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| 1 | “猪地方性肺炎及其防治控制”专栏二:有关猪肺炎支原体感染诊断方法和流行病学的最新观点显示文摘猪肺炎支原体是猪地方性肺炎(Enzoodc Pneumonia,EP)的主要病原体,本病是一种主要影响肥育猪的慢性呼吸道疾病。尽管人们在控制猪肺炎支原体感染及其带来的不利影响上花费了大量的精力,但是猪地方性肺炎仍继续给全球养猪生产造成重大的经济损失。猪肺炎支原体通常是通过引进亚临床型感染的动物而侵入猪群的,或通过短距离的空气传播发生感染,但后一种情况较少。一旦侵入猪群,猪肺炎支原体可通过与受感染的母猪直接接触而将病原体传给后代或在同圈猪只之间进行传播。用于诊断猪肺炎支原体感染的“黄金标准”技术——细菌学培养非常费劲,通常很少使用。酶联免疫吸附试验和聚合酶链式反应检测方法以及以屠宰场监测或田间剖解为形式的死后检查,是用于调查猪肺炎支原体是否参与了猪呼吸道疾病的最常用技术。这些技术已被用来监测受猪地方性肺炎影响的猪群猪肺炎支原体的临床型和亚临床型感染猪群、免疫猪群或非免疫猪群以及处于不同的生产条件和管理奈件下的猪群的发生情况。猪场水平上的猪地方性肺炎临床过程差异以及猪肺炎支原体疫苗接种效果的差异表明,猪肺炎支原体的不同田间分离株的传播和毒力特性存在差异。本文综述了猪肺炎支原体感染的流行病学最新知识,包括其传播、感染和血清转化动力学,并且还比较了用来监测猪地方性肺炎的各种流行病学方法。 | Marina Sibila Maria Pieters Thomas Molitor Dominiek Maes Freddy Haesebmuck Joaquim Segal e s 沈权(译) 邵嘉佳(校) | 2009 | 国外畜牧学(猪与禽)2009，，3： | 16 |
| 2 | Computed tomography-guided percutaneous core needle biopsy in pancreatic tumor diagnosis显示文摘AIM: To evaluate the techniques, results, and complications related to computed tomography(CT)-guided percutaneous core needle biopsies of solid pancreatic lesions.METHODS: CT-guided percutaneous biopsies of solid pancreatic lesions performed at a cancer reference center between January 2012 and September 2013 were retrospectively analyzed. Biopsy material was collected with a 16-20 G Tru-Core needle(10-15 cm; Angiotech, Vancouver, CA) using a coaxial system and automatic biopsy gun. When direct access to the lesion was not possible, indirect(transgastric or transhepatic) access or hydrodissection and/or pneumodissection maneuvers were used. Characteristics of the patients, lesions, procedures, and histologic results were recorded using a standardized form. RESULTS: A total of 103 procedures included in the study were performed on patients with a mean age of 64.8 year(range: 39-94 year). The mean size of the pancreatic lesions was 45.5 mm(range: 15-195 mm). Most(75/103, 72.8%) procedures were performed via direct access, though hydrodissection and/or pneumodissection were used in 22.2%(23/103) of cases and indirect transhepatic or transgastric access was used in 4.8%(5/103) of cases. Histologic analysis was performed on all biopsies, and diagnoses were conclusive in 98.1%(101/103) of cases, confirming3.9%(4/103) of tumors were benign and 94.2%(97/103) were malignant; results were atypical in 1.9%(2/103) of cases, requiring a repeat biopsy to diagnose a neuroendocrine tumor, and surgical resection to confirm a primary adenocarcinoma. Only mild/moderate complications were observed in 9/103 patients(8.7%),and they were more commonly associated with biopsies of lesions located in the head/uncinate process(n =8), than of those located in the body/tail(n = 1) of the pancreas, but this difference was not significant.CONCLUSION: CT-guided biopsy of a pancreatic lesion is a safe procedure with a high success rate, and is an excellent option for minimally invasive diagnosis. | Chiang J Tyng Maria Fernanda A Almeida Paula NV Barbosa Almir GV Bitencourt José Augusto AG Berg Macello S Maciel Felipe JF Coimbra Luiz Henrique O Schiavon Maria Dirlei Begnami Marcos D Guimares Charles E Zurstrassen Rubens Chojniak | 2015 | World Journal of Gastroenterology2015，21，12： | 14 |
| 3 | Hepatocellular carcinoma: Review of disease and tumor biomarkers显示文摘Hepatocellular carcinoma(HCC) is a common malignancy and now the second commonest global cause of cancer death. HCC tumorigenesis is relatively silent and patients experience late symptomatic presentation. As the option for curative treatments is limited to early stage cancers, diagnosis in non-symptomatic individuals is crucial. International guidelines advise regular surveillance of high-risk populations but the current tools lack sufficient sensitivity for early stage tumors on the background of a cirrhotic nodular liver. A number of novel biomarkers have now been suggested in the literature, which may reinforce the current surveillance methods. In addition, recent metabonomic and proteomic discoveries have established specific metabolite expressions in HCC, according to Warburg's phenomenon of altered energy metabolism. With clinical validation, a simple and non-invasive test from the serum or urine may be performed to diagnose HCC, particularly benefiting low resource regions where the burden of HCC is highest. | Jin Un Kim Mohamed I F Shariff Mary M E Crossey Maria Gomez-Romero Elaine Holmes I Jane Cox Haddy K S Fye Ramou Njie Simon D Taylor-Robinson | 2016 | World Journal of Hepatology2016，8，10： | 13 |
