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| 1 | Role of liver transplantation in the management of hepatoblastoma in the pediatric population显示文摘Hepatoblastoma(HB) is the most common primary liver tumor in children and accounts for two-thirds of all malignant liver neoplasms in the pediatric population. For patients with advanced HB(unresectable or unresponsive to chemotherapy), combined treatment with chemotherapy and liver transplantation is an excellent option. The etiology of HB is mostly obscure because of its extreme rarity although some inherited syndromes and very low birth weight have been associated with it. The prognosis for children with HB has significantly improved in the past three decades thanks to advancements in chemotherapy, surgical resection and postoperative care. In 2002 a surgical staging system called pretreatment extent of disease(PRETEXT) was designed to allow a universal, multidisciplinary approach to patients with HB. Between one-third to two-thirds of patients initially present with unresectable tumors or distant metastases, but up to 85% of these tumors become operable after neoadjuvant chemotherapy. Patients with PRETEXT categories 1, 2, and some 3 are referred for neoadjuvant chemotherapy followed by surgical resection with the goal of complete tumor removal. Classic treatments regimens include a combination of cisplatin, fluorouracil, and vincristine or cisplatin and doxorubicin. Liver transplantation is the only treatment option for unresectable HB. In 2010 the pediatric end-stage liver disease, a pediatric-specific scoring system that determines a patient's ranking on the liver transplant list, began to award additional 'exception' points for patients with HB. We analyzed the Standard Transplant Analysis and Research dataset to assess the impact of changes in exception point criteria for HB on outcomes after liver transplantation at Texas Children's Hospital in Houston, Texas. We found that patients who were listed for transplantation with current HB exception criteria experienced a shorter waitlist time but survival was similar between the two eras. | Saira Khaderi Jacfranz Guiteau Ronald T Cotton Christine O'Mahony Abbas Rana John A Goss | 2014 | World Journal of Transplantation2014,4,4: | 23 |
| 2 | Chemotherapy options in elderly and frail patients with metastatic colorectal cancer (MRC FOCUS2): an open-label, randomised factorial trial显示文摘 | Matthew T Seymour Lindsay C Thompson Harpreet S Wasan Gary Middleton Alison E Brewster Stephen F Shepherd M Sinead O’Mahony Timothy S Maughan Mahesh Parmar Ruth E Langley | 2011 | The Lancet2011,,9779: | 2 |
| 3 | Tooth size discrepan- cies in Irish rthodontic patients among different malocclusion groups显示文摘 | O'Mahony G Millett T Barry MK | 2011 | Angle Orthod2011,81,1: | 1 |
| 4 | Identification of two distinct bovine parainfluenza virus type 3 genotypes显示文摘 | Horwood P F Gravel J L Mahony T J | 2008 | Journal of General Virology2008,89,: | 1 |
| 5 | Recurrence of fetal macrosomia in non-diabetic pregnancies显示文摘 | Walsh C A Mahony R T Foley M E | 2012 | J Obstet Gynecol2012,27,4: | 1 |
| 6 | Model equations for long waves in nonlinear dispersive systems 显示文摘 | Benjamin T B F R S Bona J L Mahony J J | 1972 | Philos Trans R Soc London: Ser A1972,272,: | 1 |
| 7 | Model equations for long waves in nonlinear dispersive systems显示文摘 | BENJAMIN R T BON J L MAHONY J J | 1972 | Philos Trans Roy Soc London1972,272,: | 1 |
| 8 | Stabilityand reproducibility of low-temperature anaerobic biological wastewater treatment显示文摘 | Collins G Mahony T O Flaherty V | 2006 | FEMS Microbiology Ecology2006,55,44: | 1 |
| 9 | Genetic an alysis of bovine viral diarrhoeaviruses from Australia显示文摘 | Mahony T J Mc Carthy F M Gravel J L | 2005 | Vet Microbiol2005,106,: | 1 |
| 10 | Genetic analysis of bovine viral diarrhoea viruses from Australia显示文摘 | Mahony T J McCarthy F M Gravel J L | 2005 | Vet Microbiol2005,106,: | 1 |
| 11 | Multiplex real-time RT-PCR detec- tion of three viruses associated with the bovine respiratory dis- ease complex 显示文摘 | Horwood P F Mahony T J | 2011 | J Virol Methods2011,171,2: | 1 |
| 12 | Nonlinear complementary filters on the special orthogonal group显示文摘 | MAHONY R HAMEL T PFLIMLIN J | | 0,,5: | 1 |
| 13 | Emergency planning and thecontrol of major accident hazards directive:Anapproach to determine the public safety zone fortoxic cloud releases显示文摘 | O’Mahony M T | 2008 | Journal of HazardousMaterials2008,154,35: | 1 |
| 14 | Maternal separation as a model of brain-gut axis dysfunction显示文摘 | O'Mahony S M Hyland N P Dinan T G | 2011 | Psychopharmacology (Berl)2011,214,1: | 1 |
| 15 | Decomposition of Ireland's carbon emissions from 1990 to 2010: An extended Kaya identity显示文摘 | Mahony T O | 2013 | Energy Policy2013,59,: | 1 |
| 16 | Landing a VTOL unmanned aerial vehicle on a moving platform u- sing optical flow显示文摘 | HERISSE B HAMEL T MAHONY R | 2012 | IEEE Transactions on Robotics2012,28,1: | 1 |
| 17 | Model equations for long waves in nonlinear dispersive systems显示文摘 | Benjamin T B Bona J I Mahony J J | 1972 | Phil Trans R Soc (London)1972,272,: | 1 |
| 18 | Robust trajectory tracking for a scale model autonomous helicopter 显示文摘 | Mahony R Hamel T | 2004 | InternationalJournal of Robust and Nonlinear Control2004,14,12: | 1 |
| 19 | The driving forces of change in energy-related CO2 emissions in Ireland: A multi-sectoral decomposition from 1990 to 2007显示文摘 | O Mahony T Zhou P Sweeney J | 2012 | Energy Policy2012,44,0: | 1 |
| 20 | Model equation for long water waves in nonlinear dispersive systems显示文摘 | Benjamin T B Bona J L Mahony J J | 1972 | Philos Royal Soe London Series A1972,272,: | 1 |