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109篇 您的检索式：作者名="Malemud"

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	题名	作者	年代	出处	被引量
1	Protein kinase small molecule inhibitors for rheumatoid arthritis: Medicinal chemistry/clinical perspectives显示文摘Medicinal chemistry strategies have contributed to the development, experimental study of and clinical trials assessment of the first type of protein kinase small molecule inhibitor to target the Janus kinase/Signal Transducers and Activators of Transcription(JAK/STAT) signaling pathway. The orally administered small molecule inhibitor, tofacitinib, is the first drug to target the JAK/STAT pathway for entry into the armamentarium of the medical therapy of rheumatoid arthritis. The introduction of tofacitinib into general rheumatologic practice coupled with increasing understanding that additional cellular signal transduction pathways including the mitogen-activated protein kinase and phosphatidylinositide-3-kinase/Akt/mammalian target of rapa-mycin pathways as well as spleen tyrosine kinase also contribute to immune-mediated inflammatory in rheumatoid arthritis makes it likely that further development of orally administered protein kinase small molecule inhibitors for rheumatoid arthritis will occur in the near future.	Charles J Malemud David E Blumenthal	2014	World Journal of Orthopedics2014，5，4：	5
2	Gene therapy for arthritis: defining novel gene targets显示文摘	Malemud CJ	2007	Gene Ther Mol Biol2007，11，：	1
3	Matrix metallop roteinases (MMPs) in health and disease : art overview 显示文摘	Malemud CJ	2006	From Biosci2006，11，1：	1
4	Pathophysiological mechanisms in osteoarthritis lead to novel therapeutic strategies 显示文摘	Malemud C J Islam N Haqqi TM	2003	Cells Tissues Or- gans2003，174，12：	1
5	Pathophysiologteal mechanisms in osteoarthritis lead to novel therapeutic strategies显示文摘	Malemud C J Islam N Haqqi TM	2003	Cells Tis- sues Organs2003，174，12：	1
6	Epigallocatechin-3-gallate selectively inhibits interleukin-1β-induced activation of mitogen activated protein kinase subgroup c-Jun N-terminal kinase in human osteoarthritis chondrocytes显示文摘	Singh R Ahmed S Malemud CJ	2003	J Orthop Res2003，21，1：	1
7	Matrix metalloproteinases (MMPS) in health and dis- ease:an overview 显示文摘	Malemud CJ	2006	Front Biosci2006，11，5：	1
8	Pathophysiological mechanisms in osteoarthritis lead to novel therapeutic strategies显示文摘	Malemud C J Islam N Haqqi TM	2003	Cells Tissues Or- gans2003，174，12：	1
9	Prospects for treating osteoa- rthritis: enzyme-protein interactions regulating matrix metallo- proteinase activity 显示文摘	MESZAROS E MALEMUD CJ	2012	Ther Adv Chronic Dis2012，3，5：	1
10	Matrix metalloproteinases (MMPs) in health and disease : an overview 显示文摘	Malemud CJ	2006	Front Biosci2006，11，5：	1
11	Matrix metalloproteinases (MMPs) in health and disease: an overview显示文摘	Malemud CJ	2006	Front Biosci2006，11，1：	1
12	Pathophysiological mechanisms in osteoarthritis lead to novel therapeutic strategies显示文摘	Malemud C J Islam N Haqqi TM	2003	Cells Tissues Or- galas2003，174，12：	1
13	Matrix metalloproteinases ( MMPs ) in health and disease:an overview 显示文摘	MALEMUD C J	2006	Frontiers in Bioscience: A Joumal and Virtual Library2006，11，：	1
14	Matrix metalloproteinases (MMPs) in health and disease:an overview显示文摘	Malemud CJ	2006	Front Biosci2006，11，1：	1
15	Age-related Changes in Serum Growth Hormone Insulin-like Growth Factor-1 and Somatostatin in System Lupus Erythematosus显示文摘	Denko CW Malemud CJ		0，，01：	1
16	Future direction for research and treatment of osteoarthritis显示文摘	Malemud C Goldberg V	1999	Front Biosci1999，4，：	1
17	Prospects for treating osteoarthritis: enzyme-protein inter-actions regulating matrix metalloproteinase anticity显示文摘	Meszaros E Malemud CJ	2012	Tner Adv Chronic Dis2012，3，5：	1
18	Protein kinases in chondrocyte signaling and osteoarthritis显示文摘	Malemud CJ	2004	Clin Orthop Relat Res2004，427，：	1
19	Anticytokine therapy for osteoarthritis: evidence to date 显示文摘	Malemud CJ	2010	Drugs Aging2010，27，：	1
20	Cardiovascular disease complications in systemic lupus erythematosus显示文摘	Tones A Askari AD Malemud CJ	2009	Biomark Med2009，3，：	1

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