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| 1 | High-Resolution Crystal Structure and Redox Properties of Chloroplastic Triosephosphate Isomerase from Chlamydomonas reinhardtii显示文摘Triosephosphate isomerase (TPI ) 催化 glyceraldehyde-3-phosphate 的互变现象到 dihydroxyacetone 磷酸盐。光合的有机体通常包含位于细胞质和叶绿体的 TPI 的二 isoforms。当细胞质的 TPI 涉及 glycolysis 时, chloroplastic isoform 参予 CalvinBenson 周期,为碳固定负责的一个关键光合的过程。与它的细胞质的对应物相比, chloroplastic TPI 的功能的特征糟糕被调查了,它的三维的结构没被解决。最近,几研究包括 dithiol/disulfide 交换, glutathionylation,和 nitrosylation 作为不同氧化还原作用修正的一个潜在的目标建议了 TPI。然而,在蛋白质活动的既不效果也不位于这些氧化还原作用修正下面的分子的机制被调查了。这里,我们 recombinantly 生产了并且从单细胞的绿水藻 Chlamydomonas reinhardtii (Cr ) 净化了 TPI。酶的生物化学的性质被描出,它的结晶的结构在 1.1 的一个决定是坚定的 ? 。CrTPI 是有包含典型(/)8 桶褶层的子单元的 homodimer。尽管为 TRX 规定的证据都没被获得, CrTPI 被发现由 nitrosoglutathione 由氧化谷胱甘肽和 trans-nitrosylation 经历 glutathionylation,证实它到多重氧化还原作用修正的敏感。 | Mirko Zaffagnini Laure Michelet Chiara Sciabolini Nastasia Di Giacinto Samuel Morisse Christophe H. Marchand Paolo Trost Simona Fermani Stephane D Lemaire | 2014 | Molecular Plant2014，7，1： | 4 |
| 2 | Evidence for an involvement of supra-spinal δ- and spinal μ-opioid receptors in the antihyperalgesic effect of chronically administred clomipramine in mononeuropathic rats显示文摘 | MARCHAND F ARDID D CHAPUY E | 2003 | J Pharmacol Exp Ther2003，307，1： | 1 |
| 3 | Qualitative aspects of nasal irrigation use by patients with chronic sinus disease in a muhimethod study显示文摘 | Rabago D Barrett B Marchand L | 2006 | Ann Fam Med2006，4，4： | 1 |
| 4 | Influence of fish density on the energy allocation pattern of juvenile brook trout (Salvelinus fontinalis)显示文摘 | Marchand F Boisclair D | 1998 | Can J Fish Aquat Sci1998，55，： | 1 |
| 5 | Qualitative aspects of nasal irrigation use by patients with chronic sinus disease in a multimethod study显示文摘 | Rabago D Barrett B Marchand L | 2006 | Ann Fam Med2006，4，4： | 1 |
| 6 | Analy- sis and design of critical bridges subjected to blast loads 显示文摘 | WINGET D G MARCHAND K A WILLIAMSON E B | 2005 | ASCE Journal of Structural Engineering2005，131，8： | 1 |
| 7 | Photonic polyethylene from self-assembled mesophases of polydisperse olefin block copolymers显示文摘 | Hustad P D Marchand G R Eddy I | | 0，，： | 1 |
| 8 | Expression of the RND-type efflux pump AdeABC in Acinetobacter baumannii is regulated by the AdeRS two-component system 显示文摘 | Marchand I Piolle D L Courvalin P | 2004 | Antimicrob Agents Chemother2004，48，8： | 1 |
| 9 | DMRT1 expression during gonadal differentiation and spermatogenesis in the rainbow trout,Oncorhynchus mykiss显示文摘 | Govoroun M D′ Cotta H | 2000 | Biochimica et Biophysica Acta2000，1493，： | 1 |
| 10 | The Stabilization of the Salicylaldehydeglycine Schif Base Though Metal Complex Formation 显示文摘 | Eichhorn G L Marchand N D | 1956 | J Am Chem Soc1956，12，78： | 1 |
| 11 | Synthesis of (Z) - and (E) -1,2-di ( 1 -adamantyl ) ethene and their respective reactions with dichlorocarbenel 显示文摘 | MARCHAND A P XING D BOTTS | 1996 | Tetrahedron1996，52，3： | 1 |
| 12 | Information orientation:People,technology and the bottom line显示文摘 | MARCHAND D A KETTINGER W J ROLLINS J D | 2000 | Sloan Management Review2000，，4： | 1 |
| 13 | Influence of fish density on the energy allocation pattern of juvenile brook trout( Salvelinus fontinalis ) 显示文摘 | MARCHAND F BOISCLAIR D | 1998 | Can J Fish1998，55，4： | 1 |
| 14 | La dechloration par condensation: une technique promerreuse 显示文摘 | Grand D Marchand D | 1991 | Environment & Technique1991，16，3： | 1 |
| 15 | Electrophysiological assessment of language function following stroke 显示文摘 | D' Arcy RN Marchand Y Eskes GA | 2003 | Clin Neurophysiol2003，114，4： | 1 |
| 16 | Information orientation: people, technology and the bottom line显示文摘 | Marchand D A Kettinger W J Rollins J D | 2000 | Sloan Management Review2000，41，4： | 1 |
| 17 | TG1050,an immunotherapeutic to treat chronic hepatitis B,induces robust T cells and exerts an antiviral effect in HBVpersistent mice显示文摘 | Martin P Dubois C Jacquier E Dion S ManciniBourgine M Godon O Kratzer R Lelu-Santolaria K Evlachev A Meritet J F Schlesinger Y Villeval D Strub J M Van Dorsselaer A Marchand J B Geist M Brandely R Findeli A Boukhebza H Menguy T Silvestre N Michel M L InchauspéG | 2015 | Gut2015，64，12： | 1 |
| 18 | Qualitative aspects of nasal irrigation use by patients with chronic sinus disease in a multimethod study显示文摘 | Rabago D Barrett B Marchand L | 2006 | Ann Family Med2006，4，4： | 1 |
| 19 | Delivery of antisense oligonucleotides using cholesterol-modified sense dendrimers and cationic lipids显示文摘 | Chaltin P Margineanu A Marchand D | 2005 | Bioconjug Chem2005，16，4： | 1 |
| 20 | DMRTI expression during gonadal differentiation and sperrnatogenesis in the rainbow trout, Oncorhynchus mykiss 显示文摘 | Marchand O Govoroun M D' Cotta H | 2000 | Biochim Biophys Acta2000，1493，： | 1 |
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