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| 1 | Chronic kidney disease after nephrectomy in patients with renal cortical tumours: a retrospective cohort study显示文摘 | William C Huang Andrew S Levey Angel M Serio Mark Snyder Andrew J Vickers Ganesh V Raj Peter T Scardino Paul Russo | 2006 | Lancet Oncology2006，，9： | 4 |
| 2 | Reninoma: case report and literature review显示文摘 | Lara Wong Thomas HS Hsu Mark G Perlroth Lawrence V Hofmann Claudia M Haynes Laurence Katznelson | 2008 | Journal of Hypertension2008，，2： | 2 |
| 3 | Reliability and within subject variability ofVE,VO2,heart rate and blood pressure during submaximum cycle ergometry显示文摘 | Becque M D Katch V Marks C | | 0，，04： | 1 |
| 4 | Treatment of traumatic cervical arteriovenous fistulas with N-butyl-2- cyanoacrylate 显示文摘 | Jayaraman M V Do H M Marks M P | 2007 | Am J Neuroradiol2007，28，2： | 1 |
| 5 | Electronic and sterie effects in the dienone-phenol rearrangement of 2-hydroxy-and 2-Alkoxycyclohexa-2,5-dien-1-ones显示文摘 | Frimer A A Marks V Sprecher M | 1994 | The Journal of Organic Chemistry1994，59，： | 1 |
| 6 | Different strategies to develop an electrochemical thrombin aptasensor显示文摘 | Monica M Mark V Katakis I | 2006 | Electrochem Commun2006，8，： | 1 |
| 7 | Histone deacetylase inhibitors as new anticancer drugs显示文摘 | Marks P A Richon V M Breslow R | 2001 | Curr Opin Oncol2001，13，6： | 1 |
| 8 | A 4Ar/39 Ar and U/Pb isotopic study of the Ilimaussaq complex, South Green- land: Implications for the 40K decay constant and for the'dura- tion of magmatic activity in a peralkaline complex显示文摘 | Krumrei T V Villa I M Marks M A W | 2006 | Chemical Geology2006，227，： | 1 |
| 9 | Evaluation and analysis of soil washing for seven lead-contaminated soils显示文摘 | Mark R M William H Y | 1997 | Journal of Environmental Engineering1997，3，： | 1 |
| 10 | Histone deacetylases and cancer:causes and therapies显示文摘 | Marks P A Rifkind R A Richon V M | 2001 | Nature2001，1，3： | 1 |
| 11 | Histone deacetylases and cancer:causes and therapies显示文摘 | MARKS P RIFKIND R A RICHON V M | 2001 | Nat Rev Cancer2001，1，3： | 1 |
| 12 | Seedling survival and growth of four Shorea species in a Sri Laankan rainforest显示文摘 | Mark P Ashton M S Gunatilleke C V S | 1995 | J Trop Ecol1995，11，： | 1 |
| 13 | Quantitation of mRNA by the polymerase chain reaction 显示文摘 | Wang A M Doyle M V Mark D F | 2000 | Leukemia2000，14，2： | 1 |
| 14 | Phage therapy reduces Campylobacterjejuni colonization in broilers显示文摘 | JAAP A W MARCEL A P V B MARK A M | 2005 | Veterinary Microbilogy2005，109，： | 1 |
| 15 | Histone deacetylase inhibitors: inducers of dill--erentiation or apoptosis of transformed cells 显示文摘 | Marks P A Richon V M Rifkind R A | 2000 | J Natl Cancer Inst2000，92，15： | 1 |
| 16 | Descriptive epidemiology of ache vulgaris in the community 显示文摘 | STATHAKIS V KILKENNY M MARKS R | 1997 | Australas J Dermatol1997，38，3： | 1 |
| 17 | Histone deaeetylases and cancer: causes and therapies 显示文摘 | Marks P Rifkind R A Richon V M | 2001 | Nat Rev Caneer2001，1，3： | 1 |
| 18 | PAHs in the Fraser River basin: a critical appraisal of PAH ratios as indicators of PAIl source and composition 显示文摘 | Mark B Y Robie W M Roxanne V | 2002 | Organic Geochemistry2002，33，： | 1 |
| 19 | His- tone deacetylase inhibitors 显示文摘 | MARKS P A RICHON V M MILLER T | 2004 | Adv Cancer Res2004，91，： | 1 |
| 20 | Tranexamic acid for intracerebral haemorrhage within 2 hours of onset: protocol of a phase Ⅱ randomised placebo-controlled double-blind multicentre trial显示文摘Rationale Haematoma growth is common early after intracerebral haemorrhage(ICH),and is a key determinant of outcome.Tranexamic acid,a widely available antifibrinolytic agent with an excellent safety profile,may reduce haematoma growth.Methods and design Stopping intracerebral haemorrhage with tranexamic acid for hyperacute onset presentation including mobile stroke units(STOP-MSU)is a phase Ⅱ double-blind,randomised,placebo-controlled,multicentre,international investigator-led clinical trial,conducted within the estimand statistical framework.Hypothesis In patients with spontaneous ICH,treatment with tranexamic acid within 2 hours of onset will reduce haematoma expansion compared with placebo.Sample size estimates A sample size of 180 patients(90 in each arm)would be required to detect an absolute difference in the primary outcome of 20%(placebo 39%vs treatment 19%)under a two-tailed significance level of 0.05.An adaptive sample size re-estimation based on the outcomes of 144 patients will allow a possible increase to a prespecified maximum of 326 patients.Intervention Participants will receive 1 g intravenous tranexamic acid over 10 min,followed by 1 g intravenous tranexamic acid over 8 hours;or matching placebo.Primary efficacy measure The primary efficacy measure is the proportion of patients with haematoma growth by 24±6 hours,defined as either≥33%relative increase or≥6 mL absolute increase in haematoma volume between baseline and follow-up CT scan.Discussion We describe the rationale and protocol of STOP-MSU,a phase Ⅱ trial of tranexamic acid in patients with ICH within 2 hours from onset,based in participating mobile stroke units and emergency departments. | Nawaf Yassi Henry Zhao Leonid Churilov Bruce C V Campbell Teddy Wu Henry Ma Andrew Cheung Timothy Kleinig Helen Brown Philip Choi Jiann-Shing Jeng Annemarei Ranta Hao-Kuang Wang Geoffrey C Cloud Rohan Grimley Darshan Shah Neil Spratt Der-Yang Cho Karim Mahawish Lauren Sanders John Worthington Ben Clissold Atte Meretoja Vignan Yogendrakumar Mai Duy Ton Duc Phuc Dang Nguyen Thai My Phuong Huy-Thang Nguyen Chung Y Hsu Gagan Sharma Peter J Mitchell Bernard Yan Mark W Parsons Christopher Levi Geoffrey A Donnan Stephen M Davis | 2022 | Stroke & Vascular Neurology2022，7，2： | 1 |
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