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| 1 | 中国澳门非瓣膜病性心房颤动患者的栓塞及抗凝治疗临床调查显示文摘目的:通过对仁伯爵综合医院就诊的非瓣膜病性心房颤动(房颤)患者数据的分析,揭示中国澳门非瓣膜病性房颤患者抗栓治疗的现状。方法:纳入2014-01至2014-12期间共472例非瓣膜病性房颤患者,平均年龄为(73.4±10.9)岁,女性197例(41.7%),年龄≥75岁的患者244例(51.7%)。分析患者的一般特征、临床特征及抗栓治疗,并计算CHA2DS2-VASc评分,评分≥2分为卒中高危;计算HAS-BLED评分,评分≥3分为出血高危。结果:472例患者的平均CHA2DS2-VASc评分为(3.4±1.8)分,CHA2DS2-VASc≥2分的患者有389例(82.4%);平均HAS-BLED评分为(1.96±1.03)分,HAS-BLED评分≥3分的患者有132例(28.0%)。接受抗血小板治疗的患者184例(38.9%),华法林101例(21.6%),新型口服抗凝药物156例(33.8%);同时接受抗血小板和抗凝治疗的患者22例(4.6%);未用任何抗栓治疗的患者53例(11.2%)。卒中高风险患者抗凝治疗率高,215例(55.3%)CHA2DS2-VASc评分≥2分的患者接受了抗凝治疗,新型抗凝药物应用比例超过华法林。结论:中国澳门地区非瓣膜病性房颤患者具有较高的卒中风险,超过80%的患者CHA2DS2-VASc评分≥2分,多数患者依据卒中危险评分进行抗凝治疗,55.3%的患者接受了抗凝治疗,且新型口服抗凝药物应用超过华法林。 | 陈若菡 穆岱明 林如波 叶文辉 Jose Lima 招漫玲 Kyisoe Mario Evora 陈柯萍 | 2016 | 中国循环杂志2016，31，12： | 6 |
| 2 | Trans-brachial artery access for coronary artery procedures is feasible and safe: data from a single-center in Macao显示文摘Compared with trans-femoral artery access (TFA), trans-radial artery access (TRA) for percutaneous coronary interventions (PCI) has been shown to significantly reduce 30-day mortality, in-hospital major adverse cardiac and cardiovascular events (a composite of 30-day mortality and in-hospital myocardial re-infarction, target vessel revascularization, and cerebrovascular events), major bleeding, and access site complications.[1] TRA is more easily compressible, minimizing hematoma risk, and lower crossover rates to another access. Patients may ambulate immediately after procedure, that hospitalization can be shortened significantly. In some centers, patient with TRA can be discharged on the same day of procedure. It is also superior to TFA with closure devices, and becomes the preferred access site for recent PCI.[2] | U Po Lam Edmundo Patricio Lopes Lao Kan Chit Lam Mario Evora Na-Qiong Wu | 2019 | Chinese Medical Journal2019，，12： | 2 |
| 3 | The aging burden of hospitalization for heart failure in Chinese populations:evidence from the Macao Heart Failure Study显示文摘Objective To assess the aging burden of hospitalization for heart failure in Chinese populations in Macao.Methods The Macao Heart Failure Study consists of patients hospitalized with a diagnosis of acute heart failure(AHF)at Centro Hospitalar Conde de São Januário(the only public hospital that provides medical care for the approximately 600,000 residents of Macao)from January 2014 to December 2016.First,we investigated the relationship between socioeconomic development and epidemiological characteristics of HF in Macao.Then we assessed the patients’clinical features and outcomes according to the age