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11篇 您的检索式:作者名="Majundar"
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1Genetically modified mouse models for the study of nonalcoholic fatty liver disease显示文摘Nonalcoholic fatty liver disease(NAFLD) is associated with obesity,insulin resistance,and type 2 diabetes.NAFLD represents a large spectrum of diseases ranging from(1) fatty liver(hepatic steatosis);(2) steatosis with inflammation and necrosis;to(3) cirrhosis.The animal models to study NAFLD/nonalcoholic steatohepatitis(NASH) are extremely useful,as there are still many events to be elucidated in the pathology of NASH.The study of the established animal models has provided many clues in the pathogenesis of steatosis and steatohepatitis,but these remain incompletely understood.The different mouse models can be classified in two large groups.The first one includes genetically modified(transgenic or knockout) mice that spontaneously develop liver disease,and the second one includes mice that acquire the disease after dietary or pharmacological manipulation.Although the molecular mechanism leading to the development of hepatic steatosis in the pathogenesis of NAFLD is complex,genetically modified animal models may be a key for the treatment of NAFLD.Ideal animal models for NASH should closely resemble the pathological characteristics observed in humans.To date,no single animal model has encompassed the full spectrum of human disease progression,but they can imitate particular characteristics of human disease.Therefore,it is important that the researchers choose the appropriate animal model.This review discusses various genetically modified animal models developed and used in research on NAFLD.Perumal Nagarajan M Jerald Mahesh Kuma Ramasamy Venkatesan Subeer S Majundar Ramesh C Juyal M Jerald Mahesh Kuma 2012World Journal of Gastroenterology2012,18,11:7
2Biochem显示文摘Gupta SK Majundar S Bhattacharya TK Ghosh TC.Studies on the relationships between the synonymous codon usage and protein secondary structural units 0,,03:1
3Characterization and fnnctionality of cell surface molecules on human mesenchymal stem cells显示文摘Majundar MK Keane-Moorc M Buyaner D 2003J Biomed Sci2003,10,2:1
4Pilot-scale demonstration of a membrane-based absorption-stripping process for removal and recovery of volatile organic compounds显示文摘Majundar S Bhaumik D Sirkar K 2001Environment Progress2001,20,1:1
5Characterization and functionality of cell surface molecules on human mesenchymal stem cells显示文摘Majundar WK Keane-Moore M Buyaner D 2003J Biomed Sci2003,10,:1
6Phenotypic and functional comparison of cultures of marrow-derived mesenchymal stem cells(MSCs)and stromal cells显示文摘MAJUNDAR M K THIEDE M A MOSCA J D 1998J Cell Physiol1998,176,1:1
7Epidermal growth factor receptor-related protein inhibits cell growth and induces apoptosis of BxPC3 pancreatic cancer cells显示文摘Zhang Y Banerjee S Wang ZW Marchiniak DJ Majundar AP Sarkar FH 2005Cancer Res2005,65,9:1
8Properties of ring spun yarn made from cotton and regenerated bamboo fibers显示文摘ABHIJIT Majundar SAMRAT Mukhopadhyay RAVINDARA Yadav 2011Indian Journal of Fibre and Textile Research2011,36,:1
9Note on controlling a chaotic tournament显示文摘Bala V Majundar M A 2001Journal of Economic Behavior and Organization2001,12,5:1
10Fractal model of elastic-plastic contact between rough surfaces显示文摘Majundar A Bhushan B B 1991ASME Journal of Tribology1991,13,:1
11Prospects and future applications for diode lasers in surface engineering显示文摘Majundar J D 2007Surface Engineering2007,23,2:1
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