|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Novel biomarkers for patient stratification in colorectal cancer:A review of definitions,emerging concepts,and data显示文摘Colorectal cancer(CRC) treatment has become more personalised,incorporating a combination of the individual patient risk assessment,gene testing,and chemotherapy with surgery for optimal care.The improvement of staging with high-resolution imaging has allowed more selective treatments,optimising survival outcomes.The next step is to identify biomarkers that can inform clinicians of expected prognosis and offer the most beneficial treatment,while reducing unnecessary morbidity for the patient.The search for biomarkers in CRC has been of significant interest,with questions remaining on their impact and applicability.The study of biomarkers can be broadly divided into metabolic,molecular,micro RNA,epithelial-to-mesenchymal-transition(EMT),and imaging classes.Although numerous molecules have claimed to impact prognosis and treatment,their clinical application has been limited.Furthermore,routine testing of prognostic markers with no demonstrable influence on response to treatment is a questionable practice,as it increases cost and can adversely affect expectations of treatment.In this review we focus on recent developments and emerging biomarkers with potential utility for clinical translation in CRC.We examine and critically appraise novel imaging and molecular-based approaches; evaluate the promising array of micro RNAs,analyze metabolic profiles,and highlight key findings for biomarker potential in the EMT pathway. | Manish Chand Deborah S Keller Reza Mirnezami Marc Bullock Aneel Bhangu Brendan Moran Paris P Tekkis Gina Brown Alex Mirnezami Mariana Berho | 2018 | World Journal of Gastrointestinal Oncology2018，10，7： | 2 |
| 2 | Fuzzy-rough Nearest Neighbor Algorithms in Classification 显示文摘 | Manish S | 2007 | Fuzzy Sets and Systems2007，158，19： | 1 |
| 3 | Classification of power quality events: A review显示文摘 | Manish K S Rajiv K | 2012 | Electrical Power and Energy Systems2012，43，： | 1 |
| 4 | Shift dynamics and control of dual- clutch transmissions 显示文摘 | MANISH K TAEHYUN S YI Z | 2007 | Mechanism and Machine Theory2007，42，2： | 1 |
| 5 | Multivariate process monitoring and fault diagnosis by multi-scale PCA显示文摘 | Manish M Henry Joe Q S | 2002 | Computers and Chemical Engineering2002，26，9： | 1 |
| 6 | Arene ruthenium complexes incorporating immine/azine hybrid-chelating N- N' donor ligands: Synthetic, spectral, structural aspects and DFT studies 显示文摘 | Manish C Abhaya N Sahay | 2004 | Journal of Organometallic Chemistry2004，689，： | 1 |
| 7 | Moderate Treadmill Exercise Prevents Oxidative Stress-Induced Anxiety-Like Behavior In Rats 显示文摘 | SAMINA S NADA S MANISH T | 2010 | Behavioural Brain Research2010，208，： | 1 |
| 8 | Optimalservicepricingforcloudbasedservicas显示文摘 | DEEPAKM MANISH S | 2012 | InternationalJournalofSoftComputingandEngineering2012，3，2： | 1 |
| 9 | Aggressive approach to staghorn calculi-safety and efficacy of multiple tracts percutaneous nephrolithotomy显示文摘 | MANISH S ANEESH S RAKESH K | 2008 | Urology2008，71，6： | 1 |
| 10 | Molecular Synthesis of Polymer-Trapped Silica and Titania Nanoclustres显示文摘 | Manish N Jeanine A Ayusman S | 1991 | Chemistry of Materials1991，3，1： | 1 |
| 11 | High temperature C/C-SiC composite by liquid silicon infiltration显示文摘 | MANISH P KUMAR S | 2012 | Bulletin of Materials Science2012，35，1： | 1 |
| 12 | Multivariate Process Monitoring and Fault Diagnosis by Multi-scale PCA显示文摘 | Manish M Henry Joe Q S | | 0，，09： | 1 |
| 13 | Hydrophobic properties of TMOS/ TMES based silica areogels 显示文摘 | RAO A V MANISH S K | 2002 | Materials Research Bulletin2002，37，： | 1 |
| 14 | Seismic damage detection in building frame via finite element model updating显示文摘 | Shiradhonkar S R Manish Shrikhande | 2011 | Computers and Structures2011，89，： | 1 |
| 15 | Moderate Treadmill Exercise ?revents Oxidative Stress-Induced Anxiety-Like Behavior In Rats 显示文摘 | SAMINA S NADA S MANISH T | 2010 | ehavioural Brain Research2010，208，： | 1 |
| 16 | Aggressive approach to staghorn calculi-safety and efficacy of multiple tracts percutaneous nephrolithotomy显示文摘 | Manish S Aneesh S Rakesh K | 2008 | Urol2008，71，6： | 1 |
| 17 | Dependability modeling using Petri-nets 显示文摘 | Manish Mallhotra Kishor S Trivedi | 1995 | IEEE Transactions on Reliability (S0018-9529)1995，44，3： | 1 |
| 18 | Aggressive approach to staghorn calculi--safety and efficacy of multiple tracts percutaneous nephrolithotomy 显示文摘 | Manish S Aneesh S Rakesh K | 2008 | Urology2008，71，6： | 1 |
| 19 | Pro- spective Randomized Comparison of Retroperitoneo- scopic vs Open Pyeloplasty With Minimal Incision: Subjective and Objective Assessment in Adults显示文摘 | Manish G Vishwajeet S Rahul Janak S | 2014 | U- rology2014，83，4： | 1 |
| 20 | Analysis of flow through an orifice meter:CFD simulation显示文摘 | MANISH S JYESHTHARAJ S JOSHI B | 2013 | Chemical Engineering Science2013，，71： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员