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12篇 您的检索式：作者名="Marjan L"

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		题名	作者	年代	出处	被引量
	1	Legalon-SIL downregulates HCV core and NS5A in human hepatocytes expressing full-length HCV显示文摘AIM: To determine the effect of Legalon-SIL (LS) on hepatitis C virus (HCV) core and NS5A expression and on heme oxygenase-1 (HMOX-1) and its transcriptional regulators in human hepatoma cells expressing full length HCV genotype 1b. METHODS: CON1 cells were treated with 50 μmol/L or 200 μmol/L LS. Cells were harvested after 2, 6 and 24 h. HCV RNA and protein levels were determined by quantitative real-time polymerase chain reaction and Western blotting, respectively. RESULTS: HCV RNA (core and NS5A regions) wasdecreased after 6 h with LS 200 μmol/L (P < 0.05). Both 50 and 200 μmol/L LS decreased HCV RNA levels [core region (by 55% and 88%, respectively) and NS5A region (by 62% and 87%, respectively) after 24 h compared with vehicle (dimethyl sulphoxide) control (P < 0.01). Similarly HCV core and NS5A protein were decreased (by 85%, P < 0.01 and by 65%, P < 0.05, respectively) by LS 200 μmol/L. Bach1 and HMOX-1 RNA were also downregulated by LS treatment (P < 0.01), while Nrf2 protein was increased (P < 0.05).CONCLUSION: Our results demonstrate that treatment with LS downregulates HCV core and NS5A expression in CON1 cells which express full length HCV genotype 1b, and suggests that LS may prove to be a valuable alternative or adjunctive therapy for the treatment of HCV infection.	Marjan Mehrab-Mohseni Hossein Sendi Nury Steuerwald Sriparna Ghosh Laura W Schrum Herbert L Bonkovsky	2011	World Journal of Gastroenterology2011，17，13：	3
	2	显示文摘	Esther L Marion G Marjan S	2002	Arterioscler Thromb Vasc Biol2002，22，：	1
	3	Explaining slow diffusion of energy-saving technologies a vintage model with returns to diversity and learning-by-using显示文摘	PETER MULDER HENRI L F DE GROOT MARJAN W HOFKES	2003	Resource and Energy Economics2003，25，1：	1
	4	Material tailoring of the femoral component in a total knee replacement to reduce the problem of aseptic loosening 显示文摘	Marjan B Sahari B B Edwards K L	2013	Materials and Design2013，52，：	1
	5	Material tailoring of the femoral component in a total knee replacement to reduce the problem of aseptic loosening 显示文摘	Marjan B Sahari B B Edwards K L	2013	Materials & Design2013，52，：	1
	6	Localization of lipoxy- genases 1 and 2 in germinating soybean seeds by an indirect immunofluorescence technique 显示文摘	Marjan Vernooy-Gerritsen Adri L M Bos Gerrit A Veldink Johannes F G Vliegenthart	1983	Techni Plant Physiol1983，73，2：	1
	7	Underestimation of atypical ductal hyperplasia at MRI-guided 9-gauge vacuum-assisted breast biopsy 显示文摘	Liberman L Holland AE Marjan D		AJR Am J Roentgenol0，188，3：	1
	8	Underestimation of atypicalductal hyperplasia at MRI-guided 9-gauge vacuum-assisted breast biopsy显示文摘	Uberman L Holland AE Marjan D	2007	AJR Am J Roentgenol2007，188，3：	1
	9	Transforming growth factor-β mediates balance between flammation and fibrosis during plaque progression显示文摘	Esther L Marion G Marjan S	2002	Arterioscler Thromb Vasc Biol2002，22，：	1
	10	Intermolecular Interactions and Dynamics in Polymer/C60 Blends 显示文摘	Peter A M Marjan L	2010	Macromolecules2010，，43：	1
	11	Exploration and exploitation in evolutionary algorithms: a survey 显示文摘	Matej C Shin H L Marjan M	2013	ACM Computing Surveys2013，45，3：	1
	12	An Emergency Department-Based Brief Intervention for Veterans at Risk for Suicide (SAFE VET)显示文摘	Kerry L Knox Barbara Stanley Glenn W Currier Lisa Brenner Marjan Ghahramanlou-Holloway Gregory Brown	2012	American Journal of Public Health2012，，：	1

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