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| 1 | Single-center study comparing computed tomography colonography with conventional colonoscopy显示文摘AIM:To compare the results from computed tomography (CT) colonography with conventional colonoscopy in symptomatic patients referred for colonoscopy. METHODS: The study included 227 adult outpatients, mean age 60 years, with appropriate indications for colonoscopy. CT colonography and colonoscopy were performed on the same day in a metropolitan teaching hospital. Colonoscopists were initially blinded to the results of CT colonography but there was segmental unblinding during the procedure. The primary outcome measures were the sensitivity and specificity of CT colonography for the identification of polyps seen at colonoscopy (i.e. analysis by polyp). Secondary outcome measures included an analysis by patient, extracolonic findings at CT colonography, adverse events with both procedures and patient acceptance and preference. RESULTS: Twenty-five patients (11%) were excluded from the analysis because of incomplete colonoscopy or poor bowel preparation that affected either CT colonography, colonoscopy or both procedures. Polyps and masses (usually cancers) were detected at colonoscopy and CT colonography in 35% and 42% of patients, respectively. Of nine patients with a finaldiagnosis of cancer, eight (89%) were identified by CT colonography as masses (5) or polyps (3). For polyps analyzed according to polyp, the overall sensitivity of CT colonography was 50% (95% CI, 39%-61%) but this increased to 71% (95% CI, 52%-85%) for polyps ≥ 6 mm in size. Similarly, specificity for all polyps was 48% (95% CI, 39%-58%) increasing to 67% (95% CI, 56%-76%) for polyps ≥ 6 mm. Adverse events were uncommon but included one colonic perforation at colonoscopy. Patient acceptance was high for both procedures but preference favoured CT colonography. CONCLUSION: Although CT colonography was more sensitive in this study than in some previous studies, the procedure is not yet sensitive enough for widespread application in symptomatic patients. | Ian C Roberts-Thomson Graeme R Tucker Peter J Hewett Peter Cheung Ruben A Sebben EE Win Khoo Julie D Marker Wayne K Clapton | 2008 | World Journal of Gastroenterology2008，14，3： | 4 |
| 2 | syndromes显示文摘 | Quilici j Banzet N Paule P Circulating endothelial cell count as a diagnostic marker for non-ST-elevation acute coronary | 2004 | Circulation2004，110，10： | 1 |
| 3 | BMP5 and the molecular, skeletal, and soft-tissue alterations in short ear mice显示文摘 | King J A Marker P C Seung K J | 1994 | Dev Biol1994，166，1： | 1 |
| 4 | Postoperative hemodynamic and thermoregulatory conseguences of intraoperative core hypothmia 显示文摘 | Kurz A Sessler DI Marker E | 1995 | J Clin Anesth1995，7，： | 1 |
| 5 | Multiple immuno-regulatory defects in type-1 diabetes 显示文摘 | Kukreja A Cost G Marker J | 2002 | J Clin Invest2002，109，1： | 1 |
| 6 | BMP5 and the molecular,skeletal,and soft-tissue alterations in short ear mice显示文摘 | KINGSLEY D M KING J A MARKER P C | 1994 | Dev Biol1994，166，： | 1 |
| 7 | BMP5and the molecular,skeletal,and soft-tissue alterations in short ear mice显示文摘 | KING J A MARKER P C SEUNG K J | 1994 | Dev Biol1994，166，： | 1 |
| 8 | Spectrum of bmp5 mutations from germline mutagenesis experiments in mice显示文摘 | MARKER P C SEUNG K BLAND A E | 1996 | Genetics1996，145，： | 1 |
| 9 | Functional problems and treatment solutions after total hip arthmplasty 显示文摘 | Bhave A Marker DR Seyler TM | 2007 | J Arthroplasty2007，22，2： | 1 |
| 10 | Organic carbon in the Hmn- ber River显示文摘 | Tipping E Marker A F Butterwick C | 1997 | The Science of total environment1997，195，： | 1 |
| 11 | Multiple immuno-regulatory defects in type-1 diabetes显示文摘 | Kukreja A Cost G Marker J | 2002 | J Clin Invest2002，109，1： | 1 |
| 12 | The formation of rare earth element scavenger minerals in weathering in weathering products derived from alkaline rocks of Se-bahia,Brazil显示文摘 | Marker A De Oliveira J J | 1990 | Chem Geol1990，84，： | 1 |
| 13 | Organization of small area estimators using a generalized linear regression framework 显示文摘 | Marker D A | 1999 | Journal of Official Statistics1999，，15： | 1 |
| 14 | Multiple immuno-regulatory defects in type-1 diabetes 显示文摘 | Kukreja A Cost G Marker J | 2002 | J Clin Invest2002，109，1： | 1 |
| 15 | Endometrial receptivity : clinical assessment in relation to fertility, infertility, and antifertility 显示文摘 | Marker A Singh M | 2006 | Med Res Rev2006，26，6： | 1 |
| 16 | Virus - activated T cells regulate expression of adhesion molecules on endothelial cells in sites of infection显示文摘 | Marker O Seheynius A Christensen JP | 1995 | J Neuroimmunol1995，62，1： | 1 |
| 17 | Serum levels of different chronic heart failure 显示文摘 | Faggiano P DTAloia A Brentana tumour markers in patients with L | 2005 | Eur J HeartFail2005，124，7： | 1 |
| 18 | Postoperative hemodynamic and thermoregulatory conseguences of intraoperative core hypothmia 显示文摘 | Kurz A Sessler DI Marker E | 1995 | J Clin Anesth1995，7，4： | 1 |
| 19 | Multiple immuno-regulatory defects in type-1 diabetes显示文摘 | Kukreja A Cost G Marker J | 2002 | J Clin Invest2002，109，1： | 1 |
| 20 | Gully erosion modelling and landscape response in the Mbuluzi River catchment of Swaziland显示文摘 | Sidorchuk A Marker M Moretti S | 2003 | Catena2003，50，： | 1 |
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