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| 1 | Operative link for gastritis assessment vs operative link on intestinal metaplasia assessment显示文摘AIM:To compare the reliability of gastritis staging sys-tems in ranking gastritis-associated cancer risk in a large series of consecutive patients.METHODS:Gastric mucosal atrophy is the precancer-ous condition in which intestinal-type gastric cancer(GC)most frequently develops.The operative link for gas-tritis assessment(OLGA)staging system ranks the GC risk according to both the topography and the severity of gastric atrophy(as assessed histologically on the ba-sis of the Sydney protocol for gastric mucosal biopsy).Both cross-sectional and long-term follow-up trials have consistently associated OLGA stages Ⅲ-Ⅳ with a higher risk of GC.A recently-proposed modification of the OLGA staging system(OLGIM)basically incorporates the OLGA frame,but replaces the atrophy score with an assessment of intestinal metaplasia(IM)alone.A series of 4552 consecutive biopsy sets(2007-2009)was re-trieved and reassessed according to both the OLGA and the OLGIM staging systems.A set of at least 5 biopsy samples was available for all the cases considered.RESULTS:In 4460 of 4552 cases(98.0%),both the high-risk stages(Ⅲ + Ⅳ)and the low-risk stages(0 +Ⅰ + Ⅱ)were assessed applying the OLGA and OL-GIM criteria.Among the 243 OLGA high-risk stages,14(5.8%)were down-staged to a low risk using OLGIM.The 67(1.5%)incidentally-found neoplastic lesions(intraepithelial or invasive)were consistently associated with high-risk stages,as assessed by both OLGA and OLGIM(P < 0.001 for both).Two of 34 intestinal-type GCs coexisting with a high-risk OLGA stage(stage Ⅲ)were associated with a low-risk OLGIM stage(stage Ⅱ).CONCLUSION:Gastritis staging systems(both OLGA and OLGIM)convey prognostically important informa-tion on the gastritis-associated cancer risk.Because of its clinical impact,the stage of gastritis should be included as a conclusive message in the gastritis histol-ogy report.Since it focuses on IM alone,OLGIM staging is less sensitive than OLGA staging in the identif ication of patients at high risk of gastric cancer. | Massimo Rugge Matteo Fassan Marco Pizzi Fabio Farinati Giacomo Carlo Sturniolo Mario Plebani David Y Graham | 2011 | World Journal of Gastroenterology2011，17，41： | 19 |
| 2 | PDCD4/miR-21 dysregulation in inflammatory bowel disease-associated carcinogenesis显示文摘 | Kathrin Ludwig Matteo Fassan Claudia Mescoli Marco Pizzi Mariangela Balistreri Laura Albertoni Salvatore Pucciarelli Marco Scarpa Giacomo Carlo Sturniolo Imerio Angriman Massimo Rugge | 2013 | Virchows Archiv2013，，1： | 3 |
| 3 | HER2 status in gastroesophageal cancer: a tissue microarray study of 1040 cases显示文摘 | Rocco Cappellesso Matteo Fassan Esther Hanspeter Jan Bornschein Emanuele S.G. d’Amore Lucia V. Cuorvo Guido Mazzoleni Mattia Barbareschi Marco Pizzi Vincenza Guzzardo Peter Malfertheiner Marjan Micev Maria Guido Luciano Giacomelli Vladislav V. Tsukanov Vi | 2015 | Human Pathology2015，，5： | 1 |
| 4 | Human epithelial growth factor receptor 2 (HER2) status in primary and metastatic esophagogastric junction adenocarcinomas显示文摘 | Matteo Fassan Kathrin Ludwig Marco Pizzi Carlo Castoro Vincenza Guzzardo Mariangela Balistreri Giovanni Zaninotto Alberto Ruol Luciano Giacomelli Ermanno Ancona Massimo Rugge | 2012 | Human Pathology2012，，8： | 1 |
| 5 | The HER2-miR125a5p/miR125b loop in gastric and esophageal carcinogenesis显示文摘 | Matteo Fassan Marco Pizzi Stefano Realdon Mariangela Balistreri Vincenza Guzzardo Vittorina Zagonel Carlo Castoro Luca Mastracci Fabio Farinati Donato Nitti Giovanni Zaninotto Massimo Rugge | 2013 | Human Pathology2013，，9： | 1 |
| 6 | Enhancing multi-hop communication over multi-radio multi-channel wireless mesh networks: A cross-layer approach显示文摘 | Luciano Bononi Marco Di Felice Antonella Molinaro Sara Pizzi | 2010 | Computer Communications2010，，13： | 1 |
| 7 | PDCD4/miR-21 dysregulation in inflammatory bowel disease-associated carcinogenesis显示文摘 | Kathrin Ludwig Matteo Fassan Claudia Mescoli Marco Pizzi Mariangela Balistreri Laura Albertoni Salvatore Pucciarelli Marco Scarpa Giacomo Carlo Sturniolo Imerio Angriman Massimo Rugge | 2013 | Virchows Archiv2013，，1： | 1 |
| 8 | Plasma small-extracellular vesicles enriched in miR-122-5p promote disease aggressiveness in pediatric anaplastic large-cell lymphoma显示文摘Dear Editor,Anaplastic lymphoma kinase-positive(ALK+)anaplastic large cell lymphoma(ALCL)is an aggressive peripheral Tcell lymphoma representing 10%-15%of pediatric lymphoid neoplasms.The constitutively activated nucleophosmin-ALK(NPM-ALK)fusion protein is the main driver of ALK+ALCL oncogenesis[1].Current clinical protocols can achieve high cure rates,with 75%event-free survival(EFS)at 5 years[2],but the patients’outcome with relapsed/refractory disease still remains poor[3].Liquid biopsy is widely applied for the prognostic and therapeutic stratification of onco-hematological patients.As a non-invasive procedure,it can be used to identify several biomarkers,such as small extracellular vesicles(S-EVs)[4].S-EVs are stable carriers of molecules that mediate genetic exchange between distant cells,alter the microenvironment,facilitate cancer cell progression and promote drug resistance[5]. | Carlotta Caterina Damanti Lavinia Ferrone Enrico Gaffo Anna Garbin Anna Tosato Giorgia Contarini Ilaria Gallingani Roberta Angioni Barbara Molon Giulia Borile Elisa Carraro Marta Pillon Federico Scarmozzino Angelo Paolo Dei Tos Marco Pizzi Francesco Ciscato Andrea Rasola Alessandra Biffi Stefania Bortoluzzi Federica Lovisa Lara Mussolin | 2023 | Cancer Communications2023，43，5： | 0 |
| 9 | Nonlinear Diffusion and Transient Osmosis显示文摘We investigate both analytically and numerically the concentration dynamics of a solution in two containersconnected by a narrow and short channel,in which diffusion obeys a porous medium equation.We also considerthe variation of the pressure in the containers due to the How of matter in the channel.In particular,we identifya phenomenon,which depends on the transport of matter across nano-porous membranes,which we call 'transientosmosis'.We find that nonlinear diffusion of the porous medium equation type allows numerous different osmotic-likephenomena,which are not present in the case of ordinary Fickian diffusion.Experimental results suggest one possiblecandidate for transiently osmotic processes. | Akira Igarashi Lamberto Rondoni Antonio Botrugno Marco Pizzi | 2011 | Communications in Theoretical Physics2011，56，8： | 0 |
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