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| 1 | Status of antioxidant defense system in chromium-induced Swiss mice tissues显示文摘 | Acharya Monalisa Mishra | 2004 | Environmental Toxicology and Pharmacology2004，17，： | 1 |
| 2 | Diagnostic role of Xpert-MTB RIF assay in osteoarticular tuberculosis:A retrospective study显示文摘BACKGROUND Osteoarticular tuberculosis(OATB) is a severe form of extrapulmonary TB, which causes notable morbidity and warrants a high index of suspicion for prompt management. The diagnosis of OATB poses a challenge, because of the difficulty of collecting the samples and, secondarily, the paucibacillary nature of lesion, which gives poor sensitivity and reproducibility, with long turnaround time of routine/conventional laboratory tests and the requirement for invasive procedures and expertise. The Xpert MTB/RIF assay has been approved by the World Health Organization as a rapid diagnostic tool for diagnosing pulmonary and extrapulmonary TB.AIM To emphasize the diagnostic efficiency of gene Xpert for OATB in suspected patients in a tertiary care hospital of Eastern India.METHODS This retrospective study was conducted in the Department of Microbiology and Orthopaedics by analyzing the data of the gene Xpert assay over a 3-year duration from January 2018 to February 2021. Demographic and clinical data were recorded. The diagnostic efficiency of gene Xpert was evaluated against the composite reference standard(CRS).RESULTS A total of 37 cases fell into positive, probable, and possible categories of osteoarticular TB out of 112 patients included in the study by CRS;gene Xpert result was positive in 35 out of the 37 different CRS categorized cases. Of the 112 cases, culture was put in 40 cases, and, of these cultures, 5 cases showed the growth of MTB. Of these, 4 cases were included in the 35 cases diagnosed by gene Xpert.Smear microscopy was positive in 6 out of 37 CRS categorized cases. When compared with CRS, the sensitivity of gene Xpert assay, culture, and smear was found to be 94.6%, 13.5%, and 16.2%, respectively, while specificity in all the three types of tests was 100%. When kappa statistics were applied, the percentage of agreement gene Xpert, culture, and microscopy with CRS was found to be 95%, 20%, and 22.6%, respectively. Follow-up of the gene Xpert positive patients after getting anti-tubercular treatment revealed improved conditions.CONCLUSION Gene Xpert could detect 31 extra cases with a low and very low mycobacterial load that were missed by the routine culture methods. Hence, more samples should be processed for molecular diagnostic methods like gene Xpert along with other conventional methods for the validation of the molecular test prospectively for the timely diagnosis of osteoarticular TB. | Monalisa Mohanty Baijayantimala Mishra Mantu Jain Lubaib Karaniveed Puthiyapura | 2022 | World Journal of Orthopedics2022，13，3： | 1 |
| 3 | Role of vitamin C on lead acetate induced spermatogenesis in Swiss mice显示文摘 | Usha R Achatya Raja M Rathore Monalisa Mishra | 2003 | Environmental Toxicology and Pharmacology2003，13，： | 1 |
| 4 | Fine structural description of the compound eye of the Madagascar 'hissing cockroach' Gromphadorhinaportentosa (Dictyoptera: Blaberidae)显示文摘马达加斯加的无翼的成年人的复眼“发出嘶嘶声的 cockroach'Gromphadorhina portentosa Sachum, 1853 被光和电子显微镜学检验。每只眼睛包含 2 400-2 500 个主要六角形的方面。然而,影响 ommatidia 的形状和尺寸的不规则是相对普通的,特别向眼睛的边缘。并置眼睛的这种 eucone 类型的一只单个小眼包含八个小网膜房间,它产生一集中地熔化, tiered rhabdom。后者的远侧的结束是塑造漏斗的并且在它的中央提供锥的近似结束。进一步下面, rhabdom (然后由四个小网膜房间的 rhabdomeres 形成了) 假定似方形的侧面,微绒毛在直角在二个方向排列了到对方。通过 rhabdom 的近似区域的生气的节显示三角形的 rhabdom 轮廓和微绒毛(属于与那些不同的 3-4 小网膜房间在似方形的更远侧的 rhabdom 包含了) 在三个方向跑那由 120p 倾向了对方。总的来说,眼睛的组织遵循 orthopteroid 模式并且非常特别地类似于美国蟑螂 Periplaneta 有关美国的文献的。然而,自从 G。portentosa 拥有更少 ommatidia,这能是它的无能的后果飞。在另一方面,方面的大尺寸和多卷的 rhabdoms 建议检测线性地极化的光的飞机的可观的绝对敏感和一个能力。与黄昏的生活方式 G 在联合基于微绒毛取向的模式。portentosa 领先和产地它发生在,预言被成为那这只昆虫在到达森林地板的击倒好光的环境为电子向量辨别使用它的绿受体。 | Monalisa Mishra Victor Benno Meyer-Rochow | 2008 | Insect Science2008，15，2： | 1 |
| 5 | Drosophila melanogaster as an indispensable model to decipher the mode of action of neurotoxic compounds显示文摘Exposure to some toxic compounds causes structural and behavioral anomalies associated with the neurons in the later stage of life.Those toxic compounds are termed as a neurotoxicant,which can be a physical factor,a toxin,an infection,radiation,or maybe a drug.The incongruities caused due to a neurotoxicant further depend on the toxicity of the compound.More importantly,the neurotoxicity of the compound is associated with the concentration and the time point of exposure.The neurodevelopmental defect appears depending on the toxicity of the compound.A neurodevelopmental defect may be associated with a delay in developmental time,defective growth,structural abnormality of many organs,including sensory organs,behavioral abnormalities,or death in the fetus stage.Numerous model organisms are employed to assess the effect of neurotoxicants.The current review summarizes several methods used to check the effect of neurotoxicant and their effect using the model organism Drosophila melanogaster. | MONALISA MISHRA PUNYATOYA PANDA BEDANTA KUMAR BARIK AMRITA MONDAL MRUTUNJAYA PANDA | 2023 | BIOCELL2023，47，1： | 0 |
| 6 | Impact of Hierarchical Architecture of Cryptotermes brevis Wing on the Modulation of Bacterial Adhesion显示文摘The wing architecture is an inspiration to fabricate novel materials with exquisite properties.The current study characterizes the structure and biological function of a termite’s wing.The topography of the surface of the wing was studied by electron microscopy,and surface profilometer.The physicochemical property of the surface was analyzed by Fourier transform infrared spectroscopy,X-ray diffraction spectroscopy,energy-dispersive X-ray spectroscopy,and gas chromatography-mass spectrometry analysis of the epicuticle content.Water Contact Angle measurement confirmed the hydrophobicity of the wing surface.When microorganisms come in contact with the surface of the wing,they adhere to the wing surface due to cell surface properties of their own and the surface chemistry of the wing.The current study reported the adhesion behavior of two bacterial species.The bactericidal activity of the wing was confirmed by counting the bacterial cell viability and examination under a confocal laser scanning microscope.Adhesion of bacteria was observed under the electron microscope.Bacterial oxidative stress,the topography of the wing,and the surface chemistry of the wing are the crucial factors that induce bactericidal activity.The nanostructure along with the chemical composition of the wing can be mimicked for the fabrication of novel material with antibacterial properties. | Sanjeev Kumar Paikra Sumit Mukherjee Nibedita Nayak Janmejaya Bag Monalisa Mishra | 2022 | Journal of Bionic Engineering2022，19，2： | 0 |
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