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| 1 | Contrast-enhanced harmonic endoscopic ultrasound is able to discriminate benign submucosal lesions from gastrointestinal stromal tumors显示文摘 | Klaus Kannengiesser Reiner Mahlke Frauke Petersen Anja Peters Matthias Ross Torsten Kucharzik Christian Maaser | 2012 | Scandinavian Journal of Gastroenterology2012，，12： | 3 |
| 2 | Hemoconcentration : an early marker of severe and/ornecrotizing pancreatitis? A critical appraisal 显示文摘 | Lankisch PG Mahlke R Blum T | 2001 | Am JGastroenterol2001，96，7： | 1 |
| 3 | A simulated annealing algorithm for transient optimization in gas networks显示文摘 | Mahlke D Martin A Moritz S | 2007 | Mathematical Methods of Op- erations Research2007，66，1： | 1 |
| 4 | Usability, aesthetics and emotions in human-technology interaction 显示文摘 | Thuring M Mahlke S | 2007 | International Journal of Psychology2007，42，4： | 1 |
| 5 | Instant evaluation of contrast enhanced endoscopic ultrasound helps to differentiate various solid pancreatic lesions in daily routine显示文摘BACKGROUND Contrast enhanced harmonic endoscopic ultrasound(CEH-EUS) is a spreading technique; some studies have shown its value in the diagnosis of pancreatic adenocarcinoma using quantitative analysis.AIM To examine the value of CEH-EUS for differentiating various pancreatic lesions in everyday routine with qualitative and quantitative analysis.METHODS Data of 55 patients with pancreatic lesions who underwent CEH-EUS were analysed retrospectively. Perfusion characteristics were classified by the investigator qualitatively immediately upon investigation, quantitative analysis was performed later on. Samples from fine needle aspiration(EUS-FNA) or surgical specimen served as gold standard.RESULTS CEH-EUS showed 39 hypoenhanced lesions, 3 non-enhanced and 13 hyperenhanced lesions. Concordance of the investigators qualitative classification of peak contrast enhancement with quantitative analysis later on was 100%, while other parameters such as arrival time, time to peak or area under the curve did not show additional value. 34 of 39 hypoenhanced lesions were pancreatic adenocarcinoma; of the hyperenhanced lesions 4 were inflammatory, 3 neuroendocrine carcinomas, 1 lymphoma, 1 insulinoma and 4 metastases(2 of renal cell carcinoma, 2 of lung cancer). Non-enhanced lesions showed up as necroses. Sensitivity for the detection of pancreatic adenocarcinoma was 100%,specificity 87.2% for hypoenhancement alone; in otherwise healthy pancreatic tissue all hypoenhanced lesions were pancreatic adenocarcinoma(sensitivity and specificity 100%, PPV and NPV for adenocarcinoma 100%).CONCLUSION This study again shows the excellent value of CEH-EUS in everyday routine for diagnostics of various focal pancreatic lesions suggesting that qualitatively assessed hypoenhancement is highly predictive for adenocarcinoma. Additional quantitative analysis of perfusion parameters does not add diagnostic yield. In case of the various hyperenhanced pancreatic lesions in our data set, histologic sampling is essential for further treatment. | Klaus Kannengiesser Reiner Mahlke Frauke Petersen Anja Peters Torsten Kucharzik Christian Maaser | 2019 | World Journal of Clinical Cases2019，7，1： | 1 |
| 6 | The superblock: an effective technique for VLIW and superscalar compilation 显示文摘 | HWU W W MAHLKE S A CHEN W Y | 1993 | The Journal of Supercomputing1993，7，12： | 1 |
| 7 | The Importance of Prepass Code Scheduling for Superscalar and Superpipelined Processors显示文摘 | Lavery D M Chang P P Mahlke S A | 1995 | IEEE Transactions on Computers1995，44，3： | 1 |
| 8 | Hemoconcentrationl:an early marker of severe and/or necrotizing pancreatitis? a critical appraisa1显示文摘 | Lankisch PC Mahlke R Blum T | 2001 | Am J Gastroenterol2001，96，7： | 1 |
| 9 | Sentinel scheduling: A model for compiler-controlled speculative execution 显示文摘 | Mahlke S A Chen W Y Bringmann R A | 1993 | ACM Trans on Computer Systems1993，11，4： | 1 |
| 10 | Hemoconcentration:an early marker of severe and/or necrotizing pancreatitis? A critical appraisal显示文摘 | Lankisch PG Mahlke R Blum T | 2001 | Am J Gastroenterol2001，96，7： | 1 |
| 11 | Hemoconcentration:an early marker of severe and/or necrotizing pancreatitis?A critical appraisal显示文摘 | Lankisch PG Mahlke R BlumT | 2001 | Am J Gastroenterol2001，96，7： | 1 |
| 12 | The superblock:an effective technique for VLIW and superscalar compilation显示文摘 | W W Hwu S A Mahlke W Y Chen | 1993 | The Journal of Supercomputing 71993，，： | 1 |
| 13 | Pivotal role of oligomerization in expanded polyglutamine neurodegenerative disorders显示文摘 | Sanchez I Mahlke C Yuan J | 2003 | Nature2003，421，： | 1 |
| 14 | Contrast-enhanced harmonic endoscopic ultrasound is able to discriminate benign submucosal lesions from gastrointestinal stromal tumors显示文摘 | Klaus Kannengiesser Reiner Mahlke Frauke Petersen Anja Peters Matthias Ross Torsten Kucharzik Christian Maaser | 2012 | Scandinavian Journal of Gastroenterology2012，，12： | 1 |
| 15 | The superblock: an effective technique for VLIW and superscalar compilation显示文摘 | Hwu W M Mahlke S A Chen W Y | 1993 | The J of Supercomputing1993，7，12： | 1 |
| 16 | Effective compiler supoort for predicated execution using the hyperblock显示文摘 | Mahlke S A Lin D C Chen W Y | 1992 | ACM SIGMICRO Newsletter1992，23，12： | 1 |
| 17 | Automated custom instruction generation for domain-specific processor acceleration 显示文摘 | Clark N T Zhong H T Mahlke S A | 2005 | IEEE Transactions on Computers2005，54，10： | 1 |
| 18 | Barrier screws increase melt homogeneity显示文摘 | J Wortberg W Mahlke N Effen | 1994 | Kunststoffe1994，84，9： | 1 |
| 19 | Using Profile Information to Assist Classic Code Optimizations显示文摘 | Mahlke S | 1991 | Software Practice and Experience1991，21，12： | 1 |
| 20 | The superblock: An effective technique for VLIW and superscalar compilation 显示文摘 | Hwu W W Mahlke S A Chen W Y et aI | 1993 | Journal of Supereomputing1993，7，12： | 1 |
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