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| 1 | 非胰岛素依赖型糖尿病冠状动脉疾病的危险因素:英国糖尿病前瞻性研究(UKPDS:23)显示文摘目的:评价2型糖尿病患者冠状动脉疾病的基线危险因素。设计:对2 693例资料完整的患者进行年龄和性别调整的逐步选择过程分析,以确定哪些冠状动脉疾病的危险因素应纳入 Cox 比例风险模型。对象:3 055例白人患者,平均年龄52岁,均新近诊断为2型糖尿病,且无动脉粥样硬化相关疾病的证据。平均随访期7.9年。335例患者于10年内出现冠状动脉疾病。结局评定:具有明确异常心电图的心绞痛、致死或非致死性心肌梗塞。结果:冠状动脉疾病与低密度脂蛋白胆固醇浓度升高、高密度脂蛋白胆固醇浓度降低、甘油三酯浓度升高、高血红蛋白 A_(1c)、高收缩压、高空腹血糖以及吸烟史密切相关。低密度脂蛋白胆固醇较高1/3对较低1/3区间的估计风险比为2.26(95%可信区间为1.70~3.00),高密度脂蛋白胆固醇为0.55(0.41~0.73),血红蛋白 A_(1c)为1.52(1.15~2.01),收缩压为1.82(1.34~2.47)。吸烟者的估计风险比为1.41(1.06~1.88)。结论:2型糖尿病患者中,存在冠状动脉疾病潜在的、可变的5种危险因素的交叉重叠影响。它们是低密度脂蛋白胆固醇浓度升高、高密度脂蛋白胆固醇浓度降低、高血压、高血糖和吸烟。 | R C Turner H Millns H A W Neil I M Stratton S E Manley D R Matthews R R Holman 赵维纲 | 1998 | 英国医学杂志中文版1998，0，3： | 11 |
| 2 | New experience with alumi- na - on - alumina ceramic bearing for total hip arthroplasty 显示文摘 | D' Antonio J Capello W Manley M | 2002 | J Arthroplasty2002，17，： | 1 |
| 3 | The basis for a second-generation highly cross-linked UHMWPE显示文摘 | Dumbleton JH D' Antonio JA Manley MT | 2006 | Clin Orthop Relat Res2006，45，3： | 1 |
| 4 | Greatly impaired migration of implanted aquapor in-4-deficient astroglial cells in mouse brain toward a site of in jury显示文摘 | Auguste K I Jin S Uchida K Yan D Manley G T Papadopou los M C etal | 2007 | FASEB J2007，21，： | 1 |
| 5 | Hypotension,hypoxia,and head injury:frequency,duration,and consequences显示文摘 | Manley G Knudson MM Morabito D | | 0，，： | 1 |
| 6 | Ontology-based assembly design and information sharing for collaborative product development显示文摘 | KIM K Y MANLEY D G YANG H | 2006 | Computer- Aided Design2006，38，12： | 1 |
| 7 | Vapor-liquid equilibrium data for the NH3-H2O system and its description with a modified cubic equation of state显示文摘 | Smolen T M Manley D B Poling B E | 1991 | J Chem Eng Data1991，36，2： | 1 |
| 8 | Amino acid sequence of ghilanten:anticoagulant-antimetastatic principle of the South American leech,Haementeria ghilianii显示文摘 | Blankenship D T Brankamp R G Manley G D | 1990 | Biochem Biophys Res Commun1990，166，3： | 1 |
| 9 | Impact of grazing management on the carbon and nitrogen balance of a mixed-grass rangeland显示文摘 | Schuman G E Reeder J D Manley J T | 1999 | Ecological Applications1999，9，1： | 1 |
| 10 | New experience with alumina-on-alumina ceramic bearings for total hip arthroplasty显示文摘 | Capello W Manley M | 2002 | J Arthroplasty2002，17，4： | 1 |
| 11 | A survey of energy policy priorities in the United States: energy supply security, economics, and the environment 显示文摘 | Manley D K Hines V A Jordan M W | 2013 | Energy Policy2013，60，9： | 1 |
| 12 | New experience with alumina-on-alumina ceramic bearings for total hip arthroplasty 显示文摘 | Capello W Manley M | 2002 | J Arthroplasty2002，17，4： | 1 |
| 13 | Ontology-based assembly design and information sharing for collaborative product development 显示文摘 | Kim K Manley D Yang H | 2006 | Computer- Aided Design2006，38，12： | 1 |
| 14 | Synthetic polymer-lignin copolymers and blend显示文摘 | WANG J S MANLEY R S FELDMAN D | 1992 | Prog Polym Sci1992，17，： | 1 |
| 15 | Solvent-free bonding of shoe-soling materials显示文摘 | ABBOTT S G BREWIS D M MANLEY N E | 2003 | International Journal of Adhesion and Adhesives2003，23，： | 1 |
| 16 | Morphology of abyssal mudwaves at Project MUDWAVES sites in the Argentine Basin显示文摘 | Flood R D Shor A N Manley P D | 1993 | Deep-Sea Research1993，40，： | 1 |
| 17 | Interleukin 10 extends the effectiveness of standard therapy during late sepsis with serum interleukin 6 levels predicting outcome显示文摘 | Manley M O O'Riordan M A Levine A D etal | 2005 | Shock2005，23，6： | 1 |
| 18 | Ontology based assembly design and information sharing for collaborative product development 显示文摘 | Kim K Y Manley D G Yang H | 2006 | Computer-Aided Design2006，38，12： | 1 |
| 19 | Ontology-based assembly design and information sharing for collaborative product development显示文摘 | KIM K Y MANLEY D G YANG H J | 2006 | Computer-Aided Design2006，38，12： | 1 |
| 20 | Impactof grazing managerment on the cabon and mitrogen bal-ance of a mixed-grass rangeland显示文摘 | Schuman G E Reader J D Manley J T | 1999 | Ecological applaca-tions1999，9，1： | 1 |
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