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| 1 | Extracellular matrix synthesis in vascular disease:hypertension,and atherosclerosis显示文摘Extracellular matrix(ECM) within the vascular network provides both a structural and regulatory role.The ECM is a dynamic composite of multiple proteins that form structures connecting cells within the network.Blood vessels are distended by blood pressure and,therefore,require ECM components with elasticity yet with enough tensile strength to resist rupture.The ECM is involved in conducting mechanical signals to cells.Most importantly,ECM regulates cellular function through chemical signaling by controlling activation and bioavailability of the growth factors.Cells respond to ECM by remodeling their microenvironment which becomes dysregulated in vascular diseases such hypertension,restenosis and atherosclerosis.This review examines the cellular and ECM components of vessels,with specific emphasis on the regulation of collagen type I and implications in vascular disease. | Markella Ponticos Barbara D.Smith | 2014 | The Journal of Biomedical Research2014，28，1： | 12 |
| 2 | Enhanced fat degradation following the addition of a Pseudomonas species to a bioaugmentation product used in grease traps显示文摘The presence of fats, oils and greases(FOGs) in wastewater can lead to many problems including blockages. Investigation of a bioaugmentation product, consisting of Bacillus spp., to degrade butter(1%, W/V) and olive oil(1%, V/V) was performed in aerobic batch cultures for 13-day incubation. Gravimetric analysis of the remaining substrates showed slowly degradation of the oil after a 2-day lag, but no degradation of the butter. Addition of a Pseudomonas putida strain CP1 to the Bacillus spp. population promoted rapidly degradation of both fats after7 days of incubation. High fat accumulation revealed the potential use of the new bacterial mixture for production of added-value compounds. Lipase production only by the Bacillus spp.along with the analysis of the remaining lipids with thin layer chromatography and gas chromatography, suggested that the Bacillus spp. mainly only hydrolyzed the fat. The breakdown products were metabolized by the Pseudomonas putida CP1 performing preferential utilization of unsaturated fatty acids. Investigation of population dynamics using selective plating and a labeled Pseudomonas putida CP1::Tn7-gfp showed domination of the latter. The new mixture performed a successful cooperation with good potential for FOG treatment and an aggregative response desirable to fat degradation in grease traps. | Markella Tzirita Seraphim Papanikolaou Bríd Quilty | 2019 | Journal of Environmental Sciences2019，31，3： | 2 |
| 3 | Connective tissue growth factor (CCN2) in blood vessels显示文摘 | Ponticos Markella | 2013 | Vascul Pharmacol2013，58，3： | 1 |
| 4 | Dual regulation of the AMP-activated protein kinase provides a novel mechanism for the control of creatine kinase in skeletal muscle 显示文摘 | Markella Ponticos Qi Long Lu Jennifer E Morgan | 1998 | The EMEBO Journal1998，17，： | 1 |
| 5 | Increased Arterial Inflammation Relates to High-Risk Coronary Plaque Morphology in HIV-Infected Patients显示文摘 | Ahmed Tawakol Janet Lo Markella V. Zanni Eleni Marmarelis Ezinne J. Ihenachor Megan MacNabb Bryan Wai Udo Hoffmann Suhny Abbara Steven Grinspoon | 2014 | JAIDS Journal of Acquired Immune Deficiency Syndromes2014，，2： | 1 |
| 6 | Estrogen Sulfotransferase Is Expressed in Subcutaneous Adipose Tissue of Obese Humans in Association with TNF-α and SOCS3显示文摘 | Rexford S. Ahima Takara L. Stanley Victor K. Khor Markella V. Zanni Steven K. Grinspoon | 2011 | The Journal of Clinical Endocrinology & Metabolism2011，，7： | 1 |
| 7 | TNF-c~ Antagonism with Etanercept Decreases Glucoseartd Increases the Proportion of HighMolecularWeightAdiponectin in Obese Subjects with Featuresof the Metabolic Syndrome显示文摘 | Takara LS Markella VZ Stine J el at | 2011 | J ClinEndocrinolMetab2011，96，1： | 1 |
| 8 | Connective tissue growth factor(CCN2) in blood vessels显示文摘 | Ponticos Markella | 2013 | Vascul Pharmacol2013，58，： | 1 |
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