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| 1 | Epidemiological transition of colorectal cancer in developing countries: Environmental factors, molecular pathways, and opportunities for prevention显示文摘Colorectal cancer(CRC)is one of the leading causes of cancer and cancer-related mortality worldwide.The disease has been traditionally a major health problem in industrial countries,however the CRC rates are increasing in the developing countries that are undergoing economic growth.Several environmental risk factors,mainly changes in diet and life style,have been suggested to underlie the rise of CRC in these populations.Diet and lifestyle impinge on nuclear receptors,on the intestinal microbiota and on crucial molecular pathways that are implicated in intestinal carcinogenesis.In this respect,the epidemiological transition in several regions of the world offers a unique opportunity to better understand CRC carcinogenesis by studying the disease phenotypes and their environmental and molecular associations in different populations.The data from these studies may have important implications for the global prevention and treatment of CRC. | Faraz Bishehsari Mahboobeh Mahdavinia Michele Vacca Reza Malekzadeh Renato Mariani-Costantini | 2014 | World Journal of Gastroenterology2014，20，20： | 18 |
| 2 | Mineralogical Evidence for Regional Metamorphism Overprinted by Contact Metamorphism显示文摘The Soursat metamorphic complex(SMC) in northwestern Iran is part of the Sanandaj-Sirjan metamorphic belt.The complex is composed of different metamorphic and plutonic rocks,but is dominated by metapelites composed of garnet,staurolite,kyanite,fibrolite,cordierite,and andalusite.Porphyroblasts in schists have the same fabric,and three stages of schistosity are present.The internal schistosity(Sn) inclusion trails are also offset by conjugate sets of extensional schistosity(Sn+1) and a second(Sn+2) that crenulates(Sn+1).Polyphase metamorphisms are present in the complex.Garnet,staurolite,kyanite,and fibrolite assemblage preserves conditions during the M1 metamorphic event.This assemblage yields a P-t estimate of 645±11°C and 6.5±0.5 kbar.Other samples of the central part of SMC contain cordierite and andalusite(M2) overgrowth that yields a P-t estimate of 532±33°C and 2.1±1.1 kbar. | Mahboobeh JAMSHIDI BADR Fariborz MASOUDI Alan S.COLLINS Ali SORBI | 2012 | Acta Geologica Sinica(English Edition)2012，86，1： | 3 |
| 3 | 突厥蔷薇提取物抗戊四唑所致小鼠痉挛的作用(英文)显示文摘目的:研究突厥蔷薇(Rosa damascena)的水提物、乙醇提取物及三氯甲烷提取物对戊四唑所致小鼠惊厥的作用。方法:实验动物按如下方案分组:生理盐水对照组,地西泮组(3mg/kg),水提物组(100,500和1000mg/kg),乙醇提取物组(100,500和1000mg/kg),三氯甲烷提取物组(100,500和1000mg/kg)。所有药物均在注射戊四唑30min前皮下注射。记录并比较各组小鼠阵发性强直性抽搐潜伏期、最小阵发性痉挛潜伏期及死亡率。结果:与生理盐水对照组相比,三组水提物组小鼠的阵发性强直性抽搐潜伏期及最小阵发性痉挛潜伏期均有延长(P<0.05或P<0.01);一组乙醇提取物组(1000mg/kg)小鼠的最小阵发性痉挛潜伏期及两组乙醇提取物组(500和1000mg/kg)小鼠的阵发性强直性抽搐潜伏期均有延长(P<0.05,P<0.01);三组三氯甲烷提取物组小鼠的阵发性强直性抽搐潜伏期及最小阵发性痉挛潜伏期无明显变化。不同提取物各组的死亡率与对照组相比无明显差异。结论:本研究的结果证实了突厥蔷薇具有抗戊四唑所致小鼠惊厥的作用,其具体作用机制有待进一步研究。 | Mahmoud Hosseini Mahboobeh Ghasemzadeh Rahbardar Hamid Reza Sadeghnia Hassan Rakhshandeh | 2011 | 中西医结合学报2011，9，10： | 3 |
| 4 | Biostratigraphy and Sequence Stratigraphy of the Gurpi Formation at Deh Dasht Area, Zagros Basin, SW Iran显示文摘A rich assemblage of planktonic foraminifera has been studied from an outcrop of the Gurpi Formation, the hydrocarbon source rock in the southwest Iran, Deh Dasht area(Kuh-e Siah anticline). Based on the distribution of the planktonic foraminifera, eight biozones have been recognized that included:Dicarinella concavata Interval Zone(Earliest Santonian), Dicarinella asymetrica Total Range Zone(Santonian to Earliest Campanian), Globotruncanita elevata Partial Range Zone(Early Campanian), Globotruncana ventricosa Interval Zone(Middle to Late Campanian), Radotruncana calcarata Total Range Zone(Late Campanian), Globotruncanella havanensis Partial Range Zone(Late Campanian), Globotruncana aegyptiaca Interval Zone(Late to latest Campanian), Gansserina gansseri Interval Zone(Latest Campanian to Early Maastrichtian). These biozones indicates that the Gurpi Formation deposited during the Early Santonian- Early Maastrichtian. These biozones are compared to the most standard biozones defined in Tethysian domain. Based on distribution of morphotype groups of planktonic foraminifera, planktonic to benthic ratio(P/B) and content of carbonate, nine third-order sequences are recognized. | Mahboobeh FEREYDOONPOUR Hossein VAZIRI-MOGHADDAM Azizollah TAHERI | 2014 | Acta Geologica Sinica(English Edition)2014，88，6： | 2 |
