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| 1 | Terlipressin and hepatorenal syndrome: What is important for nephrologists and hepatologists显示文摘Hepatorenal syndrome (HRS) is a reversible form of functional renal failure that occurs with advanced hepatic cirrhosis and liver failure. Despite mounting research in HRS, its etiology and medical therapy has not been resolved. HRS encompasses 2 distinct types. Type 1 is characterized by the rapid development of renal failure that occurs within 2 wk and involves a doubling of initial serum creatinine. Type 2 has a more insidious onset and is often associated with ascites. Animal studies have shown that both forms, in particular type 1 HRS, are often precipitated by bacterial infections and cir-culatory changes. The prognosis for HRS remains very poor. Type 1 and 2 both have an expected survival time of 2 wk and 6 mo, respectively. Progression of liver cir-rhosis and the resultant portal hypertension leads to the pooling of blood in the splanchnic vascular bed. The ensuing hyperdynamic circulation causes an ineffective circulatory volume which subsequently activates neuro-hormonal systems. Primarily the sympathetic nervoussystem and the renin angiotensin system are activated, which, in the early stages of HRS, maintain adequate circulation. Both advanced cirrhosis and prolonged ac-tivation of neurohormonal mechanisms result in fatal complications. Locally produced nitric oxide may have the potential to induce a deleterious vasodilatory effect on the splanchnic circulation. Currently medical therapy is aimed at reducing splanchnic vasodilation to resolve the ineffective circulation and maintain good renal per-fusion pressure. Terlipressin, a vasopressin analogue, has shown potential benefit in the treatment of HRS. It prolongs both survival time and has the ability to re-verse HRS in the majority of patients. In this review we aim to focus on the pathogenesis of HRS and its treatment with terlipressin vs other drugs. | Ahmed A Magan Atif A Khalil Mohamed H Ahmed | 2010 | World Journal of Gastroenterology2010，16，41： | 11 |
| 2 | Influence of antiviral therapy in the long‐term outcome of recurrent hepatitis C virus infection following liver transplantation显示文摘 | A. García‐Reyne C. Lumbreras I. Fernández F. Colina M. Abradelo P. Magan R. San‐Juan A. Manrique F. López‐Medrano A. Fuertes M. Lizasoain E. Moreno J.M. Aguado | 2013 | Transpl Infect Dis2013，，4： | 2 |
| 3 | Milk-sense: a volatile sensing system reeognises spoilage bacteria and yeasts in milk显示文摘 | MAGAN N PAVLOU A CHRYSANTHAKIS I | 2001 | Sensors and Actuators B-Chemical2001，72，1： | 1 |
| 4 | European research on ochratoxin A in grapes and wine显示文摘 | Battilani P Magan N Logrieco A | 2006 | Int J Food Microbiol2006，111，： | 1 |
| 5 | Recognition of anaerobic bacterial isolates in vitro using electronic nose technology显示文摘 | Pavlou A Turner A P F Magan N | 2002 | Letters in applied microbiology2002，35，5： | 1 |
| 6 | Electronic Noses and Disease Diagnostics显示文摘 | Turner A P F Magan N | 2004 | Nature Reviews Microbiology2004，2，： | 1 |
| 7 | Soil volatile fingerprints: use for discrimination between soil types under different environmental conditions 显示文摘 | Bastos A C Magan N | 2007 | Sensors and Actuators2007，125，2： | 1 |
| 8 | Association of simvastatin and hyperlipidemia with periodontalstatus and bone metabolism markers 显示文摘 | MAGAN FERNANDEZ A PAPAY RAMIREZ L TOMAS J etal | 2014 | J Periodontol2014，85，10： | 1 |
| 9 | Evaluation and management of injuries of the tibiofibular syndesmosis 显示文摘 | Magan A Golano P Maffulli N Khanduja V | 2014 | British medical bulletin2014，111，1： | 1 |
| 10 | Smoking and periodontal disease severity显示文摘 | Martinez-Canut P Lorca A Magan R | 1995 | J Clin Periodontol1995，22，： | 1 |
| 11 | Evaluation and management of injuries of the tibiofibular syndesmosis显示文摘 | Magan A Golano P Maffulli N Khanduja V | 2014 | Br Med Bull2014，111，1： | 1 |
| 12 | Recognition of anaerobic bacterial isolates in vitro using electronic nose technology显示文摘 | Pavlou A Turner A R F Magan N | 2002 | Letters in Applied Microbiology2002，35，： | 1 |
| 13 | Milk-sense:a volatile sensing system recognises spoilage bacteria and yeasts in milk 显示文摘 | Magan N Pavlou A Chrysanthakis I | 2001 | Sensors and Actuators B-Chemical2001，72，1： | 1 |
| 14 | Fumonisin-producing strains of Fusatium: a review of their ecophysiology显示文摘 | Marin S Magan N Ramos A J | 2004 | Journal of Food Pro- tection2004，67，8： | 1 |
| 15 | Milk-sense: a volatile sensing system recognises spoilage bacteria and yeasts in milk显示文摘 | MAGAN N PAVLOU A CHRYSANTHAKIS I | 2001 | Sensors and Actuators B-Chemical2001，72，1： | 1 |
| 16 | Milk-sense: a volatile sensing system recognises spoilage bacteria and yeasts in milk显示文摘 | MAGAN N PAVLOU A CHRYSANTHAKIS I | 2001 | Sensors and Actuators B2001，72，： | 1 |
| 17 | Uniqueness and growth of solutions in two-temperature generalized ther-moelastic theories显示文摘 | Magan¨e A Quintanilla R | 2009 | Journal of Mathematics and Mechanics of Solids2009，14，7： | 1 |
| 18 | Trametes Versicolor: Potential for Atrazine Bioremediation in Calcareous Clay Soil, under Low Water Availability Conditions显示文摘 | Bastos A C Magan N | 2009 | International Biodeterioration &Biodegradation2009，63，4： | 1 |
| 19 | Synthesis and anti-inflammatory activityevaluation of some acridinyl amino antipyrine,acridinyl amino anthraquinone,acridino thiourea and thiazolino thiourea derivatives显示文摘 | Magan A Sondhi SM Singh R P | 1990 | Indian ChemSoc1990，67，6： | 1 |
| 20 | An intelligent rapid odour recognition model in discrimination of Helicobacter pylori and other gastroesophageal isolates in vitro 显示文摘 | Pavlou A K Magan N Sharp D | 2000 | Biosensors and Bioelectronics2000，15，78： | 1 |
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