|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Long-term follow-up after complete ablation of Barrett's esophagus with argon plasma coagulation显示文摘AIM: To report the long-term outcome of patients after complete ablation of non-neoplastic Barrett's esophagus (BE) with respect to BE relapse and development of intraepithelial neoplasia or esophageal adenocarcinoma.METHODS: In 70 patients with histologically proven nonneoplastic BE, complete BE ablation was achieved by argon plasma coagulation (APC) and high-dose proton pump inhibitor therapy (120 mg omeprazole daily). Sixty-six patients (94.4%) underwent further surveillance endoscopy. At each surveillance endoscopy four-quadrant biopsies were taken from the neo-squamous epithelium at 2 cm intervals depending on the pre-treatment length of BE mucosa beginning at the neo-Z-line, and from any endoscopically suspicious lesion.RESULTS: The median follow-up of 66 patients was 51 mo (range 9-85 mo) giving a total of 280.5 patient years.A mean of 6 biopsies were taken during surveillance endoscopies. In 13 patients (19.7%) tongues or islands suspicious for BE were found during endoscopy. In 8 of these patients (12.1%) non-neoplastic BE relapse was confirmed histologically giving a histological relapse rate of 3% per year. In none of the patients, intraepithelial neoplasia nor an esophageal adenocarcinoma was detected.Logistic regression analysis identified endoscopic detection of islands or tongues as the only positive predictor of BE relapse (P = 0.0004).CONCLUSION: The long-term relapse rate of nonneoplastic BE following complete ablation with high-power APC is low (3% per year). | Ahmed Madisch Stephan Miehike Ekkehard Bayerdoerffer Birgit Wiedemann David Antos Anke Sievert Michael Vieth Manfred Stolte Heinrich Schulz | 2005 | World Journal of Gastroenterology2005，11，8： | 14 |
| 2 | Is there an association of microscopic colitis and irritable bowel syndrome-A subgroup analysis of placebo-controlled trials显示文摘TO THE EDITOR
With great interest we read the recent retrospectice study by Barta et al (1) dealing with the clinical presentation of patients with microscopic colitis. They investigated in a cohort of 53 patients with microscopic colitis (46 with collagenous colitis, 7 with lymphocytic colitis)the relationship between microscopic colitis and both constipation and diarrhea. One of their mean finding was that abdominal pain, diarrhea and constipation was a common symptom complex of patients with microscopic colitis, thus the face of microcopic colitis resembles the subgroups of irritable bowel syndrome (IBS). | Ahmed Madisch Birgit Bethke Manfred Stolte Stephan Miehlke | 2005 | World Journal of Gastroenterology2005，11，41： | 4 |
| 3 | Helicobacter pyloriin gastric corpus of patients 20 years after partial gastric resection显示文摘AIM: To determine the long-term prevalence of Helicobacter pylori (H pylori) gastritis in patients after partial gastric resection due to peptic ulcer, and to compare the severity of Hpylori-positive gastritis in the corpus mucosa between partial gastrectomy patients and matched controls.METHODS: Endoscopic biopsies were obtained from 57 patients after partial gastric resection for histological examination using hematoxylin/eosin and Warthin-Starry staining. Gastritis was graded according to the updated Sydney system. Severity of corpus gastritis was compared between H pylori-positive partial gastrectomy patients and H pylori-positive duodenal ulcer patients matched for age and gender.RESULTS: In partial gastrectomy patients, surgery was performed 20 years (median) prior to evaluation. In 25 patients (43.8%) H pyloriwas detected histologically in the gastric remnant. Gastric atrophy was more common in H pylori-positive compared to H pylori-negative partial gastrectomy patients (P<0.05). The severity of corpus gastritis was significantly lower in H pylori-positive partial gastrectomy patients compared to duodenal ulcer patients (P<0.01). There were no significant differences in the activity of gastritis, atrophy and intestinal metaplasla between the two groups.CONCLUSION: The long-term prevalence of H pylori gastritis in the gastric corpus of patients who underwent partial gastric resection due to peptic ulcer disease is comparable to the general population. The expression of Hpylori gastritis in the gastric remnant does not resemble the gastric cancer phenotype. | Christian Kirsch Ahmed Madisch Petja Piehler Ekkehard Bayerdrffer Manfred Stolte Stephan Miehlke | 2004 | World Journal of Gastroenterology2004，10，17： | 3 |
