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| 1 | Exploring Seasonal and Circadian Rhythms in Structural Traits of Field Maize from LiDAR Time Series显示文摘Plant growth rhythm in structural traits is important for better understanding plant response to the ever-changing environment.Terrestrial laser scanning(TLS)is a well-suited tool to study structural rhythm under field conditions.Recent studies have used TLS to describe the structural rhythm of trees,but no consistent patterns have been drawn.Meanwhile,whether TLS can capture structural rhythm in crops is unclear.Here,we aim to explore the seasonal and circadian rhythms in maize structural traits at both the plant and leaf levels from time-series TLS.The seasonal rhythm was studied using TLS data collected at four key growth periods,including jointing,bell-mouthed,heading,and maturity periods.Circadian rhythms were explored by using TLS data acquired around every 2 hours in a whole day under standard and cold stress conditions.Results showed that TLS can quantify the seasonal and circadian rhythm in structural traits at both plant and leaf levels.(1)Leaf inclination angle decreased significantly between the jointing stage and bell-mouthed stage.Leaf azimuth was stable after the jointing stage.(2)Some individual-level structural rhythms(e.g.,azimuth and projected leaf area/PLA)were consistent with leaf-level structural rhythms.(3)The circadian rhythms of some traits(e.g.,PLA)were not consistent under standard and cold stress conditions.(4)Environmental factors showed better correlations with leaf traits under cold stress than standard conditions.Temperature was the most important factor that significantly correlated with all leaf traits except leaf azimuth.This study highlights the potential of time-series TLS in studying outdoor agricultural chronobiology. | Shichao Jin Yanjun Su Yongguang Zhang Shilin Song Qing Li Zhonghua Liu Qin Ma Yan Ge LingLi Liu Yanfeng Ding Frédéric Baret Qinghua Guo | 2021 | Plant Phenomics2021，3，1： | 5 |
| 2 | Innate and adaptive immune responses toward nanomedicines显示文摘Since the commercialization of the frst liposomes used for drug delivery,Doxil/Caelyx® and Myocet®,tremendous progress has been made in understanding interactions between nanomedicines and biological systems.Fundamental work at the interface of engineering and medicine has allowed nanomedicines to deliver therapeutic small molecules and nucleic acids more effciently.While nanomedicines are used in oncology for immunotherapy or to deliver combinations of cytotoxics,the clinical successes of gene silencing approaches like patisiran lipid complexes(Onpattro®)have paved the way for a variety of therapies beyond cancer.In parallel,the global severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)pandemic has highlighted the potential of mR NA vaccines to develop immunization strategies at unprecedented speed.To rationally design therapeutic and vaccines,chemists,materials scientists,and drug delivery experts need to better understand how nanotechnologies interact with the immune system.This review presents a comprehensive overview of the innate and adaptative immune systems and emphasizes the intricate mechanisms through which nanomedicines interact with these biological functions. | Iara Maíra de Oliveira Viana Sabrina Roussel Joan Defrêne Eliana Martins Lima Frédéric Barabé Nicolas Bertrand | 2021 | Acta Pharmaceutica Sinica B2021，11，4： | 5 |
| 3 | Esterases of Varroa destructor (Acari: Varroidae), parasitic mite of the honeybee显示文摘 | Ma?gorzata Dmitryjuk Krystyna ?ó?towska Regina Fr?czek Zbigniew Lipiński | 2014 | Experimental and Applied Acarology2014，，： | 2 |
