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5篇 您的检索式:作者名="Maria Laura Bacci"
    题名 作者 年代 出处 被引量
1Baseline airway inflammation may be a determinant of the response to ozone exposure in asthmatic patients显示文摘Maria Laura Bartoli Barbara Vagaggini Laura Malagrinò Elena Bacci Silvana Cianchetti Federico L. Dente Federica Novelli Francesco Costa Pierluigi Paggiaro 2013Inhalation Toxicology2013,,3:2
2Procalcitonin gene expression after LPS stimulation in the porcine animal model显示文摘Augusta Zannoni Massimo Giunti Chiara Bernardini Fabio Gentilini Andrea Zaniboni Maria Laura Bacci Monica Forni 2011Research in Veterinary Science2011,,2:1
3Inhaled fluticasone propionate is effective as well as oral prednisone in reducing sputum eosinophilia during exacerbations of asthma which do not require hospitalization显示文摘Antonella Di Franco Elena Bacci Maria Laura Bartoli Silvana Cianchetti Federico L. Dente Mauro Taccola Barbara Vagaggini Margherita Zingoni Pier Luigi Paggiaro 2005Pulmonary Pharmacology & Therapeutics2005,,5:1
4Prevention of neointimal hyperplasia associated with modified stretch expanded polytetrafluoroethylene hemodialysis grafts (Gore) in an experimental preclinical study in swine显示文摘Massimiliano Gessaroli Cristiano Bombardi Massimo Giunti Maria Laura Bacci 2012Journal of Vascular Surgery2012,,1:1
5Ex vivo effect of vascular wall stromal cells secretome on enteric ganglia显示文摘BACKGROUND Mesenchymal stromal cell(MSC)-based therapy is currently under study to treat inflammatory bowel diseases.MSC bioactive products could represent a valid alternative to overcome issues associated with systemic whole-cell therapies.However,MSC anti-inflammatory mechanisms differ between rodents and humans,impairing the reliability of preclinical models.AIM To evaluate the effect of conditioned medium(CM)derived from porcine vascular wall MSCs(pVW-MSCs)on survival and differentiation of porcine and guinea pig enteric ganglia exposed to lipopolysaccharide(LPS).METHODS Primary cultures of enteric ganglia were obtained by mechanic and enzymatic digestion of ileum resections from guinea pigs(Cavia porcellus)(GPEG)and pigs(Suus scrofa)(PEG).pVW-MSCs were derived by enzymatic digestion from vascular wall resections of porcine aorta and tested by immunoflowcytometry for MSC immune profile.Enteric ganglia were treated with increasing concentrations of LPS,CM derived by pVW-MSCs or a combination of CM and LPS 1μg/mL.Cell count and morphometric analysis of HuD positive neurons and glial fibrillary acidic protein positive glial cells were performed by immunofluorecent staining of cultured ganglia.RESULTS PEG showed a higher number of neurons compared to GPEG.Overall,CM exerted a protective role on LPS-treated enteric ganglia.CM in combination with LPS increased the number of glial cells per ganglion in both cultures evoking glial cells differentiation in porcine cultures.CONCLUSION These findings suggest an immunomodulating activity of pVW-MSCs mediators on the enteric nervous system in inflammatory conditions.Giovanni Dothel Chiara Bernardini Augusta Zannoni Maria Rosaria Spirito Roberta Salaroli Maria Laura Bacci Monica Forni Fabrizio De Ponti 2019World Journal of Gastroenterology2019,25,33:0
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