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| 1 | Magnetic resonance imaging in assessment of stress urinary incontinence in women: Parameters differentiating urethral hypermobility and intrinsic sphincter deficiency显示文摘AIM: To define the magnetic resonance imaging(MRI) parameters differentiating urethral hypermobility(UH) and intrinsic sphincter deficiency(ISD) in women with stress urinary incontinence(SUI).METHODS: The static and dynamic MR images of 21 patients with SUI were correlated to urodynamic(UD) findings and compared to those of 10 continent controls. For the assessment of the urethra and integrity of the urethral support structures, we applied the highresolution endocavitary MRI, such as intraurethral MRI, endovaginal or endorectal MRI. For the functional imaging of the urethral support, we performed dynamic MRI with the pelvic phased array coil. We assessed the following MRI parameters in both the patient and thevolunteer groups:(1) urethral angle;(2) bladder neck descent;(3) status of the periurethral ligaments,(4) vaginal shape;(5) urethral sphincter integrity, length and muscle thickness at mid urethra;(6) bladder neck funneling;(7) status of the puborectalis muscle;(8) pubo-vaginal distance. UDs parameters were assessed in the patient study group as follows:(1) urethral mobility angle on Q-tip test;(2) Valsalva leak point pressure(VLPP) measured at 250 cc bladder volume; and(3) maximum urethral closure pressure(MUCP). The UH type of SUI was defined with the Q-tip test angle over 30 degrees, and VLPP pressure over 60 cm H2 O. The ISD incontinence was defined with MUCP pressure below 20 cm H2 O, and VLPP pressure less or equal to 60 cm H2 O. We considered the associations between the MRI and clinical data and UDs using a variety of statistical tools to include linear regression, multivariate logistic regression and receiver operating characteristic(ROC) analysis. All statistical analyses were performed using STATA version 9.0(Stata Corp LP, College Station, TX).RESULTS: In the incontinent group, 52% have history of vaginal delivery trauma as compared to none in control group(P < 0.001). There was no difference between the continent volunteers and incontinent patients in body habitus as assessed by the body mass index. Pubovaginal distance and periurethral ligament disruption are significantly associated with incontinence; periurethral ligament symmetricity reduces the odds of incontinence by 87%. Bladder neck funneling and length of the suprapubic urethral sphincter are significantly associated with the type of incontinence on UDs; funneling reduced the odds of pure UH by almost 95%; increasing suprapubic urethral sphincter length at rest is highly associated with UH. Both MRI variables result in a predictive model for UDs diagnosis(area under the ROC = 0.944). CONCLUSION: MRI may play an important role in assessing the contribution of hypermobility and sphincteric dysfunction to the SUI in women when considering treatment options. | Katarzyna Jadwiga Macura Richard Eugene Thompson David Alan Bluemke Rene Genadry | 2015 | World Journal of Radiology2015,7,11: | 10 |
| 2 | Female urinary incontinence: pathophysiology, methods of evaluation and role of MR imaging显示文摘 | Katarzyna J. Macura Rene R. Genadry | 2008 | Abdominal Imaging2008,,3: | 1 |
| 3 | Patterns of enhancementon breast MR images :interpretation and imag- ing pitfalls 显示文摘 | Macura KJ Ouwerkerk R Jacobs MA | 2006 | Radiographics2006,26,6: | 1 |
| 4 | Pathogenesis in acute aortic syndromes:aortic dissection,intramural hematoma,and penetrating atherosclerotic aortic ulcer显示文摘 | Macura KJ corl FM Fishman EK | 2003 | A JR2003,181,2: | 1 |
| 5 | A 'structural' water molecule in the family of fatty acid binding protein显示文摘 | Likic V A Uranic N Macura S | 2009 | Prot Sci2009,9,: | 1 |
| 6 | Magnetic resonance imaging of pelvic floor defects in women显示文摘 | Macura KJ | | 0,,: | 1 |
| 7 | Pathogenesis in acute aortic syndromes: aortic aneurysm leak and rupture and traumatic aortic transection 显示文摘 | MACURA J K CORL F M FISHMAN E K | 2003 | Am J Roentgenol2003,181,: | 1 |
| 8 | Relationship of temporal resolution to diagnostic performance for dynamic contrast enhanced MRI of the breast显示文摘 | El Khouli RH Macura KJ Barker PB | 2009 | J Magn Reson Imaging2009,0,5: | 1 |
| 9 | MR imaging of the female urethra and supporting ligaments in assessment of urinary inconti- nence : spectrum of abnormalities 显示文摘 | Macura K J Genadry RR Bluemke DA | 2006 | RadioGraphics2006,26,4: | 1 |
| 10 | Evaluation of solitary pulmonary nodule detected during computed tomography examination显示文摘 | Horomanska A Macura KJ | 2012 | Pol J Radiol2012,77,2: | 1 |
| 11 | MRI of peri- anal fistulas: bridging the radiological-surgical divide 显示文摘 | Gage KL Deshmukh S Macura K J | 2013 | Abdom Imaging2013,38,5: | 1 |
| 12 | Antitumor effects of TRAIL-expressing mesenchymal stromal cells in a mouse xenograft model of human mesothelioma显示文摘 | Lathrop MJ Sage EK Macura SL | 2015 | Cancer Gene Ther2015,22,1: | 1 |
| 13 | Role of computed tomography and magnetic resonance imaging in assessment of acute aortic syndromes显示文摘 | Macura KJ Szarf G Fishman EK | 2003 | Semin Ultrasound CT MR2003,24,: | 1 |
| 14 | Magnetic resonance imaging of pelvic floor defects in women 显示文摘 | Macura KJ | 2006 | Top Magn Reson Imaging2006,17,6: | 1 |
| 15 | Dynamic contrast- enhanced MRI of the breast: quantitative method for kinetic curve type assessment 显示文摘 | E1Khouli RH Macura KJ Jacobs MA | 2009 | AJR2009,193,4: | 1 |
| 16 | 3-T dynamic contrast- enhanced MRI of the breast: pharmaeokinetic parameters versus conventional kinetic curve analysis 显示文摘 | El Khouli RH Macura KJ Kamel IR | 2011 | AJR Am J Roentgenol2011,197,6: | 1 |
| 17 | Comparison of Prostate-Specific Membrane Antigen-Based 18F-DCFBC PET/CT to Conventional Imaging Modalities for Detection of Hormone-Naive and Castration-Resistant Metastatic Prostate Cancer显示文摘 | Rowe SP Macura KJ Ciarallo A | 2016 | J Nucl Med2016,57,1: | 1 |
| 18 | Three-dimensional shape differences in the bony pelvis of women with pelvic floor disorders 显示文摘 | Brown KM Handa VL Macura K J | 2013 | Int Urogynecol J2013,24,3: | 1 |
| 19 | Advanced solution of SIP communication server with a new ap- proach to management 显示文摘 | MIROSLAV VOZNAK JIRI SLACHTA LUKAS MACURA | 2015 | Telecommunication Systems2015,59,4: | 1 |
| 20 | Patterns of enhancement on breast MR images: interpretation and imaging pitfalls 显示文摘 | Macura KJ Ouwerkerk R Jacobs MA | 2006 | Radio- graphics2006,26,6: | 1 |