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| 1 | Studies on the allostimulatory function of dendritic cells from HCV-HIV-1 co-infected patients显示文摘There is increasing recognition of the potential morbidity and mortality associated with HIV-1 and hepatitis C (HCV)co-infection. HIV appears to adversely affect HCV disease while the reciprocal effect of HCV on HIV remains controversial.We therefore studied the effect of co-infection on dendritic cell function versus HIV infection alone, as previous work has shown that HCV impairs dendritic cell (DC) function. HIV-1 positive individuals with HCV were matched for CD4count, HIV- 1 RNA viral load and therapy, to HIV- 1 positive patients without HCV. Monocyte-derived DC were generated and mixed leukocyte reactions were performed. We assessed allostimulatory capacity with and without administration of exogenous Thl cytokines, using thymidine uptake and cell division analyses with the vital dye CFSE. We found that monocyte-derived DC from co-infected individuals showed no significant differences in allostimulatory capacity to ex vivo generated DC from HIV-1 infected individuals without HCV. Unlike the situation with HCV infection alone, this impairment was not reversed by increasing concentrations of either interleukin-2 or -12. Monocyte-derived DC from HIV-1 and HCV co-infected individuals have a similar allostimulatory capacity to DC from matched patients with HIV-1alone. These findings are compatible with results of prior clinical studies that found no evidence that HCV co-infection altered HIV disease progression and has implications for immunotherapeutic approaches in co-infected individuals. | Justin STEBBING Steve PATTERSON Simon PORTSMOUTH Claire THOMAS Robert GLASSMAN Adrian WILDFIRE Frances GOTCH Mark BOWER Mark NELSON Brian GAZZARD | 2004 | Cell Research2004,14,3: | 1 |
| 2 | Immune-Complex Glomerulonephritis in Crohn?s Disease显示文摘 | Mark Glassman Matthew Kaplan William Spivak | 1986 | Journal of Pediatric Gastroenterology and Nutrition1986,,6: | 1 |
| 3 | Retrospective drug utilization review:incidence of clinically relevant potential drug-drug interactions in a large ambulatory population显示文摘 | Peng CC Glassman PA Marks I | 2003 | Journal of Managed Care Pharmacy2003,9,6: | 1 |
| 4 | Anorectal Motility Abnormalities in Children with Encopresis and Chronic Constipation显示文摘 | Neeraj Raghunath Mark S. Glassman Michael S. Halata Stuart H. Berezin Julian M. Stewart Marvin S. Medow | 2011 | The Journal of Pediatrics2011,,2: | 1 |
| 5 | Syntactic clustering of the Web显示文摘 | Andrei Z Broder Steven C Glassman Mark S Manass~ | 1997 | Computer Networks and ISDN Systems1997,29,813: | 1 |
| 6 | Syntactic clustering of the Web显示文摘 | Andrei Z. Broder Steven C. Glassman Mark S. Manasse Geoffrey Zweig | 1997 | Computer Networks and ISDN Systems1997,,8: | 1 |
| 7 | Syntactic clustering of the Web显示文摘 | Andrei Z. Broder Steven C. Glassman Mark S. Manasse Geoffrey Zweig | 1997 | Computer Networks and ISDN Systems1997,,8: | 1 |
| 8 | 卡车持续热销显示文摘美国的汽车销售或许在放缓,但美国人对运动型多功能车(SUV)的热爱却只增不减。在过去38个月的每个月里,SUV、皮卡和厢式货车的销量都占到全美轻型车(包括小汽车)销量的一半以上。 | Mark Glassman 陶梦萦 | 2016 | 商业周刊(中文版)2016,0,14: | 0 |
| 9 | 信用评级压力线显示文摘当评级机构对一个国家偿债能力的评估即将发生变化时,那就是它们在对投资者发出警报。标准普尔对其每个评级都赋予不同的前景评估(正面、稳定或负面),以预告一国的评级是否处于上调或下调的边缘。如今,负面评估的数量略多于正面评估。 | Mark Glassman 永年 | 2015 | 商业周刊(中文版)2015,0,19: | 0 |
| 10 | 美国vs中国显示文摘在本轮美国总统竞选中,中国话题是胜选者不得不面对的最复杂挑战。让我们通过他们的视角。 | Peter Coy Michael C. Bender Mark Glassman Natalie Kitroeff Ting Shi Joe Sobcyk | 2016 | 商业周刊(中文版)2016,0,1: | 0 |
| 11 | Correlations数读婚姻与贫困显示文摘经营婚姻并非易事,但备胎选择可能更糟,至少在财务上如此。美国政府问责办公室的报告显示,65岁以上人士中位于贫困线以下的,单身者比已婚者的概率要高得多。 | Mark Glassman 竹西(译) | 2014 | 商业周刊(中文版)2014,,7: | 0 |
| 12 | Correlations数读 最实在的圣诞礼物显示文摘每年,美国消费者为朋友和家人购买的节日礼物中,价值数十亿美元的东西最终都将被退回。然而,如今有一种办法可以帮助消费者更容易地确定哪些商品不要购买。根据美国研究集N(America’s Research Group)编制的年度调查数据,自2000年以来,退回节日礼物的美国人已大幅减少,而购买礼品卡的人数在不断增加。 | Mark Glassman 永年(译) | 2013 | 商业周刊(中文版)2013,,24: | 0 |
| 13 | Correlations数读快消品:GDP先行指标显示文摘耐克成为道琼斯工业平均指数成分股,表明该公司630亿美元市值得到了认可,也显示出消费支出对整体经济的重要性。在道指成分股29家公司中,前六名的季度销售额与美国按年率计算的季度GDP增长率的相关度最为密切。 | Mark Glassman 竹西(译) | 2013 | 商业周刊(中文版)2013,,21: | 0 |
| 14 | 数读:税与走私显示文摘马基纳克公共政策中心的一项研究揭示了美国各州不同香烟税率对走私的刺激程度。2月份公布的研究表明,对于一家之主为40岁以下人士的家庭而言。剔除通胀因素之后,财富的平均水平仍低于2007年的30%。正常年景,年轻的家庭比年老的家庭在家具和汽车上的花费更多。 | Mark Glassman(译) 竹西 | 2014 | 商业周刊(中文版)2014,,8: | 0 |
| 15 | 社交媒体正中影响力的靶心显示文摘预计奢侈品公司2020年将继续与社交媒体大咖们合作。这些模特、运动员以及其他社会名流一他们发布关于品牌的消息内容,以换取一定形式的报酬—今年吸引了品牌的很多行动。在每条消息的互动方面,奢侈品公司超过了其他公司。 | Mark Glassman | 2019 | 商业周刊(中文版)2019,0,23: | 0 |
| 16 | 人往高处走显示文摘智力资本具备流动性,但倾向于集中在少数国家。根据联合国最近发布的有关专利申请的报告,美国仍是全球发明者移民的首选目的地。 | Mark Glassman 永年(译) | 2013 | 商业周刊(中文版)2013,,25: | 0 |
| 17 | 恶性通胀玻利瓦尔的历史性贬值显示文摘委内瑞拉货币玻利瓦尔在过去几个月大幅贬值,该国的现金如今不以张计算,而是靠称重。该国的通胀率在2016年11月迅速跳升,达到历史性高位。 | Ben Bartenstein Mark Glassman 竹西 | 2017 | 商业周刊(中文版)2017,0,1: | 0 |