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| 1 | Nonsurgical periodontal-therapy improves glycosylated hemoglobin levels in pre-diabetic patients with chronic periodontitis显示文摘AIM To evaluate the effect of nonsurgical periodontal therapy on glycosylated haemoglobin levels in pre-diabetic patients with chronic periodontitis(CHP).METHODS Sixty pre-diabetic patients with CHP were selected and equally allocated to case and control group. All subjects were evaluated at base line for periodontal parameters(plaque index, oral hygiene index, modified gingival index, probing pocket depth, clinical attachment level) and systemic parameters [glycosylated hemoglobin(HbA1c), fasting lipid profile, and fasting blood glucose]. The case group received non-surgical periodontal therapy. Subjects were re-evaluated for periodontal and systemic parameters after three months.RESULTS Both groups were comparable at baseline. Three months after non surgical periodontal therapy(NSPT), there was significant improvement in periodontal parameters in case group. The mean difference in systemic parameters like HbA1c and fasting plasma glucose from baseline to fourth month for case group was 0.22 ± 0.11 and 3.90 ± 8.48 respectively and control group was-0.056 ± 0.10 and-1.66 ± 6.04 respectively, which was significant between case and control group(P < 0.05). In the case group there was a significant decrease in HbA1c from baseline to three months following NSPT(P < 0.05).CONCLUSION This study showed that periodontal inflammation could affect the glycemic control in otherwise systemically healthy individuals. Periodontal therapy improved periodontal health status and decreased glycosylated haemoglobin levels, thus reducing the probability of occurrence of inflammation induced prediabetes in patients with CHP. | Rosamma Joseph Meera Sasikumar Jerry Mammen M G Joseraj Chandni Radhakrishnan | 2017 | World Journal of Diabetes2017，8，5： | 7 |
| 2 | Alpha-2 adrenergic receptor activation by brimonidine reduces neuronal apoptosis by inducing new protein synthesis that maintains mitochondrial pore closure显示文摘 | Chalmers-Redman RME Elstner MQ Mammen M | 2000 | Exp Eye Res2000，71，： | 2 |
| 3 | A Rare Presentation of Subacute Progressive Ascending Myelopathy Secondary to Cement Leakage in Percutaneous Vertebroplasty显示文摘 | Rohit Prakash Bhide Apurba Barman Shiela Mary Varghese Ahana Chatterjee Suraj Mammen Jacob George Raji Thomas | 2014 | American Journal of Physical Medicine & Rehabilitation2014，，5： | 2 |
| 4 | Bryostatin-1 enhances barrier function in T84 epithelia through PKC-dependent regulation of tight junction proteins显示文摘 | Yoo J Nichols A Mammen J | 2003 | Am J Physiol Cell Physiol2003，285，2： | 1 |
| 5 | Disseminated intravascular coagulation ( DIC ) 显示文摘 | Mammen EF | 2000 | Clin Lab Sci2000，13，4： | 1 |
| 6 | Optically controlled collisions of biological objects to evaluate potent polyvalent inhibitors of virus-cell adhesion显示文摘 | Mammen M Helmerson K Kishore R | 1996 | Chem Biol1996，3，： | 1 |
| 7 | Antithrombin:its physiological importance and role in DIC显示文摘 | Mammen EF | 1998 | Semin thromb Hemost1998，24，1： | 1 |
| 8 | The haematological manifestation of sepsis 显示文摘 | Mammen F | 1998 | Antimicrob Chemother1998，41，： | 1 |
| 9 | Clinical differentiation of low molecular weight heparins显示文摘 | Mammen E Arcelus J Messmore H | 1999 | Semin Thromb Hemost1999，25，3： | 1 |
| 10 | Myocyte-enriched calcineurin-interacting protein,MCIPI,inhibits cardiac hypertrophy in vivo显示文摘 | Rothermel BA McKinsey TA Vega RB Nieol RL Mammen P Yang J Antos CL Shelton JM Bassel-Duby R Olson EN Williams RS | 2001 | Proo Nail Aead Sei U S A2001，98，6： | 1 |
| 11 | Disseminated intravascular coagulation (DIC) 显示文摘 | | 2000 | Clin Lab Sci2000，13，4： | 1 |
| 12 | Evaluating electrostatic contributions to bindingwith the use of protein charge ladders 显示文摘 | Gao JM Mammen M Whitesides GM | 1996 | Science1996，272，5261： | 1 |
| 13 | Urapidil a review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in the treatment of hypertension显示文摘 | Langtry HD Mammen GJ Sorkin EM | 1989 | Drugs1989，38，： | 1 |
| 14 | Long-term risk of CKD in children surviving episodes of acute kidney injury in the intensive care unit:a prospective cohort study显示文摘 | Mammen C A1 Abbas A Skippen P | 2012 | Am J Kidney Dis2012，59，： | 1 |
| 15 | Locally Adaptive Regression Splines显示文摘 | Mammen E Geer S V D | 1997 | The Annals of Statistics1997，25，1： | 1 |
| 16 | Sepsisupregulates the gene expression of multiple ubiquitin li- gases in skeletal muscle显示文摘 | Wray C J Mammen J M Hershko D D | 2003 | Int J Biochem Cell Biol2003，35，5： | 1 |
| 17 | Characteristics of pa- tients with histories of multiple seclusion and restraint events during a single psychiatric hospitalization显示文摘 | Taylor K Mammen K Barnett S | 2012 | J Am Psychiatr Nurses Assoc2012，18，3： | 1 |
| 18 | Platelet function, thrombin and fibrinolytie activity in patents with heart failure显示文摘 | Jaffi SM Ozawz T Mammen E | 1993 | Eur Heart J1993，14，2： | 1 |
| 19 | Disseminated intravaseular coagulation ( DIC ) 显示文摘 | Mammen EF | 2000 | Clin Lab Sci2000，13，： | 1 |
| 20 | Comparing Nonparametric Versus Parametric Regression Fits显示文摘 | Hardle W Mammen E | 1993 | The Annals of Statistics1993，，4： | 1 |
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