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| 1 | Potential antibacterial activity of berberine against multi drug resistant enterovirulent Escherichia coli isolated from yaks(Poephagus grunniens) with haemorrhagic diarrhoea显示文摘Objective:To evaluate the antimicrobial efficacy of berberine,a plant alkaloid.Methods:Five multi-drug resistant(MDR) STEC/EPEC and five MDR ETEC isolates from yaks with haemorrhagic diarrhoea were selected for the study.Antibacterial activity of berberine was evaluated by broth dilution and disc diffusion methods.The binding kinetics of berberine to DNA and protein was also enumerated.Results:For both categories of enterovirulent Escherichia coli(E.roli) isolates, berberine displayed the antibaclerial effect in a dose dependent manner.The MIC50 of berberine chloride for STEC/EPEC isolates varied from 2.07μM to 3.6μM with a mean of(2.95±0.33)μM where as for ETEC strains it varied from 1.75 to 1.96μM with a mean of(1.87±0.03)μM. Berberine bind more tightly with double helix DNA with Bmax and Kd of(24.68±2.62) and(357.8±57.8),respectively.Berberine reacted with protein in comparatively loose manner with Bmax and Kd of(18.9±3.83) and <286.2±113.6),respectively.Conclusions:The results indicate clearly that berberine may serve as a good antibacterial against multi drug resistant E.coli. | Samiran Bandyopadhyay Pabitra H Patra Achintya Mahanti Dipak K Mondal Premanshu Dandapat Subhasis Bandyopadhyay Indranil Samanta Chandan Lodh Asit K Bera Debasish Bhattacharyya Mihir Sarkar Kishore K Baruah | 2013 | Asian Pacific Journal of Tropical Medicine2013，6，4： | 11 |
| 2 | Comparative analysis of APACHE-Ⅱ and P-POSSUM scoring systems in predicting postoperative mortality in patients undergoing emergency laparotomy显示文摘BACKGROUND Laparotomy remains one of the commonest emergency surgical procedures.Early prognostic evaluation would aid in selecting the high-risk patients for an aggressive treatment.Awareness about risks could potentially contribute to the quality of perioperative care and optimum utilization of resources.Portsmouth modification of Physiological and operative severity for the enumeration of mortality and morbidity (P-POSSUM) and the acute physiology and chronic health evaluation Ⅱ(APACHE-Ⅱ) have been the most widely used scoring systems for emergency laparotomies.It is always better to have a single scoring system to predict outcomes and audit healthcare organizations.AIM To compare the ability of APACHE-II and P-POSSUM to predict postoperative morbidity and mortality in patients undergoing emergency laparotomy.METHODS All patients undergoing emergency laparotomy at the Tata Main Hospital,Jamshedpur between December 2013 and November 2014 were included in the study.In this observational study,P-POSSUM and APACHE-Ⅱ scoring were done,and the outcome analysis evaluated with mortality being the primary outcome.RESULTS For P-POSSUM,at a cut off value of 63 to predict mortality using receiver operating characteristics curve analysis,the area under the curve was 0.989;and for APACHE-Ⅱ,at the cut off value of 24,the area under the curve was 0.965.CONCLUSION Because the ability of APACHE-Ⅱ to predict mortality was similar to P-POSSUM and APACHE-Ⅱ does not need scoring for intra-operative findings and histopathology reports,APACHE-Ⅱ can be used pre-operatively to assess the risk in patients undergoing emergency laparotomy.However,for audit purposes,either of the two scoring systems can be used. | Deb Sanjay Nag Ankur Dembla Pratap Rudra Mahanty Shashi Kant Abhishek Chatterjee Devi Prasad Samaddar Parul Chugh | 2019 | World Journal of Clinical Cases2019，7，16： | 5 |
