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| 1 | Prions and their lethal journey to the brain显示文摘 | Mabbott N A Macpherson G | 2006 | Nature Rev Microbiol2006，4，11： | 1 |
| 2 | Migrating intestinal dendritic cells transport PrPSc from the gut显示文摘 | FARQUHAR C F MABBOTT N A | 2002 | J Gen Virol2002，83，1： | 1 |
| 3 | Temporary inactivation of follicular dendritic cells delays neuroinvasion of scrapie显示文摘 | Mabbott N A Mackay F Minnsi F | 2000 | Nature Medicine2000，7，： | 1 |
| 4 | Follicular dendritic cell dedifferentiation reduces scrapie susceptibility following inoculation via the skin显示文摘 | Mohan J Bruce M E Mabbott N A | 2005 | Immunology2005，114，2： | 1 |
| 5 | Prions and their lethal journey to the brain显示文摘 | Mabbott N A MacPherson G G | 2006 | Nat Rev Microbiol2006，4，3： | 1 |
| 6 | Prions and their lethal journey to thc brain显示文摘 | MABBOTT N A MACPHERSON G | 2006 | Nature Rev Microbiol2006，4，11： | 1 |
| 7 | Migrating intestinal dendritic cells transport PrP ( Sc ) from the gut 显示文摘 | Huang F P Farquhar C F Mabbott N A | 2002 | J Gen Virol2002，83，1： | 1 |
| 8 | Designing learner-controlled educational interaction based on learning/cognitive style and learner behaviour 显示文摘 | Papanikolaou K A Mabbott A Bull S | 2006 | Interacting with Computers2006，18，3： | 1 |
| 9 | Follicular dendritic cell dedifferentiation by treatment with an inhibitor of the lymphotoxin pathway dramatically reduces scrapie susceptibility显示文摘 | Mabbott N A Young J McConnell I | 2003 | J Virol2003，77，： | 1 |
| 10 | Follicular dendriticay dramatically reduces scrapie susceptibility显示文摘 | MABBOTT N A YOUNG J MC CONNELL I | 2003 | J Virol2003，77，8： | 1 |
| 11 | Prions and their lethal journey to the brain 显示文摘 | Mabbott N A Macpherson G G | 2006 | Nat Rev Microbiol2006，4，3： | 1 |
| 12 | Follicular dendritic cell dedifferentiation by treatment with an inhibitor of the lymphotoxin pathway dramatically reduces scrapie susceptibility显示文摘 | Mabbott N A Young J McConnell I | 2003 | J Virol2003，77，12： | 1 |
| 13 | Chemical microscopy applied to biolozical systems 显示文摘 | Navratil M Mabbott G A Arriaga E A | 2006 | Analytical Chemistry2006，78，： | 1 |
| 14 | Temporary inactivation of follicular dendritic cells delays neuroinvasion of scrapie 显示文摘 | Mabbott N A Mackay F Miuns F | 2000 | Nat Med2000，6，7： | 1 |
| 15 | Prions and their lethal journey to the brain显示文摘 | MABBOTT N A MACPHERSON G G | 2006 | Nat Rev Microbiol2006，4，3： | 1 |
| 16 | Tumor necrosis factor alpha-deficient,but not interleukin-6-deficient,mice resist peripheral infection with scrapie显示文摘 | Mabbott NA Williams A Farquhar CF | 2000 | J Virol2000，74，7： | 1 |
| 17 | Prions and their lethal journey to the brain显示文摘 | Mabbott N A MacPherson G G | 2006 | Nat Rev Microbiol2006，4，3： | 1 |
| 18 | Aging and the mucosal immune system in the intestine显示文摘 | MABBOTT N A KOBAYASHI A SEHGAL A | 2015 | Biogerontology2015，16，2： | 1 |
| 19 | Follicular dendritic cells in TSE pathogenesis显示文摘 | Bruce M E Brown K L Mabbott N A | 2000 | Immunology Today2000，21，： | 1 |
| 20 | 小胶质细胞缺乏加速朊病毒病但不增强朊病毒在大脑中的积累显示文摘朊病毒病是与朊病毒蛋白错误折叠相关的传染性神经退行性疾病。先前的研究表明,减少小胶质细胞会加速中枢神经系统(CNS)朊病毒病并增加朊病毒在大脑中的积累,这表明小胶质细胞通过吞噬和破坏朊病毒以提供神经保护作用。在Csf1rΔFIRE小鼠中,删除Csf1r中的增强子会特异性地阻止小胶质细胞的发育。然而该小鼠大脑发育正常,并且未显示出如其他小胶质细胞缺陷模型中报道的缺陷。用Csf1rΔFIRE小鼠作为研究小胶质细胞缺乏对中枢神经系统朊病病的影响的改良模型。尽管Csf1rΔFIRE小鼠比野生型小鼠更早地死于CNS朊病毒病,但它们大脑中朊病毒的积累却减少了。而星形胶质细胞则表现出更早的非极化反应性激活,增强了对神经元内容物的吞噬作用和非折叠蛋白质反应。我们的数据表明,小胶质细胞在中枢神经系统朊病毒病中的作用并非简单地吞噬和破坏朊病毒,而是提供宿主保护并限制反应性星形胶质细胞的有害活动。 | Barry M Bradford Lynne I McGuire David A Hume Clare Pridans Neil A Mabbott 杜一星(编译) | 2022 | 神经损伤与功能重建2022，17，9： | 0 |
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