| 4 | Management of functional dyspepsia: Unsolved problems and new perspectives显示文摘The common characteristic criteria of all functional gastrointestinal(GI)disorders are the persistence and recurrence of variable gastrointestinal symptoms that cannot be explained by any structural or biochemical abnormalities. Functional dyspepsia (FD) represents one of the important GI disorders in Western countries because of its remarkably high prevalence in general population and its impact on quality of life. Due to its dependence on both subjective determinants and diverse country-specific circumstances, the definition and management strategies of FD are still variably stated.Clinical trials with several drug classes (e.g., proton pump inhibitors, H2-blockers, prokinetic drugs) have been performed frequently without validated diseasespecific test instruments for the outcome measurements.Therefore, the interpretation of such trials remains difficult and controversial with respect to comparability and evaluation of drug efficacy, and definite conclusions can be drawn neither for diagnostic management nor for efficacious drug therapy so far. In view of these unsolved problems, guidelines both on the clinical management of FD and on the performance of clinical trials are needed. In recent years, increasing research work has been done in this area. Clinical trials conducted in adequately diagnosed patients that provided validated outcome measurements may result in better insights leading to more effective treatment strategies.Encouraging perspectives have been recently performed by methodologically well-designed treatment studies with herbal drug preparations. Herbal drugs, given their proven efficacy in clinical trials, offer a safe therapeutic alternative in the treatment of FD which is often favored by both patients and physicians. A fixed combination of peppermint oil and caraway oil in patients suffering from FD could be proven effective by well-designed clinical trials. | Ahmed Madisch Stephan Miehlke Joachim Labenz | 2005 | World Journal of Gastroenterology2005，11，42： | 3 |
| 5 | Reliability and validity of the Gastrointestinal Symptom Rating Scale(GSRS) and Quality of Life in Re- flux and Dyspepsia (QOLRAD) questionnaire in dyspepsia :a six-country study显示文摘 | Kulich KR Madisch A Pacini F | 2008 | Health Qual Life Outcomes2008，6，： | 1 |
| 6 | Phylogenetic analysis of the main neutralization and hemagglutination determinants of all human adenovirus prototypes as a basis for molecular classification and taxonomy显示文摘 | Madisch I Harste G Pommer H | 2005 | J Virol2005，79，15： | 1 |
| 7 | Impact of reflux disease on general and disease - related quality of life - evidence from a recent comparative methodological study in Germany 显示文摘 | Madisch A Kulich KR Malfertheiner P | 2003 | Z Gastroenterol2003，41，12： | 1 |
| 8 | Phylogenetic analysis and structural predictions ofhumanadenovirus penton proteins asa basis for tissuespecific adenovirus vector design显示文摘 | Madisch I Hofmayer S Moritz C | 2007 | J Virol2007，81，： | 1 |
| 9 | Intrinsic respiratory gating in small-animal CT显示文摘 | Soenke H. Bartling Julien Dinkel Wolfram Stiller Michael Grasruck Ijad Madisch Hans-Ulrich Kauczor Wolfhard Semmler Rajiv Gupta Fabian Kiessling | 2008 | European Radiology2008，，7： | 1 |
| 10 | Phylogenetic analysis of the main neutralization and hemagglutination determinants of all human adenovirus prototypes as a basis for molecular classification and taxono- my显示文摘 | MADISCH I HARSTE G POMMER H | 2005 | J Virol2005，79，15： | 1 |
| 11 | Phylogenetic analysis of the main neutralization and hemagglutination determinants of all human adenovirus prototypes as a basis for molecular classification and taxonomy 显示文摘 | Madisch I Harste G Pommer H | 2005 | J Virol2005，79，15： | 1 |
| 12 | Treatment of functional dyspepsia with a herbal preparation 显示文摘 | Madisch A Holtmann G Mayr G | 2004 | Digest2004，69，： | 1 |
| 13 | Oral budesonide therapy improves quality of life in patients with collagenous colitis显示文摘 | Ahmed Madisch Peter Heymer Claudia Voss Bernd Wigginghaus Elke B?stlein Ekkehard Bayerd?rffer Eberhard Meier Wolfgang Schimming Birgit Bethke Manfred Stolte Stephan Miehlke | 2005 | International Journal of Colorectal Disease2005，，4： | 1 |
| 14 | Budesonide is effective in treating lymphocytic colitis: a randomized double-blind placebo-con- trolled study 显示文摘 | Miehlke S Madisch A Karimi D | 2009 | Gastroenterology2009，136，7： | 1 |
| 15 | Phylogenetic analysisand structural predictions of human adenovirus penton proteins as a basis for tissue-specific adenovirus vector design 显示文摘 | Madisch I Hofmayer S Moritz C | 2007 | J Virol2007，81，15： | 1 |
| 16 | Oneweek triple therapy with esomeprazole, levofloxacin and amoxicillin is effective for eradication of Helicobacter pylori sensitive or resistant to metronidazole and/or clarithromycin 显示文摘 | Miehlke S Madisch A Bastlein E | 2003 | Helicobacter2003，8，： | 1 |
| 17 | Boswellia serrata extract for the treatment of collagenous colitis. A double-blind, randomized, placebo-controlled, multicenter trial显示文摘 | Ahmed Madisch Stephan Miehlke Otto Eichele Jenny Mrwa Birgit Bethke Eberhard Kuhlisch Elke B?stlein Georg Wilhelms Andrea Morgner Bernd Wigginghaus Manfred Stolte | 2007 | International Journal of Colorectal Disease2007，，12： | 1 |
| 18 | Phylogenetic analysis of the main neutralization and hemagglutination determinanits of all human adenovirus prototypes as a basis for molecular classification and taxonomy显示文摘 | Madisch I Harste G Pommer H | | 0，，24： | 1 |
| 19 | Phylogenetic analysis and structural predictions of human adenovirus penton proteins as a basis for tissue- specific adenovirus vector design 显示文摘 | Madisch I Hofmayer S Moritz C | 2007 | J Virol2007，81，15： | 1 |
| 20 | Antiviral activity of cidofovir and ribavirin against the new human adenovirus subtype 14a that is associated with severe pneumonia显示文摘 | Darr S Madisch I Heim A | | 0，，05： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员