| 5 | Efficacy of the herbal formula of Foeniculum vulgare and Rosa damascena on elderly patients with functional constipation:A double-blind randomized controlled trial显示文摘Background:Constipation is a common chronic bowel disorder with an incidence of more than 50%in the elderly population.Complementary and alternative medicine is a cost-effective and satisfactory treatment for constipation used widely by the elderly.Objective:This study evaluates the efficacy of an herbal formula made from Foeniculum vulgare Mill.and Rosa damascena for the treatment of constipation in an elderly population and consequent changes to their quality of life.Design,setting,participants and intervention:This double-blind randomized active controlled clinical trial,with parallel group allocation ratio of 1:1,was conducted in a referral clinic in Afzalipour Hospital,affiliated to Kerman University of Medical Sciences in Kerman,Southeastern Iran.Individuals over 60 years of age,diagnosed with functional constipation(based on the RomeⅣcriteria),were included in this study.Participants received a sachet of 10 g F.vulgare and R.damascena(herbal formula group)or polyethylene glycol 4000(PEG 4000 group)with a glass of warm water two times a day for 4 weeks and were followed up for 4 additional weeks.Main outcome measures:Constipation severity,stool consistency,and the quality of life were used as the primary outcomes.Drug side effects were used as a secondary outcome.The outcomes were assessed using the Constipation Assessment Scale,the Bristol Stool Form Scale,and the Patient Assessment of Constipation Quality of Life questionnaire.Results:A total of 25 participants in each group completed the four-week treatment cycle and the eightweek follow-up.At the end of the four-week treatment cycle,all clinical outcomes had significant improvements in both groups(P<0.05).The analysis of constipation severity(P<0.001),stool consistency(P<0.001),and the quality of life(P<0.001)showed significant improvements with fewer side effects(mild diarrhea)and a longer duration of symptom relief in the herbal formula group compared to the PEG 4000 group.Conclusion:Although both interventions significantly improved the treatment outcomes,constipation severity,stool consistency and the quality of life were improved more effectively by the herbal formula than by PEG 4000;however,the mechanism of action is not yet understood.Trial registration:This trial was registered in the Iranian Registry of Clinical Trials(IRCTID:IRCT20200108046056N1). | Maryam Azimi Hanieh Niayesh Mahboobeh Raeiszadeh Sedigheh Khodabandeh-shahraki | 2022 | Journal of Integrative Medicine2022，20，3： | 2 |
| 6 | Cervical cancer preventioncer-vical screening: Science in evolution 显示文摘 | Mahboobeh S Diane S Philip E | 2007 | Obstetrics and Gynecol Clinics of North America2007，34，4： | 1 |
| 7 | Clean synthesis of novel spiro[indene-2,2'-[1,3,5]-oxathiazine]-1,3-diones in water显示文摘In this work,we have designed an efficient and convenient method for the synthesis of novel spiro[indene-2,2'-[1,3,5]oxathiazine]-1,3-diones by the one-pot,three component condensation of tetramethyl guanidine,ninhydrin,and isothiocyanates in water.Easy purification,green reaction conditions,easy performance and good yields are some advantages of this procedure. | Mahboobeh Salehpour Javad Azizian Hassan Kefayati | 2017 | Chinese Chemical Letters2017，28，5： | 1 |
| 8 | Ccrvical cancer prevention cervical screening:Science in evolution 显示文摘 | Mahboobeh S Diane S Philip E | 2007 | Obstetrics and Gynccol Clinics of North America2007，34，4： | 1 |
| 9 | Determination of lead, cadmium and arsenic in infusion tea cultivated in north of Iran显示文摘 | Sakine S Mahboobeh G Azita M | 2012 | Iranian Journal of Environmental Health Sciences & Engineering2012，9，： | 1 |