| 3 | Application of RBF neual network to fault classification and location in transmission lines显示文摘 | Mahanty R N Dutta Gupta P B | 2004 | IEEE Proceedings on Gen- eration Transmission and Distribution2004，151，2： | 1 |
| 4 | Electronic structure of Ga-, In-, and Tl-doped PbTe: A supercell study of the impurity bands显示文摘 | Hoang K Mahanti S D | 2008 | Physical Review B2008，78，8： | 1 |
| 5 | Synthesis of nanocrystalline Li4Ti5O12 by a novel aqueous combustion technique 显示文摘 | RAJA M W MAHANTY S KUNDU M | 2009 | J Alloys and Compounds2009，468，： | 1 |
| 6 | Cytokine production in acute versus chronic human Schistosomiasis mansoni: the cross- regulatory role of interferon- gamma and interleukin- 10 in the re- sponses of peripheral blood mononuclear cells and splenocytes to parasite antigens显示文摘 | Montenegro SM Miranda P Mahanty S et at | 1999 | J Infect Dis1999，179，6： | 1 |
| 7 | Vendor Selection Problem (VSP) Using Fuzzy Analytical Hierarchy Process(FAHP)显示文摘 | Kaur P Verma R Mahanti N C | 2008 | International Journal of Soft Computing2008，3，1： | 1 |
| 8 | Experience with the use ofsirolimus in liver transplantation-use in patients fothom calcineurin inhibitors are contraindicated显示文摘 | Chang J Mahanty H Quan D | 2000 | Liver Transpl2000，6，6： | 1 |
| 9 | Off- line/Realtime Traffic Classification Using Semi- Supervised Learning显示文摘 | ERMAN J MAHANTI A ARLITT M | 2007 | Performance Evalua- tion2007，64，9： | 1 |
| 10 | Electronic transport properties of PbTe and AgPbmSbTe2 + m systems 显示文摘 | BILC D MAHANTI S D KANATZIDIS M G | 2006 | Phys Rev B2006，74，12： | 1 |
| 11 | Impurity clus-tering and impurity-induced bands in PbTe-,SnTe-,and GeTe-based bulk thermoelectrics显示文摘 | Hoang K Mahanti S D Kanatzidis M G | | 0，，： | 1 |
| 12 | A high-throughput genomewalking method and its use for cloning unknown flanking sequences显示文摘 | Reddy P S Mahanty S Kanl T | 2008 | Anal Biochem2008，381，2： | 1 |
| 13 | Resonant states in the electronic structure of the high performance thermoelectries AgPbm SbTe2 + m :The role of Ag-Sb microstrnctures 显示文摘 | BILC D MAHANTI S D Quarez E | 2004 | Phys Rev Lett2004，93，14： | 1 |
| 14 | Pathogenesis of filoviral haemorrhagic fevers 显示文摘 | Mahanty S Bray M | 2004 | Lancet Infect D/s2004，4，8： | 1 |
| 15 | A novel data mining algorithm for semanticWeb based data cloud 显示文摘 | Lai K Mahanti N C | 2010 | International Journal of ComputerScience and Security (IJCSS)2010，4，2： | 1 |
| 16 | Application of RBF neural network to fault classification and location in transmission lines 显示文摘 | MAHANTY R N DUTrA G P B | 2004 | IEEE Pro- ceedings: Generation Transmission and Distribution2004，151，2： | 1 |
| 17 | A tale of the tails:power-laws in internet measurements显示文摘 | Mahanti A Carlsson N Arlitt M | 2013 | Network2013，27，1： | 1 |
| 18 | A calcineurin inhibitor-sparing regimen withsirolimus,mycophenolate mofetil,and anti-cd25 mab provides effective immunosuppression in kidney transplant recipients with delayed or impaired graft function显示文摘 | Chang G Mahanty H Vincenti F | 2000 | Clin Transplant2000，14，6： | 1 |
| 19 | Improved electrochemical performance of Li2MnSiO4/C composite synthesized by combustion technique显示文摘 | Ghosh P Mahanty S Basu R N | | 0，，08： | 1 |
| 20 | An analytic through- put model for TCP NewReno 显示文摘 | Parvez N Mahanti A Williamson C | 2010 | IEEE/ACM Transac- tions on Networking2010，18，2： | 1 |
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