| 4 | Is there a role for Tc-99m (V) DMSA scintigraphy in ischemic colitis?显示文摘AIM: To evaluate the role of pentavalent Tc-99m dimercaptosuccinic acid [Tc-99m (V) DMSA] in the diagnosis of ischemic colitis. METHODS: Fourteen patients with endoscopically and histologically confirmed ischemic colitis were included in the study. Tc-99m (V) DMSA scintigraphy was performed within 2 d after colonoscopy. Images were considered positive when an area of increased activity was observed in the region of interest and negative when no abnormal tracer uptake was detected. RESULTS: In 3 out of the 14 patients, Tc-99m (V) DMSA images showed moderate activity in the bowel. The scintigraphic results corresponded with the endoscopic findings. In the other 11 patients, no abnormal tracer uptake was detected in the abdomen. CONCLUSION: Besides the limited number of patients, Tc-99m (V) DMSA could not be considered as a useful imaging modality for the evaluation of ischemic colitis. | Maria I Stathaki Ioannis E Koutroubakis Sophia I Koukouraki Elias A Kouroumalis Nikolaos S Karkavitsas | 2008 | World Journal of Gastroenterology2008，14，35： | 4 |
| 5 | Vitamin D Treatment and Mortality in Chronic Kidney Disease: A Systematic Review and Meta-Analysis显示文摘 | Duranton Flore Rodriguez-ortiz Maria E Duny Yohan Rodriguez Mariano Daur?s Jean-pierre Argil?s Angel | 2013 | American Journal of Nephrology2013，，3： | 2 |
| 6 | Langerhans cells utilize CDla and langerin to efficiently present nonpeptide antigens to T cells显示文摘 | Robert E H Peter A S Maria T | 2004 | J Clin Invest2004，113，5： | 1 |
| 7 | First record of Cyrtophora citricola (Forsskal) in Brazil (Araneae, Araneidae) 显示文摘 | ALVARES E S S DE MARIA M | 2004 | Revista brasileira de zoologia2004，21，： | 1 |
| 8 | Office hysteroscopy and compliance:mini-hysteroscopy versus traditional hysteroscopy in a randomized trial显示文摘 | Carlo D Giuseppina S Maria E | 2003 | Hum Reprod2003，18，： | 1 |
| 9 | Combined pcr-heteroduplex mobility assay for detection and differentiation of influenza A viruses from different animal species显示文摘 | Joanna S E Maria Z | 2001 | Journal of Clinical Microbiology2001，39，11： | 1 |
| 10 | Fluence-to-dose conversion coefficients for neu- trons and protons calculated using the PHITS code and ICRP/ICRU adult reference computa- tional phantoms显示文摘 | TATSUHIKO S AKIRA E MARIA Z | 2009 | Physics in Medicine and Bi- ology2009，54，7： | 1 |
| 11 | Characterization of a bacteriocin-like substance produced by a vaginal lactobacillus salivarius strain显示文摘 | Virginia S O Aida A P Maria E N | 1999 | Appl Environ Microbiol1999，65，5： | 1 |
| 12 | Mapping of the K^+/Na^+ discrimination locus Knal in wheat 显示文摘 | Dubcovsky J Maria G S Epstein E | 1996 | Theoretical and Applied Genetics1996，92，： | 1 |
| 13 | 1-Deoxy-D-xy- lulose 5-phosphate reductoisomerase and plastid isoprenoid biosyn- thesis during tomato fruit ripening 显示文摘 | RODRtGUEZ-CONCEPCION M AHUMADA I DIEZ-JUEZ E SAURET-GUETO S MARIA LOIS L GALLEGO F CAR- RETERO-PAULET L CAMPOS N BORONAT A | 2001 | Plant J2001，27，3： | 1 |
| 14 | DNA vaccines induce partial protection against Leishmania mexicana 显示文摘 | Dumonteil E Maria Jesus R S Javier E O | 2003 | Vaccine2003，21，1718： | 1 |
| 15 | Collabo-rative business process technologies显示文摘 | MARIA E ORLOWSKA SHAZIA S | 2005 | Data & Knowledge Engineering2005，52，： | 1 |
| 16 | Collagen in the tissues of squid (Illex argentius and Loligo Patagonica)-content and solubility 显示文摘 | Maria S Zdzislaw E S | 1987 | Journal of Food Biochemistry1987，11，2： | 1 |
| 17 | The HI haplotype of the tau gene (MAPT) is associated with mild cognitive impairment 显示文摘 | Di Maria E Cammarata S Parodi MI | 2010 | J Alzheimers Dis2010，19，3： | 1 |
| 18 | Ankle-brachial index as a predictor of the extent of coronary atherosclerosis and cardiovascular events in patients with coronary artery disease显示文摘 | Christos M Papamichael John P Lekakis Kimon S Stamatelopoulos Theodoros G Papaioannou Maria K Alevizaki Adriana T Cimponeriu John E Kanakakis Aggeliki Papapanagiotou Anastasios Th Kalofoutis Stamatios F Stamatelopoulos | 2000 | The American Journal of Cardiology2000，，6： | 1 |
| 19 | Role of preoperative ultrasonography in the surgical management of patients with thyroid cancer显示文摘 | Maria A Kouvaraki Suzanne E Shapiro Bruno D Fornage Beth S Edeiken-Monro Steven I Sherman Rena Vassilopoulou-Sellin Jeffrey E Lee Douglas B Evans | 2003 | Surgery2003，，6： | 1 |
| 20 | Optimization and validation of a UV-HPLC method for vitamin C determination in strawberries (Fragaria ananassa Duch), using experimental designs显示文摘 | FraneoV Mafia E Maria S | 2012 | Food Anal Methods2012，5，5： | 1 |
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