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| 1 | Role of live microbial feed supplements with reference to anaerobic fungi in ruminant productivity: A review显示文摘To keep the concept of a safe food supply to the consumers, animal feed industries world over are showing an increasing interest in the direct-fed microbials(DFM) for improved animal performance in terms of growth or productivity. This becomes all the more essential in a situation, where a number of the residues of antibiotics and/or other growth stimulants reach in milk and meat with a number of associated potential risks for the consumers. Hence, in the absence of growth stimulants, a positive manipulation of the rumen microbial ecosystem to enhance the feedstuff utilization for improved production efficiency by ruminants has become of much interest to the researchers and entrepreneurs. A few genera of live microbes(i.e., bacteria, fungi and yeasts in different types of formulations from paste to powder) are infrequently used as DFM for the domestic ruminants. These DFM products are live microbial feed supplements containing naturally occurring microbes in the rumen. Among different DFM possibilities, anaerobic rumen fungi(ARF) based additives have been found to improve ruminant productivity consistently during feeding trials. Administration of ARF during the few trials conducted, led to the increased weight gain, milk production, and total tract digestibility of feed components in ruminants. Anaerobic fungi in the rumen display very strong cell-wall degrading cellulolytic and xylanolytic activities through rhizoid development, resulting in the physical disruption of feed structure paving the way for bacterial action. Significant improvements in the fiber digestibility were found to coincide with increases in ARF in the rumen indicating their role. Most of the researches based on DFM have indicated a positive response in nutrient digestion and methane reducing potential during in vivo and/or in vitro supplementation of ARF as DFM. Therefore, DFM especially ARF will gain popularity but it is necessary that all the strains are thoroughly studied for their beneficial properties to have a confirmed ‘generally regarded as safe' status for ruminants. | Anil K Puniya Abdelfattah Z M Salem Sanjay Kumar Sumit S Dagar Gareth W Griffith Monica Puniya Sreenivas R Ravella Nikhil Kumar Tejpal Dhewa Ravinder Kumar | 2015 | Journal of Integrative Agriculture2015，14，3： | 17 |
| 2 | Epigenetic profiles of pre-diabetes transitioning to type 2 diabetes and nephropathy显示文摘AIM: To examine DNA methylation profiles in a longitudinal comparison of pre-diabetes mellitus(Pre-DM) subjects who transitioned to type 2 diabetes mellitus(T2DM).METHODS: We performed DNA methylation study in bisulphite converted DNA from Pre-DM(n = 11) at baseline and at their transition to T2 DM using Illumina Infinium Human Methylation27 Bead Chip, that enables the query of 27578 individual cytosines at Cp G loci throughout the genome, which are focused on the promoter regions of 14495 genes.RESULTS: There were 694 Cp G sites hypomethylated and 174 Cp G sites hypermethylated in progression from Pre-DM to T2 DM, representing putative genes involved in glucose and fructose metabolism, inflammation, oxidative and mitochondrial stress, and fatty acid metabolism. These results suggest that this high throughput platform is able to identify hundreds of prospective Cp G sites associated with diverse genes that may reflect differences in Pre-DM compared with T2 DM. In addition, there were Cp G hypomethylation changes associated with a number of genes that may be associated with development of complications of diabetes, such as nephropathy. These hypomethylation changes were observed in all of the subjects.CONCLUSION: These data suggest that some epigenomic changes that may be involved in the progression of diabetes and/or the development of complications may be apparent at the Pre-DM state or during the transition to diabetes. Hypomethylation of a number of genes related to kidney function may be an early marker for developing diabetic nephropathy. | Thomas A Vander Jagt Monica H Neugebauer Marilee Morgan Donald W Bowden Vallabh O Shah | 2015 | World Journal of Diabetes2015，6，9： | 5 |
