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| 1 | 烟酰胺磷酸核糖基转移酶促进肺血管重塑,是肺动脉高压的治疗靶点显示文摘肺动脉高压(pulmonary arterial hypertension,PAH)是一种严重的进行性疾病,其标志之一是肺血管重塑。烟酰胺磷酸核糖基转移酶(nicotinamide phosphoribosyl transferase,NAMPT)是调节细胞内烟酰胺腺嘌呤二核苷酸水平、细胞氧化还原状态,调节组蛋白脱乙酰酶,促进细胞增殖和抑制凋亡的一种细胞酶。研究人员假设NAMPT可促进肺血管重塑, | Chen J Sysol JR Singla S Zhao S Yamamura A Valdez-Jasso D Abbasi T Shioura KM Sahni S Reddy V Sridhar A Gao H Torres J Camp SM Tang H Ye SQ Comhair S Dweik R Hassoun P Yuan JX Garcia JG Machado RF 刘莉 叶鹏 | 2017 | 中华高血压杂志2017，25，2： | 10 |
| 2 | 螺内酯与可乐定作为难治性高血压第4种治疗药物的比较:难治性高血压的最佳治疗随机研究显示文摘该研究旨在通过一个多中心随机试验对作为难治性高血压患者的第4种治疗药物的螺内酯与可乐定进行比较。采用药丸计数评估药物治疗依从性。难治性高血压患者(定义为包括1种利尿剂在内的3种药物治疗12周,诊室及动态血压监测血压仍未控制)随机给予螺内酯(12.5~50 mg/d)或可乐定(0.1~0.3mg,2次/d)继续治疗12周。 | Krieger EM Drager LF Giorgi DMA Pereira AC Barreto-Filho JAS Nogueira AR Mill JG Lotufo PA Amodeo C Batista MC Bodanese LC Carvalho ACC Castro I Chaves H Costa EAS Feitosa GS Franco RJS Fuchs FD Guimarāes AC Jardim PC Machado CA Magalhāes ME Mion D Jr Nascimento RM Nobre F Nóbrega AC Ribeiro ALP Rodrigues-Sobrinho CR Sanjuliani AF Teixeira MDCB Krieger JE ReHOT Investigators 赵狄 练桂丽 | 2018 | 中华高血压杂志2018，26，3： | 7 |
| 3 | Immunotherapy for de novo renal transplantation :what's in the pipeline? 显示文摘 | TEDESCO SILVA H JR PINHEIRO MACHADO P ROSSO FELIPE C | 2006 | Drugs2006，66，13： | 1 |
| 4 | Probing the mechanism of the Heck reaction with arene diazonium salts by electrospray mass and tandem mass spectrometry 显示文摘 | SABINO A A MACHADO A H L ROQUE C D | 2004 | Angew Chem Int Ed2004，43，19： | 1 |
| 5 | Osmotic response in Lactobacillus casei ATCC 393:biochemical and biophysical characteristics of membrane显示文摘 | Machado M C Lopez C S Heras H | 2004 | Arch Biochem Biophy2004，422，： | 1 |
| 6 | New oxidation catalysts based on iron(III) porphyrins immobilized on Mg-Al layered double hydroxides modified with triethanolamine 显示文摘 | CASTRO K A D F BAIL A GROSZEWICZ P B MACHADO G S SCHREINER W H WYPYCH F NAKAGAKI S | 2010 | Appl Catal A: Gen2010，386，： | 1 |
| 7 | Ten - year experience using antegrade enemas in children显示文摘 | Mugie S M Machado R S Mousa H M | 2012 | J Pediatr2012，161，4： | 1 |
| 8 | Recovery of soianesol from tobacco as a value- added byproduct for alternative applications显示文摘 | MACHADO P A FU H KRATOCHVIL R J | 2010 | Bioresource technology2010，101，3： | 1 |
| 9 | ApoB genehaplo type is associated with lipid profile of higher risk forcoronary heart disease in Caucasian Brazilian men 显示文摘 | Machado M O H irata M H Bertolami M C | 2001 | J Clin LabAnal2001，15，1： | 1 |
| 10 | Extraction of lemongrass essential oil with dense carbon dioxide显示文摘 | Carlson L H C Machado R A F Spricigo C B | 2001 | J Supercrit Fluids2001，21，： | 1 |
| 11 | Non-alcoholic fatty liver disease and insulin resistance显示文摘 | Machado M Cortez-pinto H | 2005 | Eur J Gastroenterol Hepatol2005，17，8： | 1 |
| 12 | The determinant step in ergot alkaloid biosynthesis by an endophyte of perennial ryegrass 显示文摘 | Wang J H Machado C Panaccione D G | 2004 | Fungal Genet Biol2004，41，： | 1 |
| 13 | Neonatal screening of hemoglobinopathies in a population residing in Portugal显示文摘 | Peres M J Carreiro M H Machado M C | 1996 | Acta Med Port1996，9，46： | 1 |
| 14 | When your child with epilepsy die suddenly : febrile seizures are part of the process 显示文摘 | TERRA V C MACHADO H R SAKAMOTO A C | 2011 | Arq Neuropsiquiatr2011，69，2： | 1 |
| 15 | A canine model of laparoscopic segmental liver resection显示文摘 | Machado M A Galvgo F H Pompeu E | 2004 | Laparoen- dosc Adv Surg Tech A2004，14，5： | 1 |
| 16 | Effects of starvation, refeeding and insulin on energy-linked metabolic process in catfish(Rhamdia hilarii) adapted to a carbohydrate-rich diet 显示文摘 | Machado C R Garotalo M A R Migtiorini R H | 1988 | Gen Comp Endocrinol1988，71，3： | 1 |
| 17 | Effects of starvation refeeding and insulin on energy linked metabolic process in catfish Rhamdio hilarii adapted to a carbohydrate rich diet显示文摘 | Machado C R Garofalo M A R Miglioroni R H | 1988 | General and Comparative Endocrinology1988，71，3： | 1 |
| 18 | Regeneration of transgenic plants of Prunus armeniaca containing the coat protein gene of Plum Pox Virus显示文摘 | da CAMARA MACHADO M L da CAMARA MACHADO A HANZER V WEISS H REGNER F STEINKELINER H | 1992 | Plant Cell Rep1992，11，： | 1 |
| 19 | Photocatalytic degradation of lignin and lignin models,using titanium dioxide:the role of the hydroxyl radical显示文摘 | Machado A E H Falone S Z Ruggiero R | 2000 | Chemosphere2000，40，1： | 1 |
| 20 | Hepatic histology in obese patients undergoing bariatric surgery显示文摘 | Machado M Marques-Vidal P Cortez-Pinto H | 2006 | J Hepatol2006，45，4： | 1 |
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