| 4 | Ultrasonographic diagnosis of hepatic fibrosis or cirrhosis显示文摘 | Christophe Aubé Frédéric Oberti Nouri Korali Marc-Antoine Namour Didier Loisel Jean-Yves Tanguy Emmanuelle Valsesia Christophe Pilette Marie Christine Rousselet Pierre Bedossa Hervé Rifflet Moussa Y Ma?ga Dominique Penneau-Fontbonne Christine Caron Paul C | 1999 | Journal of Hepatology1999，，3： | 2 |
| 5 | Shear wave elastography of tumour growth in a human breast Cancer model with pathologieal correlation显示文摘 | Chamming's F Latorre-Ossa H Le Fr~re-Belda MA | 2013 | Eur Radiol2013，23，8： | 1 |
| 6 | What is the signifi- cance of endoleaks and endotension显示文摘 | Heikkinen MA Arko FR Zarins CK | 2004 | Surg Clin North Am2004，84，5： | 1 |
| 7 | Diagnosis and management of acute myeloid leukemia in adults:recommendations from an international expert panel,on behalf of the European LeukemiaNet显示文摘 | Dhner H Estey EH Amadori S Appelbaum FR Büchner T Burnett AK Dombret H Fenaux P Grimwade D Larson RA Lo-Coco F Naoe T Niederwieser D Ossenkoppele GJ Sanz MA Sierra J Tallman MS Lwenberg B Bloomfield CD | 2010 | {H}Blood2010，，03： | 1 |
| 8 | Effect of Curcuma ze- doaria crude extract against tumor progression and immunomodulation 显示文摘 | Carvalho FR Vassao RC Nicoletti MA | 2010 | J Venom Anita Toxins incl Trop Dis2010，16，2： | 1 |
| 9 | Mechanism of vascular smooth muscle cells activation by hydrogen peroxide: role of phospholipase C gamma 显示文摘 | Gonzalez Pacheco FR Caramelo C Castilla MA | 2002 | Nephrol Dial Transplant2002，17，3： | 1 |
| 10 | Blockade of pro grammed death-1 ligands on dendritic ceils enhances T cell ac tivation and cytokine production 显示文摘 | Brown JA Dorfman DM Ma FR | 2003 | Immunology2003，170，： | 1 |
| 11 | Sexual function after partial penectomy for penile cancer 显示文摘 | Romero FR Romero KR Mattos MA | 2005 | Urology2005，66，6： | 1 |
| 12 | Blockade of programmed death 1 ligands on dendritic cells enhanced T cell activation and cyto kine oroduction 显示文摘 | Brown JA Dorfman DM Ma FR | 2005 | J Immunol2005，170，3： | 1 |
| 13 | Maternal second trimester serum tumor necrosis factor-alpha-soluble receptor p55 (sTNF55) and subsquent risk of preeclampsia显示文摘 | WILLIUMS MA FARRAND A MITTENDOR FR | 1999 | Am J Epidemiol1999，149，4： | 1 |
| 14 | Blockade of programmed death-1 ligands on dendritic cells enhances T cell activation and cytokine production显示文摘 | Brown JA Dorfman DM Ma FR | 2003 | J Immunol2003，170，3： | 1 |
| 15 | Blocked of programmed death-1 ligands on dendritic cells,enhances T cell activation and CKs produces显示文摘 | Dorfman DM Ma FR | 2003 | J Immunol2003，170，： | 1 |
| 16 | Anti-TNF-alphatherapies : the next generation 显示文摘 | Palladino MA Bahjat FR Theodorakis EA | 2003 | Nat Rev Drug Discov2003，2，9： | 1 |
| 17 | Blockade of programmed death-1 ligands on dendritic cells enhances T cell activation and cytokine production 显示文摘 | Brown JA Dorfman DM Ma FR | 2003 | J Immunol2003，170，3： | 1 |
| 18 | Blockade of programmed death-1 ligands on dendritic cells enhances T cell activation and cytokine production显示文摘 | Brown JA Dorfman DM Ma FR | 2003 | J Immunol2003，170，3： | 1 |
| 19 | Blockade of programmed death-1 ligands on dendritic cells enhances T cell activation and cytokine production显示文摘 | Brown JA Dorfman DM Ma FR | 2003 | J Immunol2003，170，3： | 1 |
| 20 | Blockade of programmed death-1 ligands on dendritic cells enhances T cell activation and cytokine production 显示文摘 | Brown JA Dorfman DM Ma FR | 2003 | J Immunol2003，170，3： | 1 |
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