| 3 | The Insulin-Like Growth Factors (IGFs) and IGF binding proteins in postnatal development of murine mammary glands显示文摘 | TERESA L W MONICA M R MALINDA A S | 2000 | Journal of Mammary Gland Biology and Neoplasia2000，5，1： | 1 |
| 4 | The Insulin-Like Growth Factors (IGF) and IGF type Ⅰ receptor during postnatal growth of the murine mammary gland: sites of messenger ribonucleic acid expression and potential functions显示文摘 | MONICA M R TERESA L W | 1999 | Endocrinology1999，140，1： | 1 |
| 5 | Evaluating high- fidelity human simulators and standardized patients in an undergraduate nursing health assessment course 显示文摘 | Marian E Barbara W Monica L | 2012 | Nurs Edu Today2012，32，4： | 1 |
| 6 | Staging system for breast cancer: revisions for the 6th edition of the AJCC Cancer Staging Manual显示文摘 | S.Eva Singletary Craig Allred Pandora Ashley Lawrence W Bassett Donald Berry Kirby I Bland Patrick I Borgen Gary M Clark Stephen B Edge Daniel F Hayes Lorie L Hughes Robert V.P Hutter Monica Morrow David L Page Abram Recht Richard L Theriault Ann Thor Don | 2003 | Surgical Clinics of North America2003，，4： | 1 |
| 7 | Comparison of Detec-tion Methods for Heteroresistant Vancomycin-IntermediateStaphylococcus aureus,with the Population Analysis ProfileMethod as the Reference Method显示文摘 | Sarah W Monica M Karen F | 2011 | J Clin Microbiol2011，49，1： | 1 |
| 8 | Melanoma - restricted genes 显示文摘 | Ena W Monica C Panelli | 2004 | J Transl Med2004，2，： | 1 |
| 9 | Molecular systematics of the order anaspidea based on mitochondrial DNA sequence(12S,16S,and COⅠ)显示文摘 | Monica M Patrick J W | 2000 | Molecular Phylogenetics and Evolution2000，15，1： | 1 |
| 10 | Discre- tionary and Transactional Human Resource Practices and Employee Outcomes ,The Role of Perceived Or- ganizational Support显示文摘 | MONICA C G SANDY J W BERRIN E | 2012 | Human Resource Manage- ment2012，51，5： | 1 |
| 11 | Quantifying Self-Report Measures’ Overestimation of Mobility Scores Postarthroplasty/Invited Commentary/Invited Commentary/Author Response显示文摘 | Stratford Paul W Kennedy Deborah M Maly Monica R MacIntyre Norma J Mizner Ryan L Pua Yong Hao Bennell Kim L | 2010 | Physical Therapy2010，，9： | 1 |
| 12 | Inhi- bition of rat mammary tumorigenesis by concord grape juice constitu- ents显示文摘 | Singletary Keith W Stansbury Matthew J Giusti Monica | 2003 | Journal of Agricultural and Food Chemistry2003，51，25： | 1 |
| 13 | Angiotensin-I converting enzyme inhibitory activity of hydrolysates from oat(Avena sativa) proteins by in silico and in vitro analyses显示文摘 | CHEUNG I W NAKAYAMA S MONICA N K | 2009 | Journal of Agricultural and Food Chemistry2009，57，19： | 1 |
| 14 | P ressurised fluid extraction (PFE) as an alternative general method for the determination of pesticide residues in rape seed显示文摘 | TUIJA P GIORGIS I MONICA W | 2002 | The Analyst2002，127，： | 1 |
| 15 | Associations between the SS variant of 5-HT- TLPR and PTSD among adults with histories of childhood emotional a- buse : Results from two African American independent samples 显示文摘 | KATE W MONICA U | 2014 | J Affec Disord2014，61，1： | 1 |
| 16 | The dual role of IL-10显示文摘 | Simon M Monica CP Ena W | 2003 | Trends in Immunol2003，24，1： | 1 |
| 17 | Trophic relations in a streamfood web:importance of fatty acids for macroinvertebrate consum-ers显示文摘 | MONICA T R JOHN D W ALISSA A P | 2007 | Journal of the American Benthological Society2007，26，3： | 1 |
| 18 | The creative process: the effects of group memory on individual idea generation显示文摘 | Satzinger John W Carfield Monica J Nagasundaram Murli | 1999 | Journal of Management Information Systems1999，15，4： | 1 |
| 19 | Impact of the pulmonary arterycatheter in critically ill patients:meta-analysis of randomized clinicaltrials显示文摘 | Monica R Vic H Lynne W | 2005 | JAMA2005，294，13： | 1 |
| 20 | Nonclinical Dose Formulation Analysis Method Validation and Sample Analysis 显示文摘 | MONICA L W PETER B TERESA R H | 2010 | AAPS J2010，12，4： | 1 |
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