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6篇 您的检索式:作者名="Margalida"
    题名 作者 年代 出处 被引量
1Neuroprotective Effects of Estradiol on Motoneurons in a Model of Rat Spinal Cord Embryonic Explants显示文摘Andrea Cardona-Rossinyol Margalida Mir Víctor Caraballo-Miralles Jerònia Lladó Gabriel Olmos 2013Cellular and Molecular Neurobiology2013,,3:1
2In vivo analysis of efavirenz metabolism in individuals with impaired CYP2A6 function显示文摘Julia di Iulio Aurélie Fayet Mona Arab-Alameddine Margalida Rotger Rubin Lubomirov Matthias Cavassini Hansjakob Furrer Huldrych F. Günthard Sara Colombo Chantal Csajka Chin B. Eap Laurent A. Decosterd Amalio Telenti 2009Pharmacogenetics and Genomics2009,,4:1
3Bacterial PAH degradation in marine and terrestrial habitats显示文摘JOAQUIM V MARGALIDA T MAGDALENA G 2015Current Opinion in Biotechnology2015,33,1:1
4Insights into the role of major bioactive dietary nutrients in lamb meat quality:a review显示文摘Feed supplementation withα-linolenic acid(ALA)and linoleic acid(LA)increases their content in muscle,ALA increases n-3 polyunsaturated fatty acids and decrease n-6/n-3 ratio in muscle,and LA increases rumenic acid.However,high LA supplementation may have negative effects on lambs’lipid oxidative stability of meat.When the sources of ALA and LA are fed as fresh forage,the negative effects are counterbalanced by the presence of other bioactive compounds,as vitamin E(mainlyα-tocopherol)and polyphenols,which delay the lipid oxidation in meat.There is a wide consensus on the capability of vitamin E delaying lipid oxidation on lamb meat,and its feed content should be adjusted to the length of supplementation.A high dietary inclusion of proanthocyanidins,phenolic compounds and terpenes reduce the lipid oxidation in muscle and may improve the shelf life of meat,probably as a result of a combined effect with dietary vitamin E.However,the recommended dietary inclusion levels depend on the polyphenol type and concentration and antioxidant capacity of the feedstuffs,which cannot be compared easily because no routine analytical grading methods are yet available.Unless phenolic compounds content in dietary ingredients/supplements for lambs are reported,no specific association with animal physiology responses may be established.JavierÁlvarez-Rodríguez Olaia Urrutia Sandra Lobón Guillermo Ripoll Juan Ramón Bertolín Margalida Joy 2022Journal of Animal Science and Biotechnology2022,13,4:1
5筑巢前,请自由飞翔显示文摘作为一名拥有图书馆和信息科学学士学位的自由自然主义者,我度过了科学生涯的前17年。这很具有挑战性,我发现它在智慧上是有所回报的,我喜欢探索科学,而不需要面对那些追求学术生涯的实习生通常所要承受的压力和不确定性,我让创造力得以发展。然而7年前,当我参加一个关于胡兀鹫的会议时,我的职业生涯发生了转折,这让我在38岁时获得了博士学位。Antoni Margalida 倪伟波(译) 2018科学新闻2018,0,3:0
6Phylobone: a comprehensive database of bone extracellular matrix proteins in human and model organisms显示文摘The bone extracellular matrix(ECM) contains minerals deposited on highly crosslinked collagen fibrils and hundreds of noncollagenous proteins. Some of these proteins are key to the regulation of bone formation and regeneration via signaling pathways,and play important regulatory and structural roles. However, the complete list of bone extracellular matrix proteins, their roles, and the extent of individual and cross-species variations have not been fully captured in both humans and model organisms. Here, we introduce the most comprehensive resource of bone extracellular matrix(ECM) proteins that can be used in research fields such as bone regeneration, osteoporosis, and mechanobiology. The Phylobone database(available at https://phylobone.com) includes 255proteins potentially expressed in the bone extracellular matrix(ECM) of humans and 30 species of vertebrates. A bioinformatics pipeline was used to identify the evolutionary relationships of bone ECM proteins. The analysis facilitated the identification of potential model organisms to study the molecular mechanisms of bone regeneration. A network analysis showed high connectivity of bone ECM proteins. A total of 214 functional protein domains were identified, including collagen and the domains involved in bone formation and resorption. Information from public drug repositories was used to identify potential repurposing of existing drugs. The Phylobone database provides a platform to study bone regeneration and osteoporosis in light of(biological) evolution,and will substantially contribute to the identification of molecular mechanisms and drug targets.Margalida Fontcuberta-Rigo Miho Nakamura Pere Puigbò 2023Bone Research2023,11,3:0
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