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| 1 | Effect of intra-abdominal pressure on respiratory function in patients undergoing ventral hernia repair显示文摘AIM: To determine the influence of intra-abdominal pressure(IAP) on respiratory function after surgical repair of ventral hernia and to compare two different methods of IAP measurement during the perioperative period. METHODS: Thirty adult patients after elective repair of ventral hernia were enrolled into this prospective study.IAP monitoring was performed via both a balloontipped nasogastric probe [intragastric pressure(IGP), Ci MON, Pulsion Medical Systems, Munich, Germany] and a urinary catheter [intrabladder pressure(IBP), Uno Meter Abdo-Pressure Kit, Uno Medical, Denmark] on five consecutive stages:(1) after tracheal intubation(AI);(2) after ventral hernia repair;(3) at the end of surgery;(4) during spontaneous breathing trial through the endotracheal tube; and(5) at 1 h after tracheal extubation. The patients were in the complete supine position during all study stages.RESULTS: The IAP(measured via both techniques) increased on average by 12% during surgery compared to AI(P < 0.02) and by 43% during spontaneous breathing through the endotracheal tube(P < 0.01). In parallel, the gradient between РаСО2 and Et CO2 [Р(а-et)CO2] rose significantly, reaching a maximum during the spontaneous breathing trial. The PаO2/Fi O2 decreased by 30% one hour after tracheal extubation(P = 0.02). The dynamic compliance of respiratory system reduced intraoperatively by 15%-20%(P < 0.025). At all stages, we observed a significant correlation between IGP and IBP(r = 0.65-0.81, P < 0.01) with a mean bias varying from-0.19 mm Hg(2SD 7.25 mm Hg) to-1.06 mm Hg(2SD 8.04 mm Hg) depending on the study stage. Taking all paired measurements together(n = 133), the median IGP was 8.0(5.5-11.0) mm Hg and the median IBP was 8.8(5.8-13.1) mm Hg. The overall r2 value( n = 30) was 0.76(P < 0.0001). Bland and Altman analysis showed an overall bias for the mean values per patient of 0.6 mm Hg(2SD 4.2 mm Hg) with percentage error of 45.6%. Looking at changes in IAP between the different study stages, we found an excellent concordance coefficient of 94.9% comparing IBP and IGP( n = 117).CONCLUSION: During ventral hernia repair, the IAP rise is accompanied by changes in Р(а-et)CO2 and PаO2/Fi O2-ratio. Estimation of IAP via IGP or IBP demonstrated excellent concordance. | Konstantin M Gaidukov Elena N Raibuzhis Ayyaz Hussain Alexey Y Teterin Alexey A Smetkin Vsevolod V Kuzkov Manu LNG Malbrain Mikhail Y Kirov | 2013 | World Journal of Critical Care Medicine2013，2，2： | 2 |
| 2 | Innovation, Marketing Stratege, Environment and Performance 显示文摘 | Manu F A Sriram V | 1996 | Journal of Business Research1996，35，3： | 1 |
| 3 | Methods and concepts in quantifying resistance to drought,salt and freezing,abiotic stresses that affect plant water status显示文摘 | PAUL E V MANU A | 2006 | The Plant Journal2006，45，： | 1 |
| 4 | Effect of nickel-rich layer on improvement of hot-dip zinc coating 显示文摘 | Shibi S M A Manu R Dilimon V S | 2005 | Applied Surface Science2005，245，： | 1 |
| 5 | Effect of nickel- rich barrier layer on improvement of hot-dip zinc coat- ing显示文摘 | Shibli S M A Manu R Dilimon V S | 2005 | Applied Surface Science2005，245，14： | 1 |
| 6 | Effect of Nickel-rich Barrier Layer on Improvement of Hot-dip Zinc Coating显示文摘 | SHIBIS M A MANU R DILIMON V S | 2005 | Applied Surface Science2005，245，1： | 1 |
| 7 | Effect of nickel-rich layer on improvement of hot-dip zinc coating 显示文摘 | Shibi S M A Manu R Dilimon V S | 2005 | Appl Surf Sci2005，245，： | 1 |
| 8 | Effect of nickel-rich barrier layer on improvement of hot-dip zinc coating显示文摘 | Shibli S M A Manu R Dilimon V S | 2005 | Applied Surface Science2005，245，14： | 1 |
| 9 | A retrospective analysis of serial measurement of serum cholinesterase in acute poisoning with organophosphate compounds显示文摘 | Manu MS Prashant V Akila P | 2012 | Toxicol Int2012，19，3： | 1 |
| 10 | Effect of nickel-rich barrier layer on improvement of hot-dip zinc coating显示文摘 | Shibli S M A Manu R Dilimon V S | 2005 | Applied Surface Science2005，245，14： | 1 |
| 11 | Cardiometabolic risk of second-generation antipsychotic medications during first-time use in children and adolescents 显示文摘 | Correll CU Manu P Olshanskiy V | 2009 | JAMA2009，302，： | 1 |
| 12 | Kinetics of glycidyl azide polymer-based urethane network formation显示文摘 | MANU S K SEKKAR V SCARIAH K J | 2008 | J Appl Polym Sei2008，110，2： | 1 |
| 13 | Raised plasma adiponectin levels on lype 1 diabetic pregnaneies显示文摘 | Randeva HS Manu V Bee KT | 2006 | Clinical Endocrinology2006，65，： | 1 |
| 14 | Erythromycin lacks colon prokinetic effect in children with functional gastrointestinal disorders:a retrospective study显示文摘 | Narayanan V Colin DR Manu RS | 2008 | BMC Gastroenterology2008，38，1： | 1 |
| 15 | Cooling Techniques for Improved Productivity in Turning 显示文摘 | SHARMA V S MANU D SURI N M | 2009 | International Journal of Machine Tools & Manufacture2009，46，6： | 1 |
| 16 | Inactivity and inaction 显示文摘 | Manu V Chakravarthy Frank W Booth | 2003 | Arch Pediatr Adolesc Med2003，157，： | 1 |
| 17 | Raised plasma adiponectin levels on type 1 diabetic pregnancies显示文摘 | Randeva HS Manu V Bee KT | 2006 | Clinical Endocrinology2006，65，： | 1 |
| 18 | Innovation, marketing strate?gy, environment and performance显示文摘 | MANU F A SRIRAM V | 1996 | Journal of Business Research1996，35，： | 1 |
| 19 | Effects of Angiotensin Ⅱ on human endothelial cells survival signaling pathway and its angiogenic response显示文摘 | Kou BJ Manu V Donald RJ | 2007 | Vascular Pharmacology2007，47，4： | 1 |
| 20 | Intraparenchymal clear cell ependy-moma显示文摘 | Deb P Manu V Pradeep H Bhatoe HS | 2011 | J Cytol2011，28，2： | 1 |
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