona I Churchwell Daniel R Doerge | 2004 | Journal of Chromatography B2004,813,: | 1 |
| 10 | Different expression of defense- related genes in arbuscular mycorrhiza显示文摘 | Marcio R Lambais Mona C M | 1995 | Can J Bot1995,73,: | 1 |
| 11 | Molecular basis and clinical application of biological markers of bone turnover显示文摘 | Mona S Calvo C David R | 1996 | Endocrine Reviews1996,17,: | 1 |
| 12 | Comparison of acute myocardial infarct size to two-year mortality in patients <65 to those ≥65 years of age显示文摘 | Todd D Miller Timothy F Christian David O Hodge Mona R Hopfenspirger Bernard J Gersh Raymond J Gibbons | 1999 | The American Journal of Cardiology1999,,: | 1 |
| 13 | Procalcitonin and C-reac- tive protein in hospitalized adult patients with community-acquired pneumonia or exacerbation of asthma or COPD 显示文摘 | Mona B Tristan W C Carlene R | 2011 | Chest2011,139,6: | 1 |
| 14 | tomato DC3000 显示文摘 | BUELL C R JOARDAR V LINDEBERG M et aL The complete genome sequence of the Arabidopsis and tomato pathogen Pseudo- monas syringae pv | 2003 | Proceedings of the Nation- al Academy of Sciences2003,100,10: | 1 |
| 15 | Proinflammatory cytokines in heart failure:double-edged swords显示文摘 | MONA H MOHAMMAD J M NOEL R | 2010 | Heart Fail Rev2010,15,: | 1 |
| 16 | Quantification of soy isoflavones,genistein and daidzein,and conjugates in rat blood using LCIES-MS显示文摘 | Holder C lee Churchwell Mona I Daniel R Doerge | 1999 | Agric Food Chem1999,47,: | 1 |
| 17 | Cytotoxic effects,apoptosis induc-tion and cell cycle alterationsin HT29 cells and T47D cells treated withProdigiosin purified from Serratia marcescens显示文摘 | NOUSHIN R NASRIN S MONA S | 2010 | Journal of Biotechnology2010,150,: | 1 |
| 18 | Diffuse lamellar keratitis:Incidence,associations,outcomes,and a new classification system显示文摘 | Johnson JD Mona HD Pineda R | 2001 | J Cataract Refract Surg2001,27,10: | 1 |
| 19 | Isothiocyanates produced by Brassicaceae species as inhibitors of Fusarium oxysporum 显示文摘 | Smolinska U Mona M J Knudsen G R et aI | 2003 | Plant Dis2003,87,: | 1 |
| 20 | MicroRNA-132 enhances transition from inflammation to proliferation during wound healing显示文摘 | Li Dongqing Wang Aoxue Liu Xi Meisgen Florian Grünler Jacob Botusan Ileana R Narayanan Sampath Erikci Erdem Li Xi Blomqvist Lennart Du Lei Pivarcsi Andor Sonkoly Enik? Chowdhury Kamal Catrina Sergiu-Bogdan St?hle Mona Landén Ning Xu | 2015 | Journal of Clinical Investigation2015,,: | 1 |