groups.Results A total of 967 patients were included in the final analysis.The median age at admission was 82 years old.The advanced age at the admission of HF in Macao was significantly associated with a high-income level and the aging population structure.Marked heterogeneity existed in the epidemiological characteristics,clinical features,utilization of evidence-based therapies,short-and long-term outcomes,and prognostic utility of clinical variables among the different age groups.Conclusion Rapid economic development and significantly aging populations have produced a profound impact on the epidemiological characteristics of HF in Chinese populations.Acute decompensated heart failure(ADHF)is predominantly a disease of the elderly in Macao,and a significant heterogeneity exists in the clinical features,managements,and outcomes among different age groups.Age-based risk stratification models and multidisciplinary HF teams are urgently needed to improve the management and outcomes of hospitalized heart failure(HHF)patients. | Zhi-Nan LU Mario Evora Edmundo Lao Man Ieng Pun Weng Hong Pun Monica Pon Kong Chu Pui I Ieong Toi-Meng Mok Yong-Jian WU | 2020 | Journal of Geriatric Cardiology2020，17，9： | 2 |
| 4 | Recurrent Cardiac Tamponade from Right Atrial Angiosarcoma显示文摘 | Na-Qiong Wu Edmundo Patricio Lopes Lao U Po Lain Yuk Ching Yip Mario Evora | 2018 | Chinese Medical Journal2018，，11： | 1 |
| 5 | 澳門地區心房顫動患病率先導計劃研究显示文摘目的調查澳門地區高血壓病或糖尿病的老年人房顫患病率、初診CHA_(2)DS_(2)-VASc卒中風險評分,以及患者對房顫的認識程度。方法2019年1月~3月,在門診年齡≥65歲,伴有高血壓病或糖尿病患者中,隨機抽樣210例患者(本院75例,仁伯爵醫院135例),採用AliveCor程式初篩可疑房顫患者,後經心電圖檢查確診後行CHA_(2)DS_(2)-VASc評分;並在每例入選患者中進行房顫知識問卷調查。結果所調查210例患者(本院75例,仁伯爵醫院135例),其中男性97例,女性113例,平均年齡(74.16±7.08)歲。採用AliveCor程式初篩可疑房顫5例,後經心電圖檢查確診為房顫患者2例(本院1例,仁伯爵醫院1例)。患病率為0.95%。2例房顫患者性別女性,年齡分別為68歲和84歲。其CHA_(2)DS_(2)-VASc卒中風險評分分別為3和5分。房顫知曉率為66%;房顫導致相關症狀知曉率為5.5%;瞭解關於房顫導致卒中風險增加知曉率為5.5%。結論這是澳門地區首次開展房顫流行病學調查的先導計劃研究,希望後期通過科學的流行病學調查的方法,明確澳門地區人群房顫患病率,尋找適合地區人文地域特點的房顫早期診斷方法和干預模式。 | 陳菡子 馮秀華 招漫玲 Mario Evora 吳燕儀 麥惠芝 吳寶群 陳少穎 謝鴻發 | 2020 | 镜湖医学2020，20，2： | 0 |
| 6 | 澳门地区心房颤动患者的临床调查显示文摘目的了解目前澳门地区心房颤动(房颤)的临床特点和治疗现状,为进一步研究奠定基础。方法选取澳门山顶医院心脏科门诊就诊的房颤患者,登记患者的人口学特征、临床特征、抗凝及抗心律失常药物治疗情况及并发症发生情况。结果从2014年1月至2014年12月,共有652例患者入选,平均年龄为(72.1±11.5)岁,女320例(49%),年龄≥80岁的患者211例(32.3%),合并高血压患者410例(62.9%),合并血栓栓塞事件患者135例(20.7%)。瓣膜性和非瓣膜性房颤患者分别为180例和472例(27.6%和72.4%)。患者平均CHA2DS2-VASc评分3.2分,CHA2DS2-VASc≥2分的患者519例(79.6%)。接受抗凝治疗的患者257例(54.4%),其中华法林101例(21.4%),非维生素K口服抗凝药156例(33.0%)。结论澳门地区房颤患者平均年龄较大,瓣膜性房颤比例较高。房颤患者接受抗凝治疗比例高,脑卒中的发生率较低。 | 陈若菡 穆岱明 陈柯萍 林如波 叶文辉 Kyisoe Jose Lima Mario Evora 张澍 | 2016 | 中华心律失常学杂志2016，20，6： | 0 |
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