| 10 | Successful local and systemic medical treatment of cesarean scar pregnancy and a subsequent term pregnancy after treatment : a case series 显示文摘 | Reihaneh P Leila B Mahboobeh S | 2015 | Iran J Reprod Med2015，13，7： | 1 |
| 11 | Risk of precancerand follow-up management strategies for women with hu-man papillomavirus-negative atypical squamous cells ofundetermined significance显示文摘 | Mahboobeh S Diane S Sholom W | 2007 | Obstet Gynecol2007，109，6： | 1 |
| 12 | A neural network for predicting saturated liquid density using genetic algorithm for pure and mixed refrigerants 显示文摘 | Mohebbi Ali Taheri Mahboobeh Sohani Ataollah | 2008 | International Journal of Refrigeration2008，31，8： | 1 |
| 13 | Copper immobilized on nano-silica triazine dendrimer(Cu(11)-TD@n Si O2)catalyzed synthesis of symmetrical and unsymmetrical 1,3-diynes under aerobic conditions at ambient temperature显示文摘 | Mahboobeh N E Iraj M B Ahmad R K | 2014 | RSC Adv2014，4，14： | 1 |
| 14 | Are Shorter Article Titles More Attractive for Citations? Crosssectional Study of 22 Scientific Journals显示文摘 | Farrokh Habibzadeh Mahboobeh Yadollahie | 2010 | Croatian Medical Journal2010，，2： | 1 |
| 15 | Cervical cancer prevention cervical screening:Science in evolution显示文摘 | Mahboobeh S Diane S Philip E | 2007 | Obstetrics and Gynecol Clinics of North America2007，34，4： | 1 |
| 16 | Effect of benzene on the cerebellar structure and behavioral characteristics in rats显示文摘Objective: To investigate the effects of benzene on rat's cerebellum structure and behavioral characteristics, including anxiety and motor impairment.Methods: Twenty rats were randomly allocated into two groups orally receiving distilled water and benzene(200 mg/kg/day). A total of 10 rats were used at the beginning of benzene exposure. Two rats died during benzene treatment and 8 rats remained for evaluation of the behavioral test and finally 6 rats underwent histological assessment. At the end of the 4th week, motor function and anxiety were evaluated in rotarod test and elevated plus maze, respectively. Besides, the cerebellum was dissected for structural assessment using stereological methods.Results: Performance of the benzene-treated rats in fixed and accelerating speed rotarod was impaired and their riding time(endurance) was lower compared to the control group(P = 0.02). The benzene-treated rats also spent less time in the open arms and had fewer entrances to the open arms in comparison to the control group, indicating anxiety(P = 0.01). The total volume of the cerebellar hemisphere, its cortex, intracerebellar nuclei, total number of the Purkinje, Bergmann, Golgi, granule, neurons and glial cells of the molecular layer, and neurons and glial cells of the intracerebellar nuclei were reduced by 34%-76% in the benzene-treated rats in comparison to the distilled water group(P = 0.003). The most cell loss was seen in Bergmann glia. Conclusions: The structure of cerebellum altered after benzene treatment. In addition, motor impairment and anxiety could be seen in benzene-treated rats. | Ali Rafati Mahboobeh Erfanizadeh Ali Noorafshan Saied Karbalay-Doust | 2015 | Asian Pacific Journal of Tropical Biomedicine2015，5，7： | 1 |
| 17 | The effect of distraction on the intensity of children pain during burn dressing显示文摘 | Mahboobeh N | 2004 | The Suffering Child2004，5，2： | 1 |
| 18 | Prevalence of Helicobacter Pylori Infection in Patients withDigestive Complaints Using Urea Breath Test inMashhad,Northeast Iran 显示文摘 | Mahboobeh Nakhaei Moghaddam | 2010 | JRItS2010，10，2： | 1 |
| 19 | The effect of shot peening on fatigue and corrosion behavior of 316L stainless steel in Ringer's solution显示文摘 | Azar V Hashemi B Mahboobeh Rezaee Yazdi | 2010 | Surface and Coating Technology2010，204，21： | 1 |
| 20 | Incidence and age distribution of colorectal cancer in Iran: Results of a population-based cancer registry显示文摘 | Reza Ansari Mahboobeh Mahdavinia Alireza Sadjadi Mehdi Nouraie Farin Kamangar Faraz Bishehsari Hafez Fakheri Shahriar Semnani Shahnam Arshi Mohammad-Javad Zahedi Sodeif Darvish-Moghadam Fariborz Mansour-Ghanaei Alireza Mosavi Reza Malekzadeh | 2005 | Cancer Letters2005，，1： | 1 |
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